Dear forum members,

A question that might seem trivial but still i prefer to be on the safe side
Visited the dentist today who applied the local anesthetics used in such situations...
Should I change my plans for dmt and harmalas adventure this evening,
Or no interaction should be expected between the chemicals involved ?

Thanks

DMT safely interacts with most drugs. It is difficult to say, however, the result of DMT's interaction with lidocaine since few people have probably tried it. Either way, it doesn't hurt to wait a day.

Local anesthetics used by dentists may also contain adrenaline. This may interact with harmala alkaloids.

I would be most concerned about receiving the anesthetics while still MAO inhibited. After the effects of the anesthetics have worn off, it is probably safe to ingest harmalas.

When smoking the harmala alkaloids, the dose is very much smaller than when ingesting orally, so the risks of interactions are also much lower. Typically, 15 to 25 mg is sufficient when smoked, whereas an oral dose starts at 150 mg.

Unfortunately, not much is known about the interactions of smoked harmalas. In case of doubt, it is better to wait a day.

Thanks for your reply. I am more concerned about the harmalas as I read online that dental anesthetics contains also epinephrine.

p.s. indeed waiting a day will work yet i am still curious about the theory

Thanks pitubo, this confirms my suspicion...