You're analogy with the 'layers' aspect is leaning in the right way. I suppose it may depend on the path you wish to take further. DMT may or may not push you past many layers that you are working through with meditation. Many of times it can burst through more than you can count. Other times it may end up sort of easing beyond some familiar borders (granted, DMT generally has a quite 'unusual' aspect). However I am far from thinking the two (DMT and meditation) are incompatible. The word integration comes up often and I feel it applies here.
Depending on dosage, DMT can aide either. For me, lower dosages invite a lovely calm and meditation-driven mindset that eases back to normalcy. Building up with meditation, study, determination (will) can push even lower physical dosages to higher realms of understanding oneself. Whereas higher dosages may push so far beyond what you had expected in your meditation & studies that the realm is wholly foreign to you and integration is a path of piecing that puzzle back together.
In other words, while it may feel like bursting through can hinder some learning and growth, the opposite may also hold true as after an experience you may have all sorts of ideas in your pot to play or use in recipes of thought as you wish... grand realizations, small tag-along thoughts, sudden wonder.. all have a place to fit in your mind along with your expectations of experience and growth. With that said, I think an understanding of meditation and the mind can be of utmost importance when undertaking a DMT experience.
To answer your ultimate question, though I believe I did above, yes they are compatible. Be sure, be grounded, be open, and when it happens just be. You can take from it what you will, critical thought is welcomed (when back) in our human selves.That's it from me.
Oh, and what a trip
The inner soul is full of joy. Reveal my secrets and sew me whole. With each day, "I" heeds your call.
You may not care the slightest and may not be the brightest, but from here "I" sees you're mighty for you created it all.
And the jumbling sea rose above the wall.
Through this chaos comes the order you enthrall.