Hi there

A FOAF wants to try DMT but he is in a lot of pain and is on quite strong opiate based pain killers, oxycodone or something.

HE states he gets quite high off of them alone (if he takes more than his regular dose) and is curious as to the effect of combining DMT with opiates.

Would this combination be a negative, neutral or a positive thing?
Has anyone done this before?

Question comments welcome

Peace

I have personally done this with no problems. This is a valid question though. Can pain patients share the DMT experience? I know a number of individuals who do precisely this and to my knowledge haven't experienced any adverse reactions as a result of the combination. Caution is always advised though.

The combination of strong mu agonist opioids and vaporised DMT is very pleasant IMO.It does require some knowledge of dosing correctly as too much opiate might make one queasy etc. The anxiolytic effects of opiates can settle the mind for a heftier than normal dose without dulling matters significantly.

My Godhead experience was on insufflated Heroin. IF you take a big enough dose I don't think the body high of opioids will have enough power to keep you tethered to the ground.

Another time I did get nauseous from a sub-breakthrough dose and snorted Roxicodone. Threw up and felt way better.

DMT trips made me rethink opiate use. But, If they're prescribed for chronic pain I guess you gota keep taking them. But yes, the opiate high won't stop the DMT experience although it surely changes its quality. (Somehow more body oriented even at breakthrough doses)

well, I was a twenty year long heroin, opiate, opiod, whatever have you, if it was anything near an opiate buzz, I abused it .. addict
I just got off suboxone five months ago, now my only excursions are with poppy seed tea ...
but what I noticed was the 'dmt elves' used to get on my case about my opiate abuse ... I couldn't have a great breakthrough EVERY time because they'd bring it up from time to time, reminding me that I should work on myself and that I'd be happier if I let go of my destructive vices
Now, sure, I did have breakthroughs on opiates and suboxone BUT, one thing I did notice was if I had to much opiates, then the DMT wouldn't come through as clear and I'd be left with less than I went into it with...
I use DMT for spiritual insight and for facing my inner demons. If one has an addiction that is bad for them and others, DMT will bring it out into the open and make one face it head on..the good side to that is that if one successfully stops using those vices, the following DMT experiences are very rewarding, with the 'elves' or 'dmt beings' congratulating one as if one had corrected a wayward universe from a head on collision course with another....
Also, if one has a Problem with using opiates and KNOWS it, this just may add to the DMT experience in the form of having a self conscious , lets say, 'heavy trip' ..
I suppose if the opiates are being used strictly for pain and responsibly, well, this may then be 100% okay as a combination then ...
But in any sort, I couldn't see long term opiate use alongside DMT, as the Elves will eventually, in my experience, put one in their place by saying, as I've heard MANY times from 'them' myself, " Dont come back til you've gotten cleaned up ! "
So now my use of opiates is wayyyy low .. thanks to DMT !
DMT ..its a Good Thing!

I know that this is an old thread, but regardless I'll mirror what others have said. Opiates (in my/our case Tramadol) and DMT are fine together, I even noticed a correlation between the happy/positive vibe and being under the effects of opiates.

It can be quite euphoric.

Flipside, if you have an opiate addiction and are in any state of withdrawal, it can bring out the demons, BIG TIME.

I suppose this is what I was driving after - a little exorcism of sorts.

Like everything else with psychedelics, imposing a direction never seems to work out so well - so for the time being I'm just going to keep cleaning the house, and I suppose I'll invite guests again once things are in order.

I know this might fly against somes opinions here, but I have a similar story as No Knowing.

Although not technically an opiate, my strongest smoked experience with DMT was 4 years ago, where 2 hours after taking 4g of kratom I loaded my mini bong with a reasonable amount of changa, took it all in one go (which id done several times before without anything close to the result of that afternoon). The experience that followed was the most insanely moving, powerful and life-changing experience id ever had. Nearly instantaneous, full dissolution into the All-That-Is WhiteLight/Godhead. There were simply no words for it. There's actually a massive thread on it under the experience reports section.

It could've just been happenstance that the taking of these two things somehow coincided into what came about. They could've been totally unrelated. I often wonder if it was that little bit of kratom leaf shortly before. I will say though, that if there was some interaction, that the experience was in no way dulled ...heh...quite the opposite.

[Im not condoning taking kratom, nor taking it with changa (or with any form of RIMA inhibition), just relaying my personal experience.]

Not to go off subject, but I'd never even heard of Kratom prior to reading your post.

It looks........ 'interesting'......

I used to take Kratom. I never thought of taking that along with DMT
I do know other opiates tend to dull it's effects BUT, Kratom on the other hand all I know by experience is that it is stimulating in small doses [[ depending what your tolerance is at the time ]] and at higher doses its sedating..
Then we have all the strains and types of kratom available, where it grew, conditions of environment, all key factors to a good and solid, or weak and hit/miss, variety of Kratom so many factors come into play when looking for or obtaining good quality kratom...
I used to get it by the quarter pound, when I was trying to get off suboxone, tramadol, occasional heroin ..
and for the most part it did help and I did get off those drugs.
DMT helped me in that area too, as it's helped many an addict to recover , by making them face themselves and giving us the Courage and Strength to do it ... I don't know anything other than opiate maintenance [[ methadone, suboxone ]] which the most choose, or, cold turkey, which few make it out of, other than DMT and psychedelics, that can cause a person to really get off it
I'd say the glowing experiences I've had with Kratom are far and few between, only a few times did I ever find a 'sweet spot' with it and even then tolerance would negate it soon enough and prevent it from being repeated in another day..
But I could understand kratom adding to the bliss of DMT if one doesn't depend on or is not abusing the kratom
I used to take neurontin before dmt to take off that electric edge and many times 'scary' come-up and I had great experiences that I hadn't had with just plain DMT.
So, yeah I would agree opiates COULD add to the experience but given my twenty year plus addiction to them and experiences, I'd say the combination of the two resulting in such an experience and then being repeatable on demand is almost nil, unless one can show considerable constraint with using the opiates and only do so once in a while or strictly in combination with DMT.. if one can do that then yeah I can see the combo producing wonderful, memorable and blissful glowing experiences more often.
But really, who CAN do that? Not to say people who can are not out there, but as far as I know? Nobody.

A 3 gr of good kratom, 2 - 3 hours in, and a low dose DMT vaped dulled as you said.
But I've come to check later on medium (or higher) doses dmt, it might push trough overriding the kratom, we'll see. It seems it worked like that for Tattvamasi.
Found good synergy between kratom and harmalas (changa wise), but be careful please as Tramadol (for example) is listed as contraindicated meds for inhibited MAO (aya - pharma).

Yeah i once vaped a bit of DMT, a good dose, while on tramadol .. it was way too intense .. tramadol is also a serotonin reuptake inhibitor and I wonder if it reacts with DMT since DMT is a cousin to it [[ serotonin ]] .. isn't it?
But these days the only opiate I ever partake in once in a while is poppy seed tea, thats it
I may get some kratom just to see how it feels after being off suboxone and all the harder opiates
But yeah, caution is definitely needed when using tramadol with an MAOI however it may also be extreme even without maoi inhibition and just the two as they are..thats how it was for me and I never combined them ever again

In general, an SRI will diminish the effects of a 5-HT2A agonist by increasing the amount of synaptic 5-HT available to competitively bind to the active site of the target receptor.

If I had to take a shot in the dark, I'd hazard that maybe the increase in intensity may be a result of NMDAr antagonism, but tramadol has a pretty broad binding profile and hits most of the major neurotransmitter systems, so it really could be anything (or a variety of things).

Blessings
~ND