I was wondering, since Harman and Norharman are found in Coffee (though the amounts are probably low), would one be able to use larger amounts of decaffeinated Coffee to get reasonable MAO inhibition, or would the amounts even in a strong brew not be enough? Since there wouldn't be much Caffeine, i would think it'd be worth a try.

Would a high enough dose of decaffeinated Coffee possibly be able to orally activate DMT? (seeing as how Harman and Norharman inhibit MAO-A, while Norharman also is said to inhibit MAO-B, though i'm not sure how much). If not, would one be able to try an extraction on the decaffeinated Coffee, using vinegar and washing soda (like with Rue), to precipitate out the Harman and Norharman?

Thanks

I'm no expert on the subject by any means but after some searching around I think I figured this out.

According to:

https://www.deepdyve.com...e-substitutes-8GhBQlgaIC

And:

http://www.ncbi.nlm.nih.gov/pubmed/17291006

Most coffee seems to have very tiny amounts of harman and norharman in it that is produced mostly in the roasting process. We're talking 0.01% at absolute best by weight.

Conversely:

https://www.erowid.org/p.../syrian_rue_basics.shtml

Told me that rue seeds are anywhere from 2-7% weight by volume of harman, norharman, harmalol, and tetrahydroharmine. If you can get rue it's definitely cheap compared to many alternatives. From my estimates you'd be broke by the time you bought enough coffee to have a respectable amount of MAOIs.

That's not to say it's impossible to do. Just not a worthy investment of time and money. Enjoy a cup of coffee instead.

Edit:

I read some more. According to:
https://www.erowid.org/l...a/aya_sec1_dosages.shtml
It says that 120mg is the minimum amount of harmine base to activate oral dmt.

So for coffee at 0.01% you'd need a around 1000 grams, over 2 pounds, of coffee for a single minimum dose.