I'm interested in hearing what others have to say about using Aya/Pharma regularly as a form of self-medication/therapy. I myself have noticed quite a few benefits to using this stuff quite regularly to help stabilize my mental and physical health. I myself have high functioning Autism and notice that it helps me out neurochemically and hormonally during the experience, and in my daily life i seem to be feeling better, healthier and clearer. Has anyone else went down this road as well?

I find pharma and to a lesser extent changa to be very rejuvinitating and healing experiences. For up to two weeks after 250mg harmine/harmaline and 100mg DMT I am significantly higher functioning. This mostly comes from reduced stress and frustration. I feel like these positive effects would be increased and extended in duration if I were to dose higher but I do not feel it is necessary. For many people a significant Aya experience can leave them rejuvinated and "clear" for years. I am a psychedelic hard-head at this point so it is very hard for me to experience such long lasting effects but occasional doses of MAOI/DMT are still very helpful in a very broad sense. Depending on what you seek/expect YMMV.

Something like this.

I feel protected against the typical mundane forces that wears one out to a low energy state.

I am preparing to take daily doses of up to 20-40mg to enhance my mood and sensory perceptions. I find though that even just after one 30mg dose I sometimes see the subtle dmt-candyland perceptions weeks after the dose but just every now and again when I stare in to the forms of sight I see, never in an uncomfortable way yet but I imagine if I took larger doses maybe the flashbacks could be annoying or intolerable in someway. Subtle candyland appears as if the tones are very uniform and colors are more in contrast with one another and stand out more, it looks cartoonish basicly but in a more gentle, creative and passive way than say micky mouse or the simpsons.

I found that it is the MAOI that gives the lingering flashes... Before switching from vaporizing to oral MAOI aya/pharma I never got subtle candyland flashbacks.

I think from a health perspective, something that you really need to take into account for is going to be side effects of repetitive purging. There can be a range of negative side effects including the corrosion of your teeth, damage to the esophagus, pulling abdominal muscles and losing weight (this is not something you want to take advantage of ). You want to make sure you're getting all your meals in every day to stay healthy, and if you're anything like me, that just might not happen on days you take aya/pharma. When taken infrequently, it's not really a big deal, and none of these side effects are likely to show, but the more regular the procedure is, the more possibility there is for these effects to snowball.

The effects will indeed snowball. This makes it hard to microdose Aya/pharma on a daily basis. Last report I read a guy was experiencing cumulative effects from daily microdoses that eventually had him phasing in and out of hyperspace at inopportune places.

Wondering what people still call a microdose

Here is the thread I was referring to.

https://www.dmt-nexus.me...aspx?g=posts&t=50910

But Warrior said in that thread that he adjusted the dosage/ratio of harmalas to DMT (by simply adding more harmalas IIRC) and that smoothed things out.

Just takes experimentation; trial and error. He's had great success with it.

(though ShamensStamen, you didn't say anything about microdosing so this may not be what you were talking about but either way you'd probably find Warrior's thread that FLeP linked to very interesting.)

I myself have noticed with Rue one tends to get used to the purge (as in the purge seems to go away after awhile), also with Moclobemide there is no purge so one can use the DMT but not purge. I've also noticed some weight loss just from using the DMT with Moclobemide, i think it has to do with the Adrenaline or something.

Good info so far.

I myself use mainly low to moderate doses, high doses are for special occasions. I find Changa to be interesting, but not as fully medicinal as oral Aya/Pharma.

The thing about using Rue regularly, is the reverse tolerance. I still haven't figured out how to properly lower the Rue dose as the reverse tolerance gets stronger, which is why i've been using Moclobemide here lately.

As for flashbacks or sensory/perceptual anomalies, i haven't really experienced anything like that in my daily life since taking this stuff regularly. Though i have noticed if i smoke some Cannabis and listen to music, i can get some third eye visuals that accompany the music.

Moclobemide is not good for you, even though it is a more clear headed trip... it completely disrupts and even in some abolishes REM sleep which is vital to longterm memory encoding and most importantly general well being, as you know, no one likes the day after a messed up sleep!

The sleep disturbances seemed to be from the excess Norepinephrine that would normally get destroyed if it wasn't for the MAOI. I tried Clonidine which is a Norepinephrine antagonist and slept like a baby but it makes you very lethargic the day after. So if you are having trouble sleeping try something like a z-drug (nonbenzodiazapine) aswell as 5-htp, melatonin and valerian.

Syrian rue and Caapi somehow magicly swerve these negative side-effects and are very sleep inducing which is a mystery to me because they are both Reversable Inhibitors of MAOI

sleepermustawaken - Got the sleep thing covered, thanks though. I hear ya on the Clonidine, i've been on it before, it's got a long duration. Tizanidine though, is better and has a shorter duration. I also take about 15mgs of Melatonin, and sometimes some Robaxin. Robaxin and Tizanidine though are apparently rough on the liver, so they say. Oh i also use Celastrus seed at night to increase REM sleep and increase vividness of dreams.

But yeah Moclobemide isn't that bad, it definitely gets the job done, though i much prefer the Rue/Harmalas if it weren't for the nausea and purge factor (but i've noticed the purge seems to subside after awhile with regular use, after it cleans you out) and Cannabis takes care of the nausea for the most part.

Maybe you could try to do the extraction, no nausea what so ever but extraction is time consuming! Thanks for celastrus, I will try it out.

Yeah i do Rue extractions and encapsulate the freebase extract, have even used pure Harmalas, depending on the dose, the purge is still there even with pure Harmalas.

But yeah, Celastrus seeds are pretty good, i only take about 10 of them, and they definitely help with dreams, fatigue and improve bowel movements.

How much are you taking? 100mg is supposedly enough for MAOI and I never got purges. You sure you did salt manske few times to get rid of nauseau gunk?

You may want to try the salt of harmine instead of bombing freebase. You can do this easily by dissolving the freebase in fresh hot lemon juice before you drink it. On the other hand some people are just sensitive to these drugs.

sleepermustawaken - I am taking 180mgs to 200mgs of the full spectrum freebase Rue extract. I haven't used pure Harmalas in awhile though so i can't remember the dose for that.

FLeP - I would do that, but the Rue/Pure Harmala tea, while not that bad, does taste quite bitter. I much prefer to encapsulate my extract, i just wish there were a way to make a powdery salt form of the full spectrum Rue extract.

I myself kinda like the full spectrum Rue extract, especially with Lemon Balm in the mix. But back when i used Pure Harmalas, the effect was still great, more clearheaded it seemed and took away some of the dirty bodily feelings, but at the same time it lacked some of the qualities i'm used to from the Rue. Both are still good, i'm just more of a full spectrum guy, for now.