Shamans have been mixing cactus with tropane alkaloids for centuries to potentiate the effects of the cactus.

That's really weird. It sounds like something went wrong. That goes against everyone else's reports on the combo. Everyone else found it potentiated the mescaline not diminished the effects. Are you sure you had mescaline? Maybe your seeds are not properly identified and are actually something else? What did the seeds look like?

SWIM says the mescaline was indeed mescaline - 0.5g from the same batch produce decent effects. As for the seeds, they came from a backyard grown Datura stramonium plant. The plant was identified as datura stramonium by a really trusted certified botanist. The seeds were almost a year old, SWIM does not know if they had gone bad. They did had an effect however, the negative diminished effect.

SWIM is wondering how many people have tried the combo (extracted mescaline datura seeds) and how many felt the potentiation. SWIM thinks that not som many people have reported the combo - he remembers another one however that did not find the combo amazing.

Does SWIY have a reliable reference for the traditional mix of cactus with tropanes by the shamans? Which tropane sources they use? Which tropanes are involved? At which ratios do they mix them?

There are bound to be people with different reactions to everything there is. That’s human nature.

I don’t know if old seeds would be any different. SWIM has never noticed any difference between fresh or old seeds. I doubt age had anything to do with it. It’s more likely SWIYs personal metabolism at play here.

Some people are very sensitive to these seeds. Maybe SWIY is one of them. That could explain the unusual reaction.

How do the same seeds effect SWIY if taken on their own at the same dosage?



Yes, one other person, who was apparently very sensitive to the seeds did not enjoy the experience. If the seed dosage is too high, the effect is not at all the same. He also took a large dose of mescaline. I know of about 20 people who've tried this combination and enjoyed it very much. Most used very low doses of mescaline, not 500 mg.

You want to try using the seeds on their own first. Try to find a dosage that only causes slight stimulation, slight euphoria, and an unusual feeling in the stomach for about 1 hour or so. If you feel dry mouth, blurred vision, mental effects of any kind, or any other effects other than what I’ve mention earlier, then the seed dosage is way too high.

When mixing with mescaline, use a small dose of mescaline. 500 mg sounds like too much mescaline.



Yes. Several books I have talk about mixing San Pedro with Brugmansia. This is a classic combination. I don’t recall the ratio of San Pedro to Brugmansia though. The drink from this combination is called Cimora.

Can SWIY elaborate on this? Did it increase the aphrodisiac effects of the mescaline?

Yes, for SWIM it increased the aphrodisiac effects quite a bit.

That is very intriguing and something I'll definitely have to try! I love the aphrodisiac effects of MDMA, but hate the comedown and I'm totally wrecked the next day. I don't experience that on mesc, so if I can replicate the good of MDMA without the bad, I will be a very happy camper!

Has anyone tried this at lower levels: say, just one DS seed, with a super, super-low dose of mescaline - say 50mg?

Sid, my mate, loves the idea of amplifying the m* experience and making it last longer for more people (once he's done the extraction) but has a deep-seated, and obviously irrational fear of even the smallest, provably and probably safe mini-dose of any datura compound.

Sensitivity, homeopathy, and paranoia don't combine well with deleriants, he says.

Yes, SWIM has sort of. He used 25 mg of mescaline and 3 Datura stramonium seeds. 25 mg of mescaline is not even detectable to SWIM, but with the 3 seeds it was as strong as 75-100 mg of mescaline! It was VERY NICE.

He never used less that 3 seeds. It will probably work, but not as well.

could you mention where you get you datura stramonium seeds from? I have a longheld fear of the plant and if i am to use it in this way i want to reduce the variables as much as is humaly possible. thanks.

What's peppermint tea's role in SWIY 69ron's combination? Just potentiation? ...But coffee/caffeine is more effective?

SWIM gets his from FV. It doesn't matter where you get them. Just make sure they are indeed Datura stramonium seeds and that you take about 3 or so, no more than 10 in a day and you'll be perfectly fine.



Peppermint? Are you talking about LSA usage? I’m confused.

SWIM was referring to SWIY's original post:



Guessing From SWIY's reaction, SWIM is thinking that the peppermint tea made little to no difference in the experience?

SWIM just happened to use peppermint tea. There’s nothing special about it (unless we’re talking about LSA). Normally he uses coffee.

Ah, okay. SWIM was just curious if it may have played any kind of role in the experience. Thanks for clarifying