Hi all

about 6 years ago while traveling I had complete renal failure caused either by a strong allergic reaction to something or it could be related to a genetic disease i've had since birth. I was on dialysis for about 1 year and then had a kidney transplant. I started using entheogens about a year before having kidney failure on a quite regular basis. When I was on Dialysis I used Mushrooms and ayahuasca every few months with no negative side effects and San Pedro twice. My first San Pedro experience was quite gentle with not much discomfort but the second time was very hard with lots of nausea/stomach cramps etc... After that experience I assumed that mescaline was harder than Mushrooms/Ayahuasca on the kidneys and never tried it again.

After the kidney transplant I discussed these plants with my doctor and he told me that not enough research has been done on these things but in theory if it won't harm any normal person's kidneys it probably won't harm mine but that if I decided to go there and something goes wrong it's on me... After a long time of weighing up everything and speaking to 2 more doctors I decided that it's worth trying and did an Ayahuasca ceremony... I did tests and everything was better than the previous test results... Since then i've used changa/mushrooms/ayahuasca on a semi-regular basis with no negative effects on my kidney (it's now 6 years post transplant)

Lately i've felt drawn to the gentleness of my first San Pedro experience again but i'm in a lot of doubt after my last experience with it 5 years ago... Does anyone know of anything that points to Mescaline being more taxing on the kidneys or could that nausea have been related to my stomach and that particular batch of tea?

I find this an interesting post as i myself have had 50% Kidney function since birth and am a frequent explorer with the plants. I have not experienced any negatives although i do get huge nausea, stomach cramps and purging on them all at times. Im pretty sure its just the medicine doing its work and nothing kidney related!!

I think that's just part of the san pedro experience. As awesome as raw plants are, there's a lot of crap in them that we don't need. A tea is better than eating straight cactus, but it doesn't surprise me that you had a physical reaction. You'd probably benefit from extracting the mescaline from the cactus and dosing it in a capsule. This is the only way I've experienced it and have never felt nauseated from mescaline alone. I recommend the 69ron tek.

i've tried the 69ron tech but got only about 400mg from 200g cactus... So maybe it's time to try figure out what I did wrong Icon how was your experience with the extracted mescaline?

Just curious if you you have tried any mescaline yet. I also have a transplant and am more concerned about interaction with the immunosuppressant drugs than anything.
Thanks!

P.S. I just signed up here and this is my first post.

Hi Tstevens which drugs are you on? When I discussed this with my doctor he told me that before I start really thinking of going down this path he wanted to get me off prograff and onto Rapamune. How long ago did you have the operation? I think it's also probably a good idea to wait a year at least after the surgery for everything to settle. I also don't take any steroids which might have a negative reaction with these substances. I had to take prednison for 6 months in the beginning which definitely had many mental and physical side effects.

Hey DN,

Thanks for the reply. I'm on Prograf and Cellcept. I am on prednisone also, but only 5mg.
I really have not side effects at all.

Just received the kidney 5-17-2014, so it's pretty new. I will probably hold off doing any experimentation unless I can verify it would be safe. There doesn't seen to be much info out there on it. I really don't want to bring it up with my nephrologist as I believe he thinks I'm a little on the odd side to begin with, and like most doctors, he seems to be pretty conservative.

Anyway, thanks again and good luck with the kidney !

tStevens when you see your nefrologist again ask him if there's any chance you could move from prograff to rapamune in the future. After a few years prograff starts damaging the kidney so it's like a double edged sword... I was very lucky to have found my nefrologist as he's extremely progressive and if there's something new that has been proven to work well he'll move there immediately... One thing he did tell me has been proven to help regulate the immune system is marijuana. Get a vaporizer or make edibles in stead of smoking if you ever go there as smoking with a broken down immune system can probably still do some damage.

Interesting topic! My girlfriend has a long term chronic liver disease...accending primary cholangitis. I have done a ton of research about the impact, if any, of these substances we celebrate so much and their impact on the liver. There is not much info out there, but I haven't been able to find any credible evidence that they are detrimental. I also would value others experience and research into possible organ impact of mescaline and mushrooms.

Hey I came across this topic and needed to post. I had a kidney transplant nearly 15 yrs ago and am at that stage in life where I really feel like I need to go and experience ayuasca. I am on prograf so it seems I need to get off that? Is this a definite? Also yous were safe not having the yellow fever vaccination? I've been so worried about my kidney I haven't been able to make a definite decision. Any info / advice would be much appreciated? Also did you have any problems with blood pressure? Thanks in advance