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Classic psychedelic use is associated with reduced psychological distress and suicidality in the US Options
 
Dead man
#1 Posted : 1/19/2015 4:09:27 AM

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I know it's the wrong forum, but I can't post in the news section yet. I hope this hasn't been posted before (I checked and I couldn't find anything.)

Abstract:
Mental health problems are endemic across the globe, and suicide, a strong corollary of poor mental health, is a leading cause of death. Classic psychedelic use may occasion lasting improvements in mental health, but the effects of classic psychedelic use on suicidality are unknown. We evaluated the relationships of classic psychedelic use with psychological distress and suicidality among over 190,000 USA adult respondents pooled from the last five available years of the National Survey on Drug Use and Health (2008–2012) while controlling for a range of covariates. Lifetime classic psychedelic use was associated with a significantly reduced odds of past month psychological distress (weighted odds ratio (OR)=0.81 (0.72–0.91)), past year suicidal thinking (weighted OR=0.86 (0.78–0.94)), past year suicidal planning (weighted OR=0.71 (0.54–0.94)), and past year suicide attempt (weighted OR=0.64 (0.46–0.89)), whereas lifetime illicit use of other drugs was largely associated with an increased likelihood of these outcomes. These findings indicate that classic psychedelics may hold promise in the prevention of suicide, supporting the view that classic psychedelics’ most highly restricted legal status should be reconsidered to facilitate scientific study, and suggesting that more extensive clinical research with classic psychedelics is warranted.


Full article attached of course Thumbs up.
He who sees the infinite in all things sees God. He who sees the ratio only sees himself only. -William Blake There is no natural religion.
People in the past never lived in ecological balance with nature, they died in ecological balance with nature -Hans Rosling
Nothing is something worth doing -Sphongle
 

Explore our global analysis service for precise testing of your extracts and other substances.
 
Dead man
#2 Posted : 1/19/2015 4:20:09 AM

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OK, I'm not right in the head, it has already been posted. Sorry...
I don't know how to delete the thread?
He who sees the infinite in all things sees God. He who sees the ratio only sees himself only. -William Blake There is no natural religion.
People in the past never lived in ecological balance with nature, they died in ecological balance with nature -Hans Rosling
Nothing is something worth doing -Sphongle
 
Nereus
#3 Posted : 1/19/2015 12:48:05 PM

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j̶̶a̶̶m̶̶m̶̶i̶̶n̶̶g̶̶ ̶̶t̶̶h̶̶e̶̶ ̶̶n̶̶e̶̶x̶̶u̶̶s̶̶ ̶̶w̶̶i̶̶t̶̶h̶̶ ̶̶c̶̶o̶̶p̶̶y̶̶/̶̶p̶̶a̶̶s̶̶t̶̶e̶̶ ̶̶p̶̶o̶̶s̶̶t̶̶s̶̶ ̶̶i̶̶s̶̶ ̶̶n̶̶o̶̶t̶̶ ̶̶a̶̶ ̶̶b̶̶r̶̶i̶̶g̶̶h̶̶t̶̶ ̶̶i̶̶d̶̶e̶̶a̶̶.̶̶.̶̶.̶̶i̶̶m̶̶e̶̶ ̶̶t̶̶h̶̶a̶̶t̶̶ ̶̶w̶̶o̶̶n̶̶'̶̶t̶̶ ̶̶g̶̶e̶̶t̶̶ ̶̶y̶̶o̶̶u̶̶ ̶̶c̶̶l̶̶o̶̶s̶̶e̶̶r̶̶ ̶̶t̶̶o̶̶ ̶̶y̶̶o̶̶u̶̶r̶̶ ̶̶p̶̶r̶̶o̶̶m̶̶o̶̶t̶̶i̶̶o̶̶n̶̶ ̶̶e̶̶i̶̶t̶̶h̶̶e̶̶r̶̶?̶

I̶̶'̶̶d̶̶ ̶̶t̶̶r̶̶y̶̶ ̶̶t̶̶o̶̶ ̶̶f̶̶o̶̶c̶̶u̶̶s̶̶ ̶̶o̶̶n̶̶ ̶̶a̶̶ ̶̶w̶̶e̶̶l̶̶l̶̶ ̶̶w̶̶r̶̶i̶̶t̶̶t̶̶e̶̶n̶̶ ̶̶i̶̶n̶̶t̶̶r̶̶o̶̶d̶̶u̶̶c̶̶t̶̶i̶̶o̶̶n̶̶ ̶̶e̶̶s̶̶s̶̶a̶̶y̶̶ ̶̶o̶̶r̶̶ ̶̶a̶̶n̶̶ ̶̶e̶̶x̶̶p̶̶e̶̶r̶̶i̶̶e̶̶n̶̶c̶̶e̶̶ ̶̶r̶̶e̶̶p̶̶o̶̶r̶̶t̶̶.̶̶.̶̶.̶̶t̶̶h̶̶i̶̶n̶̶g̶̶s̶̶ ̶̶t̶̶h̶̶a̶̶t̶̶ ̶̶a̶̶r̶̶e̶̶ ̶̶e̶̶s̶̶s̶̶e̶̶n̶̶t̶̶i̶̶a̶̶l̶̶ ̶̶f̶̶o̶̶r̶̶ ̶̶u̶̶s̶̶ ̶̶a̶̶n̶̶d̶̶ ̶̶y̶̶o̶̶u̶̶ ̶̶s̶̶o̶̶ ̶̶a̶̶s̶̶ ̶̶t̶̶o̶̶ ̶̶g̶̶e̶̶t̶̶ ̶̶a̶̶c̶̶q̶̶u̶̶a̶̶i̶̶n̶̶t̶̶e̶̶d̶̶ ̶̶e̶̶a̶̶s̶̶i̶̶e̶̶r̶̶.̶̶Y̶̶o̶̶u̶̶ ̶̶s̶̶h̶̶o̶̶u̶̶l̶̶d̶̶ ̶̶n̶̶o̶̶t̶̶ ̶̶s̶̶t̶̶r̶̶e̶̶s̶̶s̶̶ ̶̶t̶̶o̶̶o̶̶ ̶̶m̶̶u̶̶c̶̶h̶̶ ̶̶a̶̶b̶̶o̶̶u̶̶t̶̶ ̶̶b̶̶e̶̶i̶̶n̶̶g̶̶ ̶̶p̶̶r̶̶o̶̶m̶̶o̶̶t̶̶e̶̶d̶̶.̶̶.̶̶i̶̶t̶̶ ̶̶w̶̶i̶̶l̶̶l̶̶ ̶̶c̶̶o̶̶m̶̶e̶̶ ̶̶i̶̶n̶̶ ̶̶t̶̶i̶̶m̶̶e̶

̶W̶̶e̶̶l̶̶c̶̶o̶̶m̶̶e̶̶ ̶̶t̶̶o̶̶ ̶̶t̶̶h̶̶e̶̶ ̶̶N̶̶e̶̶x̶̶!̶

̶P̶̶e̶̶a̶̶c̶̶e̶̶.̶
 
Intezam
#4 Posted : 1/19/2015 1:07:52 PM

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Nereus wrote:
Confused j̶̶a̶̶m̶̶m̶̶i̶̶n̶̶g̶̶ ̶̶t̶̶h̶̶e̶̶ ̶̶n̶̶e̶̶x̶̶u̶̶s̶̶ ̶̶w̶̶i̶̶t̶̶h̶̶ ̶̶c̶̶o̶̶p̶̶y̶̶/̶̶p̶̶a̶̶s̶̶t̶̶e̶̶ ̶̶p̶̶o̶̶s̶̶t̶̶s̶̶ ̶̶i̶̶s̶̶ ̶̶n̶̶o̶̶t̶̶ ̶̶a̶̶ ̶̶b̶̶r̶̶i̶̶g̶̶h̶̶t̶̶ ̶̶i̶̶d̶̶e̶̶a̶̶.̶̶.̶̶.̶̶i̶̶m̶̶e̶̶ ̶̶t̶̶h̶̶a̶̶t̶̶ ̶̶w̶̶o̶̶n̶̶'̶̶t̶̶ ̶̶g̶̶e̶̶t̶̶ ̶̶y̶̶o̶̶u̶̶ ̶̶c̶̶l̶̶o̶̶s̶̶e̶̶r̶̶ ̶̶t̶̶o̶̶ ̶̶y̶̶o̶̶u̶̶r̶̶ ̶̶p̶̶r̶̶o̶̶m̶̶o̶̶t̶̶i̶̶o̶̶n̶̶ ̶̶e̶̶i̶̶t̶̶h̶̶e̶̶r̶̶?̶

I̶̶'̶̶d̶̶ ̶̶t̶̶r̶̶y̶̶ ̶̶t̶̶o̶̶ ̶̶f̶̶o̶̶c̶̶u̶̶s̶̶ ̶̶o̶̶n̶̶ ̶̶a̶̶ ̶̶w̶̶e̶̶l̶̶l̶̶ ̶̶w̶̶r̶̶i̶̶t̶̶t̶̶e̶̶n̶̶ ̶̶i̶̶n̶̶t̶̶r̶̶o̶̶d̶̶u̶̶c̶̶t̶̶i̶̶o̶̶n̶̶ ̶̶e̶̶s̶̶s̶̶a̶̶y̶̶ ̶̶o̶̶r̶̶ ̶̶a̶̶n̶̶ ̶̶e̶̶x̶̶p̶̶e̶̶r̶̶i̶̶e̶̶n̶̶c̶̶e̶̶ ̶̶r̶̶e̶̶p̶̶o̶̶r̶̶t̶̶.̶̶.̶̶.̶̶t̶̶h̶̶i̶̶n̶̶g̶̶s̶̶ ̶̶t̶̶h̶̶a̶̶t̶̶ ̶̶a̶̶r̶̶e̶̶ ̶̶e̶̶s̶̶s̶̶e̶̶n̶̶t̶̶i̶̶a̶̶l̶̶ ̶̶f̶̶o̶̶r̶̶ ̶̶u̶̶s̶̶ ̶̶a̶̶n̶̶d̶̶ ̶̶y̶̶o̶̶u̶̶ ̶̶s̶̶o̶̶ ̶̶a̶̶s̶̶ ̶̶t̶̶o̶̶ ̶̶g̶̶e̶̶t̶̶ ̶̶a̶̶c̶̶q̶̶u̶̶a̶̶i̶̶n̶̶t̶̶e̶̶d̶̶ ̶̶e̶̶a̶̶s̶̶i̶̶e̶̶r̶̶.̶̶Y̶̶o̶̶u̶̶ ̶̶s̶̶h̶̶o̶̶u̶̶l̶̶d̶̶ ̶̶n̶̶o̶̶t̶̶ ̶̶s̶̶t̶̶r̶̶e̶̶s̶̶s̶̶ ̶̶t̶̶o̶̶o̶̶ ̶̶m̶̶u̶̶c̶̶h̶̶ ̶̶a̶̶b̶̶o̶̶u̶̶t̶̶ ̶̶b̶̶e̶̶i̶̶n̶̶g̶̶ ̶̶p̶̶r̶̶o̶̶m̶̶o̶̶t̶̶e̶̶d̶̶.̶̶.̶̶i̶̶t̶̶ ̶̶w̶̶i̶̶l̶̶l̶̶ ̶̶c̶̶o̶̶m̶̶e̶̶ ̶̶i̶̶n̶̶ ̶̶t̶̶i̶̶m̶̶e̶

̶W̶̶e̶̶l̶̶c̶̶o̶̶m̶̶e̶̶ ̶̶t̶̶o̶̶ ̶̶t̶̶h̶̶e̶̶ ̶̶N̶̶e̶̶x̶̶!̶

̶P̶̶e̶̶a̶̶c̶̶e̶̶.̶

Smile Why? We liked it....Thumbs up
 
Nereus
#5 Posted : 1/19/2015 1:18:27 PM

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Heh, pardon for being mean.Prejudices stand in the way of knowing.

I apologise for having a douche behaviour Love
 
Knarkkorven
#6 Posted : 1/19/2015 6:17:51 PM

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Thanks for posting this! Very interesting.

The results goes well with the other studies released in the past few years, indicating less mental illness.
Like this from 2013:

Quote:

Psychedelics and Mental Health: A Population Study

Background

The classical serotonergic psychedelics LSD, psilocybin, mescaline are not known to cause brain damage and are regarded as non-addictive. Clinical studies do not suggest that psychedelics cause long-term mental health problems. Psychedelics have been used in the Americas for thousands of years. Over 30 million people currently living in the US have used LSD, psilocybin, or mescaline.
Objective

To evaluate the association between the lifetime use of psychedelics and current mental health in the adult population.

Method

Data drawn from years 2001 to 2004 of the National Survey on Drug Use and Health consisted of 130,152 respondents, randomly selected to be representative of the adult population in the United States. Standardized screening measures for past year mental health included serious psychological distress (K6 scale), mental health treatment (inpatient, outpatient, medication, needed but did not receive), symptoms of eight psychiatric disorders (panic disorder, major depressive episode, mania, social phobia, general anxiety disorder, agoraphobia, posttraumatic stress disorder, and non-affective psychosis), and seven specific symptoms of non-affective psychosis. We calculated weighted odds ratios by multivariate logistic regression controlling for a range of sociodemographic variables, use of illicit drugs, risk taking behavior, and exposure to traumatic events.

Results

21,967 respondents (13.4% weighted) reported lifetime psychedelic use. There were no significant associations between lifetime use of any psychedelics, lifetime use of specific psychedelics (LSD, psilocybin, mescaline, peyote), or past year use of LSD and increased rate of any of the mental health outcomes. Rather, in several cases psychedelic use was associated with lower rate of mental health problems.
Conclusion

We did not find use of psychedelics to be an independent risk factor for mental health problems.

Psychedelics and Mental Health: A Population Study

 
VoidTJ
#7 Posted : 1/19/2015 6:33:53 PM

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Psychedelics are indeed great for mental issues.

I don't think EVERYONE suffering mental problems should use psychedelics of course but those that know they can handle them but are experiencing depression or other problems should definitely consider them.

So far DMT has helped me kick my heroin/oxy problem which indirectly lessened my problems but beyond that I have been one that always hated life. Time after time I wanted to end it. I'm really not sure why... The only reason I never did was because I had a conscious and could not be that selfish/harm my family in that way.

It took a while and a LOT of fights with myself/hyperspace but over time, DMT truly helped me out of that morbid haze. Whereas before I hated waking up in the morning (I still do, but just because I have to work Very happy) I'm not necessarily Mr. Happy-Go-Lucky but I do appreciate things a lot more and I've come to realize just how blessed/lucky/whatever I have been over the years.

Further, once you see the wonder beyond the veil, it's hard not to be excited about life's little mysteries Smile.

Good share.
 
Spiralout
#8 Posted : 1/19/2015 9:12:47 PM

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Thank you for sharing this ! Thumbs up

I have seen psychedelics seemingly have a positive impact on myself and others. No clinical evidence of that of course but it seems pretty clear to me that they can be beneficial.

Careful with the swearing, it isn't allowed ! Love
 
EternalPeace
#9 Posted : 1/19/2015 11:52:07 PM
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I wonder if this has something to do with serotonin?
 
null24
#10 Posted : 1/20/2015 1:19:43 AM

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I feel very comfortable saying that within the near future, huge advances toward successful treatment of many disorders that are common ills now will be realized with the help of psychedelics. These substances display obvious beneficial properties that are incredibly useful for these things, each one to their own efficacy. The lifting of prohibitions on studies is lifting the fog of disinformation and ignorance that has surrounded them since the 60's. I feel that we will look back at pre legalization as the cognitive dark ages with a collective shame.
Sine experientia nihil sufficienter sciri potest -Roger Bacon
*γνῶθι σεαυτόν*
 
Varni
#11 Posted : 1/20/2015 1:34:11 AM

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Psilocybin has been proving to be greatly effective in treating things like depression, anxiety, and even PTSD. I've heard that micro-dosing psilocybin on a regular basis has a lot of benefits but can't seem to find much in the way of formal studies, but there is a great deal of anecodotal evidence, and formal studies which report findings to support the hypothesis. Here's a related article from Discovery: http://news.discovery.co...ms-depression-122301.htm
A naked man fears no pickpocket.
 
Dead man
#12 Posted : 1/20/2015 3:08:20 AM

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VoidTJ wrote:
Psychedelics are indeed great for mental issues.

I don't think EVERYONE suffering mental problems should use psychedelics of course but those that know they can handle them but are experiencing depression or other problems should definitely consider them.


Agreed and I'm not surprised they can have a positive impact, especially when compared to other drugs. They can recall a sense of awe and beauty in nature to those that have lost it, and they bring up repressed memories which is great for therapy. In my experience they can also do the exact opposite of relieving depression however especially with bad set/setting. e.g feelings of insignificance, realizations that this world is not real, alienation from no longer being on the same level as others around you etc. For these reasons psychedelics are not a magic bullet and care should be taken to create a proper set/setting. This is why I think they should be legalized at the very least in psychotherapy where a proper environment can be created and support can be given. This is also why forums like dmt nexus are so important.
He who sees the infinite in all things sees God. He who sees the ratio only sees himself only. -William Blake There is no natural religion.
People in the past never lived in ecological balance with nature, they died in ecological balance with nature -Hans Rosling
Nothing is something worth doing -Sphongle
 
Dead man
#13 Posted : 1/20/2015 4:12:07 AM

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Varni wrote:
Here's a related article from Discovery: http://news.discovery.co...ms-depression-122301.htm

I attached the two studies mentioned in the article for those interested in reading more.

Nereus wrote:
Confused jamming the nexus with copy/paste posts is not a bright idea...ime that won't get you closer to your promotion either?Neutral

I'd try to focus on a well written introduction essay or an experience report...things that are essential for us and you so as to get acquainted easier.You should not stress too much about being promoted..it will come in time.

Welcome to the Nex!

Peace.

Thanks for the welcome! I didn't mean to double post...
He who sees the infinite in all things sees God. He who sees the ratio only sees himself only. -William Blake There is no natural religion.
People in the past never lived in ecological balance with nature, they died in ecological balance with nature -Hans Rosling
Nothing is something worth doing -Sphongle
 
obliguhl
#14 Posted : 1/20/2015 4:57:14 PM

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Thanks for taking the Initiative to post this Smile
 
null24
#15 Posted : 1/21/2015 12:20:34 AM

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Varni wrote:
Psilocybin has been proving to be greatly effective in treating things like depression, anxiety, and even PTSD. I've heard that micro-dosing psilocybin on a regular basis has a lot of benefits but can't seem to find much in the way of formal studies, but there is a great deal of anecodotal evidence, and formal studies which report findings to support the hypothesis. Here's a related article from Discovery: http://news.discovery.co...ms-depression-122301.htm



A couple years ago, i was able to forage a large amount of ps cyanescens, and for close to a year, regularly micro dosed. I would eat a stern or a cap, barely above threshold dose, once every two weeks. It gave me the happiest, most productive year of recent memory.

The mood stabilization was noticeable and my depression was markedly improved. Yay mushrooms!
Sine experientia nihil sufficienter sciri potest -Roger Bacon
*γνῶθι σεαυτόν*
 
Dead man
#16 Posted : 1/21/2015 6:29:22 AM

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Another one (January 16 2015)
Long-term use of psychedelic drugs Is associated with differences in brain structure and personality in humans.
Quote:
Psychedelic agents have a long history of use by humans for their capacity to induce profound modifications in perception, emotion and cognitive processes. Despite increasing knowledge of the neural mechanisms involved in the acute effects of these drugs, the impact of sustained psychedelic use on the human brain remains largely unknown. Molecular pharmacology studies have shown that psychedelic 5-hydroxytryptamine (5HT)2A agonists stimulate neurotrophic and transcription factors associated with synaptic plasticity. These data suggest that psychedelics could potentially induce structural changes in brain tissue. Here we looked for differences in cortical thickness (CT) in regular users of psychedelics. We obtained magnetic resonance imaging (MRI) images of the brains of 22 regular users of ayahuasca (a preparation whose active principle is the psychedelic 5HT2A agonist N,N-dimethyltryptamine (DMT)) and 22 controls matched for age, sex, years of education, verbal IQ and fluid IQ. Ayahuasca users showed significant CT differences in midline structures of the brain, with thinning in the posterior cingulate cortex (PCC), a key node of the default mode network. CT values in the PCC were inversely correlated with the intensity and duration of prior use of ayahuasca and with scores on self-transcendence, a personality trait measuring religiousness, transpersonal feelings and spirituality. Although direct causation cannot be established, these data suggest that regular use of psychedelic drugs could potentially lead to structural changes in brain areas supporting attentional processes, self-referential thought, and internal mentation. These changes could underlie the previously reported personality changes in long-term users and highlight the involvement of the PCC in the effects of psychedelics.

Covers ayahuasca!

Link to new thread: https://www.dmt-nexus.me...aspx?g=posts&t=62653
He who sees the infinite in all things sees God. He who sees the ratio only sees himself only. -William Blake There is no natural religion.
People in the past never lived in ecological balance with nature, they died in ecological balance with nature -Hans Rosling
Nothing is something worth doing -Sphongle
 
Varni
#17 Posted : 5/18/2015 8:27:38 PM

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null24 wrote:
Varni wrote:
Psilocybin has been proving to be greatly effective in treating things like depression, anxiety, and even PTSD. I've heard that micro-dosing psilocybin on a regular basis has a lot of benefits but can't seem to find much in the way of formal studies, but there is a great deal of anecodotal evidence, and formal studies which report findings to support the hypothesis. Here's a related article from Discovery: http://news.discovery.co...ms-depression-122301.htm



A couple years ago, i was able to forage a large amount of ps cyanescens, and for close to a year, regularly micro dosed. I would eat a stern or a cap, barely above threshold dose, once every two weeks. It gave me the happiest, most productive year of recent memory.

The mood stabilization was noticeable and my depression was markedly improved. Yay mushrooms!



I tried for a short period but needed more harvest to keep it up. Working on it now. I'm debating keeping a pretty strict record of it, as it could be used in further research. As a veteran with somewhat severe PTSD and anger issues, should it prove to be effective on me, it should work wonders for most other people lol.
A naked man fears no pickpocket.
 
oversoul1919
#18 Posted : 5/18/2015 8:58:26 PM

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Joined: 02-Aug-2014
Last visit: 14-Sep-2024
As someone said, not everyone with mental health problems should use psychedelics. Or with other disorders too. What would happen to person with photosensitive epilepsy taking breakthrough dose of DMT? I can only imagine.

This is great paper, and I'm glad that there are studies like this. Keep 'em coming, docs. Smile
 
 
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