Dude--RESEARCH.
I'm sorry, but there are two solid threads on this.
The answer to your question is yes. Some have had tremendous success, some however have had mixed success, and some no success. Follow the threads though. There's some awesome information in them.
All of my posts are entirely fictional. I am a writer, and as a means to research the life of a fictional character that I'm writing about, I post on the Nexus to get into character. In real life I have no interest or interaction with mind-altering substances.