Mugwort is a classic term for many different cultivars of artemisia.. so it depends which one you are using. All mugworts contain
thujone.. which can be therapeutic, toxic, or even deadly in high doses. Its effect on ayahuasca is unknown, afaik. Mugwort is a mild plant anyways, so I don't see much additional effect.. the interactions are unknown, afaik. I cannot report an experience with combining these two plants, however there are most likely reports of Nexians using mugwort as a base for 'changa,' in which it may provide comforting, calming effects, and also reduce negative effects such as nausea or dizziness.
'What's going to happen?' 'Something wonderful.'
Skip the manual, now, where's the master switch?
We are interstellar stardust, the re-dox co-factors of existence. Serve the sacred laws of the universe before your time comes to an end. Oh yes, you shall be rewarded.