Well for the mushrooms I used small doses in the afternoons, once in the morning which was cool but not something I will do often. Doses were always two grams or less, sometimes just half grams to limber up the mind. As far as DMT goes I was all over the map dose wise. I find that enhanced leaf works best and easiest for me. The Changa was my favorite but I think it was giving me headaches. I was still on pills then though. I've been using a 1/1 enhanced mullein leaf since but will try Changa again soon. I usually load about 100mg leaf in my steam roller, I like to have a small hit first and wait for it to fade a bit, then take another bigger one or two, this way is more relaxing than one big hit, less scary. So its about 50mg actives usually. The Pedro was an extract I made not following any recipe, it was over three feet of cactus extracted and reduced down to two ounces in grain alcohol. I sampled half of it on Halloween and was shocked at how strong it was, and at how long it lasted. I had used Pedro cactus in the past but it was never so awesome as this time. I was mostly alone that night and it was good but I felt like I could have talked someones ear off . Also my jaw was sore the next day.