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Brazilian Scientist: Ayahuasca/DMT Can Effectively Treat Cancer Options
 
MultiDimensionalTherapy
#1 Posted : 11/4/2014 12:54:03 PM

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I will copy the article integrally below. i would like your opinion about this.
im a little bit skeptical about this, mostly bcause how they conducted the article, but ive taken aya many times when i was sick, and it allways helped a lot. but it seems to me that most of the healing effect comes from the vine, oposed to the idea of the article that is DMT the responsible for that.
how far do you think that the healing effects of ayahuasca can go?



Eduardo Schenberg, of the University of Sao Paulo, Brazil, recently published a piece in Sage Journals, detailing his belief that Ayahuasca has cancer-fighting abilities, essentially encouraging the legalization of research in the field.

He says, “There is enough available evidence that Ayahuasca’s active principles, especially DMT and harmine, have positive effects in some cell cultures used to study cancer, and in biochemical processes important in cancer treatment, both in vitro and in vivo,” and “Therefore, the few available reports of people benefiting from Ayahuasca in their cancer treatment experiences should be taken seriously, and the hypothesis presented here, fully testable by rigorous scientific experimentation, helps to understand the available cases and pave the way for new experiments.”

“In summary, it is hypothesized that the combined actions of β-carbolines and DMT present in Ayahuasca may diminish tumor blood supply, activate apoptotic pathways, diminish cell proliferation, and change the energetic metabolic imbalance of cancer cells, which is known as the Warburg effect,” Schenberg wrote. “Therefore, Ayahuasca may act on cancer hallmarks such as angiogenesis, apoptosis, and cell metabolism.”

“If Ayahuasca is scientifically proven to have the healing potentials long recorded by anthropologists, explorers, and ethnobotanists, outlawing Ayahuasca or its medical use and denying people adequate access to its curative effects could be perceived as an infringement on human rights, a serious issue that demands careful and thorough discussion.”

Similar to the way cancer has been successfully treated with cannabis oil, or vitamin B-17 from the apricot pit, it is emerging as a viable possibility that Ayahuasca is another herbal, ancient cure to disease found in abundance in the new world of synthetic consumption.

Ayahuasca, as many viewers of this article likely know, is a psychoactive, ancient, sacred ancient brew, with deep roots in South American shamanic practice. Since at least 500 BC, South American shamans have used Ayahuasca for ceremonial purposes, and as a medicine of many functions.

Many people believe that DMT is created in the pineal gland of human beings when we dream, when we are born, and when we die. Critics of this theory say there is no evidence to back up these claims, but as of 2013, studies from the University of Michigan have shown that indeed dimethyltryptamine is created in the pineal glands of rats, and with the biological similarities us mammals share, it is very likely that DMT is synthesized in our pineal glands as well. According to Dr. Rick Strassman, author of the critically acclaimed book DMT- The Spirit Molecule, the human body metabolizes DMT rapidly, almost eager to consume the substance. Seretonin, the primary source of pleasure for us human beings, created in our brains and bodies daily of course, is 5-hydroxytryptamine, almost chemically identical to dimethyltryptamine. Yet, the US government classifies this molecule that may be part of our very being, as a schedule I, highly illegal drug.

DMT is a very complex substance, with complex experiences had by those who consume it, complex origins, and many, many functions. One must do their own hard research on Ayahuasca and DMT, as explaining a good depth of it would be too much for this article. Many of you who have read this far, probably already know what you need to know about Ayahuasca/DMT, as the popularity of it is skyrocketing.

Adam Winstock, founder of the Global Drugs Survey, claims the drug has ‘a larger proportion of new users’ compared to these other powerful drugs.

He says this suggests ‘its popularity may increase’.

It should be noted that Ayahuasca/DMT has characteristics similar to almost no ‘drugs’ except perhaps psilocybin mushrooms. Psilocin (what psilocybin metabolizes into), is also almost identical to chemicals already in our brains, similarly metabolized quickly by the body, more characteristic of a vitamin than an intoxicant.

For the viewers of this piece who do not already know, Ayahuasca is a brew consisting of many different psychoactive plants, including dimethyltryptamine containing foliage, and MAOI inhibiting plants that make the DMT active when ingested orally, namely the root bark of the Caapi vine. Caapi root bark contains monoamine oxidase inhibitors, harmala alkaloids. The DMT in Ayahuasca is primarily found in the leaves of the Psychotria Viridis plant, or the seeds of Syrian Rue, or both. Similar to cannabis’ ancient, rich history as a medicine, Ayahuasca has been a fundamental part of indigenous cultures in South America, namely the Amazonian rainforest and Peru, for thousands of years.

Ayahuasca is not typically looked at as a tool to treat cancer. More often, people decide to drink Ayahuasca or ingest DMT in pursuit of life-changing experiences, epiphanies, to visit unexplored corners of the mind, in hopes of easing a wide range of psychological ailments and problems.

More often than not, people who consume Ayahuasca/DMT report extreme mental clarity after the experience, a difficult-to-explain sense of well-being, as if the substances organized the user’s subconscious and rarely touched areas of the brain.

It seems that simultaneously with all the other ways we are seeing a global paradigm shift, there is a shift taking place in the realm of medicine. After about a century of criminalizing plants and mind-altering products of the earth, people globally seem to be taking great interest in the Earth’s treasure chest of medicine in botany and nature, no longer concealed from us or alleged to be dangerous by proponents of pharmaceutical monopolies. Scientists such as Eduardo Schenberg will surely press on in their work, as the massive surge in popularity for these things grows exponentially. If you skipped the part of this article in which I explained the basics of Ayahuasca/DMT because you are already familiar with it, you are likely part of this very paradigm shift.

As could go without saying, more research and uninhibited analysis of Ayahuasca’s effect on human beings is necessary to understand the effectiveness of it as a treatment for cancer and who knows what else. The World Wide Web increasingly seems to push truths to the surface of the minds of those who pay attention, while false info can quickly debunked with little effort. This is the paradigm of our world in 2014.
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MultiDimensionalTherapy
#2 Posted : 11/4/2014 12:57:55 PM

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because i would have to put all the reference links with the anonym, and im lazy right now, i will just put the link to the article, and you can check the references in the end

article link
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Ufostrahlen
#3 Posted : 11/4/2014 4:03:42 PM

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Quote:
Ayahuasca and cancer treatment

Results:
At least nine case reports regarding the use of ayahuasca in the treatment of prostate, brain, ovarian, uterine, stomach, breast, and colon cancers were found. Several of these were considered improvements, one case was considered worse, and one case was rated as difficult to evaluate. A theoretical model is presented which explains these effects at the
cellular, molecular, and psychosocial levels. Particular attention is given to ayahuasca’s pharmacological effects through the activity of N,N-dimethyltryptamine at intracellular sigma-1 receptors. The effects of other components of ayahuasca, such as harmine, tetrahydroharmine, and harmaline, are also considered.

http://smo.sagepub.com/c...2113508389.full.pdf+html
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Cognitive Heart
#4 Posted : 11/4/2014 8:56:15 PM

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Considering the entire chemical make-up of DMT-containing plants.. I am not surprised. Pleased
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expandaneum
#5 Posted : 11/4/2014 10:18:25 PM

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pfff where to begin...

this imo is grasping at straws, supporting ideas with research that cannot be translated one on one, for example the part where "positive effects" from dmt on cell cultures scales to dmt human scale.

Also the part that we can scale the results of rats pineal glands to mans pineal glands is very far far-fetched.

And then the notion of dmt being a complex substance, by what standards ? chemically its a very simple substance.

and this go's on and on

Quote:
Cancer doesn't like alkaline environments.

@ spiritofspice
I don't think cancer thinks, or likes, so do you have some articles to back up your claims ?
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anrchy
#6 Posted : 11/5/2014 12:23:52 AM

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From what i understand what you ingest cannot directly effect any lasting blood ph levels otherwise you would have acidosis. The whole alkaline diet thing includes food that is rrally good for you but that is where it ends.
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#7 Posted : 11/5/2014 2:09:40 AM

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expandaneum wrote:
pfff where to begin...

this imo is grasping at straws, supporting ideas with research that cannot be translated one on one, for example the part where "positive effects" from dmt on cell cultures scales to dmt human scale.

Also the part that we can scale the results of rats pineal glands to mans pineal glands is very far far-fetched.

And then the notion of dmt being a complex substance, by what standards ? chemically its a very simple substance.

and this go's on and on

Quote:
Cancer doesn't like alkaline environments.

@ spiritofspice
I don't think cancer thinks, or likes, so do you have some articles to back up your claims ?


I don't think it is grasping at straws particularly to say that harmala alkaloids and DMT have anticancer effects that are translatable to humans. There are numerous studies detailing some of the many complex actions of these molecules against tumors and cancer. Both DMT, and Harmalas have been shown to act at the Sigma receptors, which have been implicated in cancer and regulation. The beta-carbolines have also been shown to inhibit angiogenesis. Cell lines are how most studies go when exploring a new drug before headed to in vivo experiments, and while you can't extrapolate a cell line to a whole person, it does provide evidence that would reasonable warrant further investigation.

I've attached the Ayahuasca review that it is quoted. There are more out there if you search for a moment. I'm just not sure what you're shrugging off?
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expandaneum
#8 Posted : 11/5/2014 9:26:51 AM

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I read the first paper, and i do think that more research is needed to say that aya does not cure cancer.

This quote says it all
Quote:
In 2010, a peer-reviewed study was published investigating people who tried ayahuasca as a treatment for different illnesses, including cancer.3 Four cancer patients were identified: a 59-year-old man with prostate cancer, a 40-year-old woman with uterine cancer, a 36-year-old woman with benign uterine myoma, and a 43-year-old woman with stomach cancer. The study does not include many details about each patient, but the inclusion criteria “included a professionally diagnosed disorder by a medical expert.”3 The prostate cancer case was rated as “no effect,” the uterine cancer case was labeled a “complete recovery,” the uterine myoma case was determined to be “worse,” and the stomach cancer case was “unratable” because the patient reported feeling the remission of her cancer but refused to undergo medical examinations.


These are 4 of the 9 cases reviewed the others are much more questionable of quality.

Then the author concludes this.
Quote:
In conclusion, the data available so far is not sufficient to claim whether ayahuasca indeed helps in cancer treatment or not.


Exactly what I think too.


Finally I do believe that aya can have a positive effect on the mental well being of humans in general and this includes cancer patients.

Also the first paper is published in a journal with no impact factor. This to me is generally a sign of less rigorous review processes and therefore of lower scientific quality.
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MultiDimensionalTherapy
#9 Posted : 11/5/2014 2:15:30 PM

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i think that probably the fact that there was an improvement on cancer patients can come from the positive mental effects that can come with the experience itself, and not only the substance or the actives in it. if you look at healing in an holistic way, healing the psyche is an important step to achieve the healing of the body.

and having experienced some strong diets, it seems to me that its very important that you make the diet, abstaining from specific foods, toughts and ambients that are not healty, and also consume during the diet good amounts of specific plants/herbs, that will work together with ayahuasca.
not only some herbs increase the healing capability of ayahuasca, as also ayahuasca enhances the properties from this other plants.

@Spiritofspice

i tought that being so acidic, ayahuasca would lower the ph of urine. but i have a similar experience vaping DMT, i had a tuberculosis some years ago, and it really improved my healing rate, since tuberculosis also likes acidic enviroments, and freebase spice is very alkaline.

but anyway, if its a matter of ph, i think that the credit should not be given to the plants themselves, since you can use basicly anything for this effect. i remember meeting some people talking like crazy about some Miracle Mineral Solution or something like that, and it was just sodium chlorite neutralized by citric acid, wich i personaly wouldn't ingest.
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#10 Posted : 11/5/2014 5:40:03 PM

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MultiDimensionalTherapy wrote:

@Spiritofspice

i thought that being so acidic, ayahuasca would lower the ph of urine. but i have a similar experience vaping DMT, i had a tuberculosis some years ago, and it really improved my healing rate, since tuberculosis also likes acidic environments, and freebase spice is very alkaline.



Mycobacterium Tuberculosis is an intracellular pathogen (in macrophages); the bug can tolerate a pH down to 4.5 and survive; I'm not sure that freebase spice affects the pH within macrophages.
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#11 Posted : 11/5/2014 6:19:24 PM

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expandaneum wrote:
I read the first paper, and i do think that more research is needed to say that aya does not cure cancer.

This quote says it all
Quote:
In 2010, a peer-reviewed study was published investigating people who tried ayahuasca as a treatment for different illnesses, including cancer.3 Four cancer patients were identified: a 59-year-old man with prostate cancer, a 40-year-old woman with uterine cancer, a 36-year-old woman with benign uterine myoma, and a 43-year-old woman with stomach cancer. The study does not include many details about each patient, but the inclusion criteria “included a professionally diagnosed disorder by a medical expert.”3 The prostate cancer case was rated as “no effect,” the uterine cancer case was labeled a “complete recovery,” the uterine myoma case was determined to be “worse,” and the stomach cancer case was “unratable” because the patient reported feeling the remission of her cancer but refused to undergo medical examinations.


These are 4 of the 9 cases reviewed the others are much more questionable of quality.

Then the author concludes this.
Quote:
In conclusion, the data available so far is not sufficient to claim whether ayahuasca indeed helps in cancer treatment or not.


Exactly what I think too.


Finally I do believe that aya can have a positive effect on the mental well being of humans in general and this includes cancer patients.

Also the first paper is published in a journal with no impact factor. This to me is generally a sign of less rigorous review processes and therefore of lower scientific quality.



Right, Ok, I see you now. I agree that more evidence is needed to say ayahuasca can effectively treat or cure cancer. It seemed to me though that you were shrugging it all off as so improbable, when there are studies to attest to anticancer effects in cell lines (and I think there are studies with rats and Syrian rue, but I could be remembering wrong). I think it's sigma receptor action, and immunomodulatory effects are most interesting with regard to cancer, and the beta-carboline anti-angiogenic effects, given Syrian rue's ancient use in treating cancer. I'd just like to see more research. Cheers
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