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Harmine poisoning? Options
 
kemist
#1 Posted : 5/28/2009 2:32:49 AM

John


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Last visit: 27-Jan-2024
Location: Highland
ILpt has his breakfast this morning consistent off 2 hard boiled eggs two slices of brown bread with butter and cup of black tea with little milk

An hour or so after he ingested 400mg of harmine(isolated from rue)and splashed it down with cup of white coffee....

....20` after he noticed familiar buzz and effects start to develop

....but after another 40 mins he become dizzy and drowsy there was looping in his sight what gave him already mentioned "cybersickness" walking cause vertigo and stuff....

...he decided to purge and did so for 15 mins. he has to lay in to the bed to feel alright and not to be nauseous.

.... this become actually very nice apart ILPT didn`t wanna be incapacitated since he has job to do..

... never mind.... when hi shut his eylids they were geometric swirling patterns, and visuals consistent of faces, machines and others man-made thing well known by ILPT from the real world. Nothing unnatural ...

... those "visions" were strong for about an hour then faded away
....cybersickness lasted another three hours

... need to tell he has also OTC antiallergen medicine CETIRIZINE.HCl one pill of 10mg roughly 4-5 hours beforehand

What caused this nasty side effects of such a beautiful substance???
Tyramine in eggs? cetirizine? or simply OVERDOSE ? Wut?

........it wasn`t tea neither coffee, ILPT used them with sublingual harmine(up to 250mg)with great success

anyway he`s off to bed now as he has 150mg of harmaline sublingually (without any xanthines)and it making him sleepy now Cool
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 

STS is a community for people interested in growing, preserving and researching botanical species, particularly those with remarkable therapeutic and/or psychoactive properties.
 
coz42
#2 Posted : 5/28/2009 3:22:13 AM

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It could possibly be the purity of said product, and I'm quite positive that tyramine+MAO-A is not the cause of nausea.

Weighing at 75kg, taking around 250mg of rue extract genuinely puts me in that head space as harmaline is psychedelic at 100mg doses, as proven sublingually
In the end we will conserve only what we love. We will love only what we understand. We will understand only what we are taught. ~Baba Dioum
 
kemist
#3 Posted : 5/28/2009 2:57:31 PM

John


Posts: 700
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Last visit: 27-Jan-2024
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ILPT said there was no gorilla or other monkey business going on.Laughing
He will be soon of cetrizine medication and will go for high dose of both harmine and harmaline
....for here and now up to 250 mg sublingually is good way to go.
.... it was most likely overdose as there weren`t any impurities apart salt,CH3COONa,and little bit of Na2CO3
Cetrizine itself making him slightly dizzy sometimes and make his mouth dry all the time

dagger wrote:
I welcome the purging, as does many, if not most experienced ayahuasca users.
ILPT can`t imagine to have light as well and tripping hard whilst purguing. That`s why he never had ayahuasca Shocked but only fumohuasca or spice separately and maoi`s separately
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
acolon_5
#4 Posted : 5/28/2009 5:31:29 PM

The Great Namah


Posts: 3433
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Last visit: 17-Sep-2020
Location: The place entites go when they smoke allspice
kemist wrote:
ILpt has his breakfast this morning consistent off 2 hard boiled eggs two slices of brown bread with butter and cup of black tea with little milk

An hour or so after he ingested 400mg of harmine(isolated from rue)and splashed it down with cup of white coffee....

....20` after he noticed familiar buzz and effects start to develop

....but after another 40 mins he become dizzy and drowsy there was looping in his sight what gave him already mentioned "cybersickness" walking cause vertigo and stuff....

...he decided to purge and did so for 15 mins. he has to lay in to the bed to feel alright and not to be nauseous.

.... this become actually very nice apart ILPT didn`t wanna be incapacitated since he has job to do..

... never mind.... when hi shut his eylids they were geometric swirling patterns, and visuals consistent of faces, machines and others man-made thing well known by ILPT from the real world. Nothing unnatural ...

... those "visions" were strong for about an hour then faded away
....cybersickness lasted another three hours

... need to tell he has also OTC antiallergen medicine CETIRIZINE.HCl one pill of 10mg roughly 4-5 hours beforehand

What caused this nasty side effects of such a beautiful substance???
Tyramine in eggs? cetirizine? or simply OVERDOSE ? Wut?

........it wasn`t tea neither coffee, ILPT used them with sublingual harmine(up to 250mg)with great success

anyway he`s off to bed now as he has 150mg of harmaline sublingually (without any xanthines)and it making him sleepy now Cool



This sounds like a high dose of Caapi (I know you were using harmine). high doses of harmine can cause all the symptoms you mentioned including the stomach issues and visions.

Coffee could have potentiated the all the effects, positive and negative.
The Spice extends life
The Spice expands consciousness
The Spice is vital for space travel
___________________________________________________________________________________________________
Never underestimate the power of STUFF!


I am certifiably insane, as such all posts written by me should be regarded as utter nonsense or attempts to get attention.

I don't know SWIM and personally don't trust him at all. If SWIM is posting, most likely I will not respond...as I said, I don't trust the guy. YOU I trust, but never SWIM.
 
acolon_5
#5 Posted : 5/28/2009 5:36:41 PM

The Great Namah


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Last visit: 17-Sep-2020
Location: The place entites go when they smoke allspice
Dagger wrote:
Quote:
What caused this nasty side effects of such a beautiful substance???

I don't see it as a side effect. I think it is a pretty normal reaction to higher doses of harmine. Perhaps something potentiated the harmine, possibly the coffee.

Btw, did you feel a heavyness? Like a 1000 pound gorilla was sitting on you? Very happy

My guess is that over time, if you worked with the same dosage, the purging will be less likely. Might take some time though.

I welcome the purging, as does many, if not most experienced ayahuasca users.


The purge is very emotinoally cleansing in my opinion. I welcome the purge now, it usually denotes the start of my Ayahuasca experience and helps me enter spirit realm with a clean system. I find that it really releases many negative emotions that I have stored up or have become blocked.


On another note: you'd be suprised at how many Americans have intestinal parasites. I believe a study done about 10 years ago had the number at about 15% (this was done in NY). Undercooked pork and beef were the main culprits, as was drinking unclean water. Caapi is known to help rid the body of parasites, partially due to both purges (top and bottom). I imagine that Harmine would act in a similar way.


The Spice extends life
The Spice expands consciousness
The Spice is vital for space travel
___________________________________________________________________________________________________
Never underestimate the power of STUFF!


I am certifiably insane, as such all posts written by me should be regarded as utter nonsense or attempts to get attention.

I don't know SWIM and personally don't trust him at all. If SWIM is posting, most likely I will not respond...as I said, I don't trust the guy. YOU I trust, but never SWIM.
 
69ron
#6 Posted : 5/28/2009 6:23:09 PM

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High doses of harmine will cause nausea in some people. It's motion sickness style nausea usually, at least for SWIM. Same goes for THH and harmaline.
You may remember me as 69Ron. I was suspended years ago for selling bunk products under false pretenses. I try to sneak back from time to time under different names, but unfortunately, the moderators of the DMT-Nexus are infinitely smarter than I am.

If you see me at the waterpark, please say hello. I'll be the delusional 50 something in the American flag Speedo, oiling up his monster guns while responding to imaginary requests for selfies from invisible teenage girls.
 
kemist
#7 Posted : 5/29/2009 10:32:31 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
Goosh Shocked yesterday was ILPT incapacitated again....

He has only 250mg subling. ... (well some of it dripped with saliva down the throat so it was a bit orally too)
and after an half an hour drank again that bloody coffee in course of 50`

.... he done only 3/4 of mug when need for purge took hold Sad

... it must be something in that bloody coffee what makes him that sicky because this time he didn`t overdosed, did he
... it was nescaffe classic instant coffee Rolling eyes

...the side effects were weaker then those that day before but still noticeable and unpleasant

again when he lay down in bed he felt good again and drifted for couple of hours in "visuals"
...now it`s crystal clear why they initially called it thelepatine
... they`re not real visuals like dmt it`s more like daydreaming. he loves it

.... later when dizzines almost gone he took guarana extract pill and attended his 8 hours shift,
...he has another two coffees after two and four hours since his started mentioned nightshift

There was strange post trip state of mind. ILPT was much clever then usually. His mouth and hand like weren`t quick enough compare to the enormous speed in which he was thinking....
amazing Shocked
... he was also more aggressive Shocked then usual
but this aggression went hand in hand with emphathy, it was like some sort of rightsesous anger
.. only towards people whose deserve it ?.... really interesting
Is here something you didn`t tell me guys???

Anyway he ran out his harmine for a while so now he will test precip. which should be harmaline

after that he will search for actives in salting liquores after precip. and some really gentle purification

anyway he discovered several new things which he would like to share with some "harmala heads" around
as a thanx for initial ideas :idea: he will post(trough me) new thread in extraction`s section
..and since it`s all perfectly legal I probably try do one extraction myself and make some research about therapheutical effects of this compounds Very happy
Thanx very much for your inputs folks, much appreciate.
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
'Coatl
#8 Posted : 5/29/2009 4:55:50 PM

Teotzlcoatl


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I'd leave out the Cetrizine next time.
WARNING: DO NOT INGEST ANY BOTANICAL WHICH YOU HAVE NOT FULLY RESEARCHED AND CORRECTLY IDENTIFIED!!!

I am Teotzlcoatl, older cousin of Quetzalcoatl. My most famous physical incarnation was Nezahualcoyotl, but I have taken many forms since the dawn of the cosmos. In this realm I manifest as multiple entities at a single time. I am many, I am numbered. I am few, but more than one. I am a multifaceted being, a winged serpent with many heads. We are Teotzlcoatl.

"We Are The One's We've Been Waiting For" - Hopi Proverb
 
69ron
#9 Posted : 5/29/2009 7:17:34 PM

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I've got to say that SWIM loves harmine visuals. Harmine is definitely psychedelic for SWIM at 200 mg without any side effects. The visuals are like you said, similar to daydreams. They can be quite amazing. He uses pure harmine he purchases on-line which has all the harmaline removed from it. Harmaline is more likely to cause side effects. You’ll have a better, cleaner experience with pure harmine. With harmaline, side effects kick in at a lower dosage. With THH and harmine, for him, side effects don’t happen until over 300 mg are taken. With harmaline, side effects happen at about 150 mg.

If you really want a full psychedelic experience from harmala alkaloids, the best combination is harmine + THH, about 50:50. THH is more of a true psychedelic than harmine, while harmine is more visual than THH. When the two are combined, the experience is quite something.

SWIM is thinking about mixing harmine with 1-3 Datura stramonium seeds or perhaps 1-3 Datura inoxia seeds in order to take a larger dose without the nausea. He’s nervous about it though and has yet to get the guts to try it out.

SWIM experienced full psychedelic style effects from THH, without the strong visuals of harmine, at 350 mg orally. The problem was dizziness and nausea was present at that dose which made the experience unpleasant. At 300 mg THH didn’t cause psychedelic effects, but there were also no side effects, just euphoria, tingling sensations, etc. At 350 mg, effects included clear alteration of sounds, mild visuals, emotional and mental psychedelic effects similar to LSD, stimulation, feeling of movement without actually moving, slight slowing of time, it was sort of like taking LSD, but along with those effect were nausea and dizziness.

I’m thinking since there was nausea and dizziness, that most likely 1-3 Datura inoxia seeds would be effective at blocking the side effects. Nausea and dizziness are symptoms of motion sickness and Datura inoxia seeds contain nearly pure scopolamine which is the number 1 medication used to treat motion sickness. Even NASA uses scopolamine. Datura stramonium is also useful for treating nausea, but not motion sickness style nausea. So I’m thinking Datura inoxia would be best.

At some point SWIM will try it out and post a report.

Can you imagine s strong harmine trip without the side effects? That would be quite awesome. I’m pretty sure either 1-3 seeds of Datura inoxia or Datura stramonium will make that possible. Hopefully Datura stramonium works because it potentiates the effects of other psychedelics and will probably make the harmine active at even lower doses.

SWIM is excited to try this, but still a little nervous about it.
You may remember me as 69Ron. I was suspended years ago for selling bunk products under false pretenses. I try to sneak back from time to time under different names, but unfortunately, the moderators of the DMT-Nexus are infinitely smarter than I am.

If you see me at the waterpark, please say hello. I'll be the delusional 50 something in the American flag Speedo, oiling up his monster guns while responding to imaginary requests for selfies from invisible teenage girls.
 
kemist
#10 Posted : 5/30/2009 9:05:35 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
Dagger wrote:

250 mg sublingually? I thought these maois were about 10x as potent sublingually compared to orally. No wonder you get these effects! Laughing

10x Shocked Blimey!!! he knew is shorter and stronger subl. but 10x ? Shocked

Dagger wrote:

I don't think it is the coffee that makes you feel bad. The thing about these maois is that it usually takes something like 1 hour+ before crap comes up, and that is when you start feeling bad. You can get strong effects earlier too, but it takes a little time to digg up stuff.

never say never for instance coffee contains traces of toxic acrylamide:
Andrzejewski wrote:

The levels of acrylamide ranged from 45 to 374 ng/g in unbrewed coffee grounds, from 172 to 539 ng/g in instant coffee crystals, and from 6 to 16 ng/mL in brewed coffee.
could be any other shit in there you never know
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
kemist
#11 Posted : 5/30/2009 9:17:32 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
69ron wrote:
He uses pure harmine he purchases on-line which has all the harmaline removed from it. Harmaline is more likely to cause side effects. You’ll have a better, cleaner experience with pure harmine. With harmaline, side effects kick in at a lower dosage. With THH and harmine, for him, side effects don’t happen until over 300 mg are taken. With harmaline, side effects happen at about 150 mg.
Well in europe there isn`t harmine vendor even that THH one didn`t pop out yet Crying or very sad
ILPT admitting there could be up to 10-15 % of harmaline in his "harmine".
However new approach was determined and will be proceed to obtain virtually harmaline-less harmine
69ron wrote:

If you really want a full psychedelic experience from harmala alkaloids, the best combination is harmine + THH, about 50:50. THH is more of a true psychedelic than harmine, while harmine is more visual than THH. When the two are combined, the experience is quite something.

pheeww sounds good but again we not in USA and parrot cannot fly that far to get some Crying or very sad
69ron wrote:

SWIM is thinking about mixing harmine with 1-3 Datura stramonium seeds or perhaps 1-3 Datura inoxia seeds in order to take a larger dose without the nausea. He’s nervous about it though and has yet to get the guts to try it out.
I’m thinking since there was nausea and dizziness, that most likely 1-3 Datura inoxia seeds would be effective at blocking the side effects. Nausea and dizziness are symptoms of motion sickness and Datura inoxia seeds contain nearly pure scopolamine which is the number 1 medication used to treat motion sickness. Even NASA uses scopolamine. Datura stramonium is also useful for treating nausea, but not motion sickness style nausea. So I’m thinking Datura inoxia would be best.

ILPT decided to try hyosc. niger seeds but dose is not yet determined
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
kemist
#12 Posted : 5/30/2009 9:19:28 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
Dagger wrote:
Well, maoi can make you feel REALLY bad, especially on high doses, so that would be my main suspect. All your symptoms are common on higher doses of caapi.

Yep there wasn`t mentioned one thing. His scales are not calibrated and very accurate. What if 350mg was actually 450mg Shocked
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
SWIMfriend
#13 Posted : 5/31/2009 2:22:24 AM

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kemist wrote:
Dagger wrote:
Well, maoi can make you feel REALLY bad, especially on high doses, so that would be my main suspect. All your symptoms are common on higher doses of caapi.

Yep there wasn`t mentioned one thing. His scales are not calibrated and very accurate. What if 350mg was actually 450mg Shocked


The effective dose vs LD50 ratio is an important consideration for drug safety...
 
69ron
#14 Posted : 5/31/2009 5:28:58 AM

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There are many cases of people being poisoned from taking extreme overdoses of peganum harmala, however no human deaths have been reported. The toxic symptoms usually subside within 12 hours. People have eaten up to 100 grams of seeds and survived. That’s a LOT of harmine. With an average of about 3% harmine/harmaline, that’s 3000 mg of harmine/harmaline.

I wouldn’t worry too much about fatal poisoning from harmine/harmaline.

I've included a paper with a case study on the toxicity of peganum harmala.

You may remember me as 69Ron. I was suspended years ago for selling bunk products under false pretenses. I try to sneak back from time to time under different names, but unfortunately, the moderators of the DMT-Nexus are infinitely smarter than I am.

If you see me at the waterpark, please say hello. I'll be the delusional 50 something in the American flag Speedo, oiling up his monster guns while responding to imaginary requests for selfies from invisible teenage girls.
 
69ron
#15 Posted : 5/31/2009 5:33:01 AM

DMT-Nexus member


Posts: 5826
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The attachment is not workingSad

Can't I add a PDF? I believe it worked before.
You may remember me as 69Ron. I was suspended years ago for selling bunk products under false pretenses. I try to sneak back from time to time under different names, but unfortunately, the moderators of the DMT-Nexus are infinitely smarter than I am.

If you see me at the waterpark, please say hello. I'll be the delusional 50 something in the American flag Speedo, oiling up his monster guns while responding to imaginary requests for selfies from invisible teenage girls.
 
kemist
#16 Posted : 5/31/2009 8:48:50 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
THERE WASN`T PROBLEM WITH SCALES

They are been calibrated yesterday and are accurate as before. the have +/- accuracy 2 mg so there wasn`t that big different, sorry about that

..... Anyway I absolutely forgot that ILPT has had higher dose of mentioned harmine probbably week before. It was round 250 mg but that time he hasn`t had any coffee....
For some reason he hasn`t eat anything apart some fruit and veg that day and ate vegetarian meals two days beforhand..... and he didn`t puke that time....

Seems like more toxic shit you have in your body less harmalas is required for purge...

As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
kemist
#17 Posted : 5/31/2009 9:19:19 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
Dagger wrote:

Indeed, that is my experience too. I feel that there are different levels of "toxic shit". You have the surface level that triggers very easily and that can quickly be discarded. Then again, many other herbs triggers this level too. The more caapi/maoi you take the deeper it digs. Some shit takes a long time to surface. There may be other stuff that has to be dug out to get to it. You can use very strong doses of maoi if you want to dig new stuff out. Adding DMT also helps. It puts more force and energy behind the caapi.

Also intention seems to have something to do with it. You can work for years without getting any significant purging, then you change your intention on what you want to work with, and then suddenly it comes. An intention of healing your body and mind may make you purge more than an intention of exploring hyperspace.


GOOSH If one never tried harmalas ,he would say what you wrote is INSANE, but it`s actually NOT
...


As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
kemist
#18 Posted : 5/31/2009 9:27:42 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
Hehe Laughing ILPT will purge with pride, from now on, lol Laughing
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
kemist
#19 Posted : 5/31/2009 9:49:56 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
Anyway now Harmaline is tested...

....Ilpt decieded that most reliable would be using it half subling(to get the buzz quicker Smile )and half oraly(to make it last).This way they dissolving in matter of 5-10 mins under the tongue and dripping with saliva down the throat. Overall after ~ 15 mins bitterness becomes annoying so he splashing it down with some water.
He found out that the bitterness of alks have some insides. But he generally like bitter stuff(he doesn`t even use sugar for tea or coffee)and he eating sweets only when stoned get `munchies`

...anyway

1,50 mg day before yesterday didn`t brought any effects but significant mood improvement for 6-8
hours plus some decent yawning (which was killed with two coffees and a bull)

2, 80 mg yesterday brought on greater mood ,but there were tiny signs of looping and slight(yet comfortable) dizziness crept in...

So far no vision ......

....100mg should bring more dizzines and ILPT has job to do therefore testing have to continue on Tuesday...

For now it seems that harmaline is more sleepy and lazy then harmine...


what light should ILPT take with his harmalas after he establish adequate dose for him ...

he has about 20mg of vicoius Jungle spice, but he would like something more healing full...
...should he grab some plant(psychotria)
What ayahuascero recommended
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
kemist
#20 Posted : 5/31/2009 10:48:29 AM

John


Posts: 700
Joined: 31-Aug-2008
Last visit: 27-Jan-2024
Location: Highland
Dagger wrote:
Here is a recent thread about caapi and its effect from the ayahuasca forum:
Effect of high vine low admix vs low vine high admixture...


Rolling eyes Rolling eyes Rolling eyes Rolling eyes Rolling eyes NOT REGISTERED Rolling eyes Rolling eyes Rolling eyes Rolling eyes Rolling eyes Rolling eyes

can ya copy-paste higlights please ?
As a kemist I never met ILPT in physical form and never talk to him. He share his wisdom, trough my mind, telepathicly only. Please don`t prosecute me, for his possible illegal activities. He is bonkers about chemistry and doesn`t even exist in this primitive reality !!!
 
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