I recently met someone who frequently does ayahuasca. She told me about these mushrooms that her shaman grows in Peru... All I know is that they are some kind of Psilocybin mushrooms (not sure which strain) that are "watered" with ayahuasca brew while they are growing. I'm not sure what the aya brew consisted of either. Then, a few days before harvesting the mushrooms, they're drenched with aya brew.

She says 1 cap is MORE than enough for an extremely strong trip. She doesn't like to hand them out because she claims they are too potent. Maybe after we do aya next month she'll give me one to try.

I couldn't get much more info out of her. Has anyone every heard of a recipe like this before? I've heard of taking harmalas during or before a shroom trip but never heard of this before. Anyone?

Sounds like a nice urban legend.

By what metabolic pathway would the mycelium/mushrooms make use of ayahuasca hydration?

i wouldn't take it too seriously.
at most it may potentiate a placebo effect. there is of course a strong interaction between the two substances when dosed together but that alkaloid absorption by the mushrooms won't happen.

i' wouldn't take it seriously either. the mushrooms produce much of their own DMT, and it the conversion is rapid/spontaneous. adding dmt is a good way to stall growth, NMT is a more suitable precursor.

Sounds like a tall tale to me, I've heard it said many times that feeding mycelium DMT will produce more potent fruits, but no actual data on it or explanation of how it might work.

Because there is no data or explanation, does that mean it "can't" work? I understand what everyone is saying (how it doesn't make any botanical sense). But has anyone actually tried it first hand?

Also, I was thinking maybe the affect came from soaking the mushrooms with harmalas right before harvesting. Maybe they evaporate onto the mushroom instead of grown into it?

Great, another deliberate rigged misquote.

You quoted me once then quoted a quote that isn't even in the quote you quoted....

Where did I say ' ''can't'' work ' ?

I don't think people are willing to waste ayahuasca on this, and everyone who seems to know something about plants and chemistry don't see why they should when it makes no sense.

Still, once again, I'm definitely not saying it can't happen at all.

Why not try it yourself and get back to us with your results ?

Oh sorry I didn't mean to imply that you said it can't work. Ignore the quotes I added those for emphasis, not for quoting purposes. I guess I should have italicized it.

Either way, I guess I'll find out soon if it's for real and report back.

I suppose theoretically if you were to dry the mushrooms and rehydrate them in huasca, the aya infused mushrooms could be pretty neat. That's the only thing I can think of that would feasibly make this work.

Ah no worries tonyx3 I look forward to it

Dreamer, did you just invent mushroom changa ?

Well,

benzyme once told me you could add tryptamine to p.cubensis mycelium substrate to increase psilocybin concentration. (i think)


I may not have remembered that convo correctly. It's not exactly aya, but it could be, in effect, the same thing that's working.

tryptamine, yes. harmala alks, no. the enzymes involved with psilocin/psilocybin production will not use those.

Am i the only one completly ignoring the physical side of molecules, chemicals and stuff, while seeing a strong potential for energetic, vibratory (spiritually) exchange of informations between 2 very powerful "magic" entities?

Come on guys use both of your brain hemispheres...!
Lets create knowledge/wisdom through experience, we can argue about facts later...

@tonyx3
Try it out after you had Ayahuasca, and when you are on it, ask Aya and the shrooms directly about it.

Have a joyful and save journey!

nothing new, people have done aya with mushrooms before. the title says grown with ayahuasca.

Not quite, I actually invented that some time ago when I made my changa using mushroom tincture to dissolve the dmt and infused that into the plant matter

I never tried this experiment.

BUT the talk seems to be about precursors enhancing production.

Isn't it relevant that mushrooms are like 90% water and grow rapidly, so that any water is quickly absorbed and stored within its cells? It seems to me that physically if the solution is viscous enough the desired alkaloids would be retained in the dried mushrooms. Through wicking and simple mechanical action. As long as the additional substances didn't kill the mushrooms.

I know the nature of fungus is to clean and restore the natural world to a purer state, and that the water released by them is cleaner than it was, but wouldn't that entail that if the water is contaminated by anything then it would be trapped in the mushrooms' fruit which returns to the soil?

A mushroom is essentially a physical wick, like other plants.

Shoot, people color their carnations with food coloring and nobody has to think about how Yellow#3 and Red#6 induces the production of orange in a carnation.

I sort of thought that was why mushrooms have been most recently looked at as a novel way to remove heavy metal toxins, industrial waste and even radiation from contaminated areas. The mushrooms absorb all that and are taken away. Mushrooms with enough radiation to trip a geiger counter, or enough pesticides absorbed to really harm you. I find it hard to believe that the fruiting bodies would accept all kinds of toxins but not some simple plant alkaloids?

IDK really but i could see it absolutely working. What am I missing?

nothing about mushrooms absorbing harmala alkaloids, but metabolyzing them isn't likely. enzymes are largely substrate-specific.
you can't just throw in random compounds and realistically expect the mushroom to transform it into other different compounds. apparently, they are encoded to metabolize simple tryptamines.

i'd try it though, adding harmalas to the substrate prior to PC'ing. who knows, maybe the fruits would fluoresce under the blacklight, then you'd know it worked; run a control group with no harmalas added.

well i'd say that at most the mycelium would digest the harmalas for the sake of it's own growth and nothing more, like it was any other kind of substrate e.g. rye, coir or whatever you choose.
i've even seen people grow cubensis from cigarette buds

it would be a cool experiment, and by all means do it if you've got the opportunity, but i really don't think the mushroom would get any other compounds going besides it's basic psychoactive ones.

OH yeh word I missed the part where anyone said they metabolized into anything else.

SHe made mushrooms jacked up with harmalas and DMT, like if you simply ate psilocybin and ingested pharma at the same time, you'd potentiate the psilocybin with the harmalas and also be influenced by DMT.

There's no reason to do this experiment except for the novelty.

You could make a pharmahuasca solution and soak dried mushrooms in it, or inject them with a syringe.

Lacing drugs with other drugs is risky business if one wants precise dosing and safety and such. We want that here, do we not?

See, I never inferred that anything was metabolized into anything else. I will now go read it over and see where that was suggested.

My bad if I jumped the gun.

One could take said mushrooms and inject them with 4-HO-DMT as well to make them super strong, or hope a solution was absorbed mechanically during growth... it's pointless.

True that, nothing about the internal chemistry changes. Feeding them a precursor to promote production of desired goodies is a whole different topic. I have a strong feeling it wasn't this topic and was mistakenly inferred.

I'll reread it, I'm admittedly somewhat distractable at the moment.