If you mix ethanol with water 1 part to 1 part and heat it which will evaporate first the ethanol?

Both, if you heat it to boiling an azeotrope will form. It will be comprised of 95% ethanol and 5% water, and will boil at 78°C. This will continue until the Ethanol has been exhausted.

If you maintain a temp below 78°C Sister would expect their rate of evaporation to be more even, but cannot say for certain the exact ratios.

thx sister


what if you mixed petroleum ether and ethanol and boiled

You asked a similar question here. Is there a reason you keep asking this?

in that question I said separate like waiting for two layers to form and then using a separator funnel to get one layer. So when I heard him use the word azeotrope (which im a newbee to this) I was woundering if I had alittle ether in alot of ethanol if I need to do was just heat it allittle and all of the ether would come off first with just loseing alittle of the ethanol.

I think this answer is a bit confusing, if not misleading...the azeotrope will form in the vapors (whether it is collected or not) produced by the boiling.

to answer the OP: yes, if you have a mixture of water and ethanol and boil this up, the ethanol will evaporate first leaving behind water. While the ethanol evaporates, you will also evaporate a quantity of water.

Your questions are still about separating Petroleum ether and Ethanol.
My question is still why?
Am I missing something?
At what point in your extractions are these two solvents coming together?

To answer your question, the temperature the Petroleum ether would come off at would depend on its composition. It is a mixture of hydrocarbons so a range of temperatures would be needed. Some of the hydrocarbons can have Boiling points very close to Ethanol so a properly run distillation column would be needed. At the take off point the temperature would need be 78.4 like dr_sister as already stated to remove the ethanol. This temperature is also dependent on atmospheric pressure.

The idea is to make rue into a tincture by taking 100 grams of grinded seeds and soaking them in ethanol on a hot plate on low and blending them with a blender stir stick now and then, waiting 3 days with 8oz of ethanol until the ethanol was black and you could not see through it with a light. Then add 8oz of fresh ethanol and did 3 pulls this way. Problem is that after 3 8 oz pulls it looks like the seeds could still yield more.
Now I have 24 ozs of tincture but rue seems kinda dirty and taste real bad so I'd like to mix it 1:1 with something maybe petroleum ether to see if I can get some of the crap out of it then separate the ether layer and heat the tincture to remove any left over ether in the tincture so its safe to serve up.


How do I know when my seeds are done yeilding. shouldnt I be able to put fresh ethanol on them and after blending and heating them in ethanol for 3 days there should be no color change to the ethanol?

Is there something else I could use besides ether thats more natural and non toxic or easly removeable that would clean the tincture up to get ride of what ever is in there that taste so bad and have a purer harmala or harmaline tincutre?

I'd recommend skipping alcohol altogether and just doing A/B water extractions. If you have a pressure cooker, you can even skip the acid. It's infinitely more efficient than any alcohol extraction I've tried or seen posted. You will be pulling from those seeds forever with alcohol, imo.

Pet ether won't do anything to clean up the extract...nor will DCM, D-Limonene, Xylene, Toluene, Naphtha, or a host of others, afaik.

+1

Have either of you too ever tried it and are speaking from experience?
Do you really believe that there is nothing out there that is not soluable in ethonal that will not pull out things that are?

I'm speaking from experience.

5 years ago I tried whiterasta's method and similar ethanol extractions of rue seeds. I acquired a usable product that was of significantly lower yield and purity to what I now extract regularly from rue seeds, using water, vinegar, lye, and a pressure cooker.



I'm not sure I fully understand the question.

Jorkest found, after much experimentation, that the ideal proof for etoh is 120...or 60% etoh. The reason being that harmala alkaloids are incredibly water soluble and 60% etoh pulls significantly more alkaloids than higher proofs. Water pulls more alkaloids than ethanol, ime. Harmala alkaloids are so soluble in water that there is an assumed yield loss even when basing to an extremely high pH.

So, ime and imo, you can't beat water for harmala extractions. Try it and see for yourself

Boil of the ethanol dissolve the powder in water filter and then freebase or salt out the alks. This should clean it up I would have thought. If you are concerned about leaving anything behind in the seeds just boil them up and do a little a/b