I am literally ecstatic to try DMT for the first time. If my friend comes through, I should have some tomorrow. I'm supposed to try it with a few other friends. I bought a VaporGenie Sherlock and a torch lighter so I'm all ready.

One of my friends is having surgery the very next day. So he was wondering if the DMT will show up in his blood work at all and if it is safe to try a day before surgery? Any input on this would be highly appreciated.

Assuming this is a sincere question, would you really want to have this experience the day before surgery? Not something to be cavalier about - both this drug and surgery.

Physiologically - depends on type of surgery, anesthesia involved, etc. doctors aren't cops and generally don't care what's in yr blood work, even though tryptamines wouldn't show up.

I don't know you, and am not inclined to judge, however your question comes across to me anyway as lacking a sense of how serious this compound can be.

Be safe

Why not suggest you both wait until after surgery?
There is no way to know whether it could cause complications and the operation would surely be on his mind DMT is definitely most enjoyed with total respect and no immediate concerns on the mind. Set and setting are important the DMT experience can be a very intense experience.

Given the countless trip reports regarding the importance of set i am with Amygdala on this one. DMT has an amazing ability to take what is in your head and use it in very interesting ways.
I have a needle phobia so the the thought of a DMT experience with surgery on my mind is..well, unthinkable. To be honest i will not be able to journey for quite a while now after just writing about it!

Good luck to your friend in their surgery.

what a question..
OF course you should wait until you fully recovered from this medical thing.

Alright, thanks for all the replies. I'll tell him that he should probably wait off on trying it out then.

I don't see how it could possibly show up on blood work or cause any complications with the surgery itself....but just the thought of having to get surgery the next day during a DMT trip (his first, no less) is something I would definitely avoid

Worth mentioning here perhaps re: changa or ayahuasca - dangerous interactions between MAOI's or RIMAs and general anesthesia.

There is unfortunately not a plethora of studies on this, but here is a peer reviewed journal article on this topic for those interested:

http://ceaccp.oxfordjour...rg/content/10/6/177.full

RIMA's are perhaps less of a concern than orally ingested MAOI's, but I personally wouldn't risk either. I'll follow this with an excerpt of this article - the translation basically suggesting that the combination could precipitate a hypertensive crisis - particularly if the anesthetist or anesthesiologist is unaware that MAOI's are present in the system and the use of pressor agents to manage blood pressure could be catastrophic.

An excerpt:

The most important anaesthetic consideration for patients taking MAOIs relate to the profound pressor effect that may be seen after administration of both indirectly and directly acting sympathomimetics. The metabolism of indirectly acting sympathomimetics is inhibited, resulting in the potentiation of their action. Where absolutely necessary, direct sympathomimetics are preferable (by virtue of the fact that they are also metabolized by catechol-O-methyl-transferase so are not as dependent on MAO), but still require caution because there remains the risk of hypertensive crisis.

Meperidine can precipitate a serotonergic crisis in patients taking MAOI as it too interrupts presynaptic uptake of serotonin. It should therefore be avoided in patients known to be on an MAOI.

In the elective setting, there is some debate regarding the management of patients on MAOI. Although the risks associated with anaesthesia in those taking this group of drugs are significant, abrupt withdrawal may precipitate serious psychiatric relapse. Traditionally, irreversible MAOIs have been stopped 2 weeks before operation; however, omitting the dose of moclobemide on the day of surgery is acceptable. It has been suggested that in the elective situation, patients could be switched from an irreversible MAOI to moclobemide to avoid a prolonged period of discontinuation.2

When there is no time to consider withdrawal of MAOI, the anaesthetist must avoid meperidine and use only direct-acting sympathomimetics with extreme caution.