I've seen a few episodes before when my relatives turn it on and there does seem to be quite a bit of references to hallucinogenic drugs in the show (i haven't seen the one you're talking about but there are others with subtle references to them as well). So, one day i also decided to look it up and it turns out the guy who created the show is J. G. Quintel, and Regular Show itself actually came from a short he made a few years back called "2 in the AM PM", which shows pre-Mordecai and Benson on an acid trip while on the job.
http://m.youtube.com/wat...Fwatch%3Fv%3Dy894QNtX0VAI found it rather interesting considering the show comes on during the daytime on a channel with kid shows.
"If the words ‘life, liberty, and the pursuit of happiness’ don’t include the right to experiment with your own
consciousness, then the Declaration of Independence isn’t worth the hemp it was written on.”
-Terence McKenna