DMT-Nexus member
Posts: 64 Joined: 25-Aug-2012 Last visit: 08-Feb-2015 Location: canada
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does anyone know how long someone has to be off oxycotin before they can do ayahuasca, i know with anti depressants its 3 weeks but its not that long for oxys i believe or is it any help would be apperciated
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DMT-Nexus member
Posts: 699 Joined: 06-Jul-2012 Last visit: 20-Dec-2018
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I wasn't aware there was any contraindication. I read your title and thought you combined oxytocin(not oxycodone/contin) and aya. I was intrigued. "I am cursed by the blossoming knowledge of my feminine ideal and she looks suspiciously like you."
"Everybody is a genius. But if you judge a fish by its ability to climb a tree, it will live its whole life believing that it is stupid." -AE
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jai
Posts: 767 Joined: 12-Feb-2013 Last visit: 06-Nov-2023
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Du57mi73 wrote: I read your title and thought you combined oxytocin(not oxycodone/contin) and aya. I was intrigued.
I did the same thing,
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DMT-Nexus member
Posts: 1116 Joined: 11-Sep-2011 Last visit: 09-Aug-2020
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anabolic_hippie wrote:does anyone know how long someone has to be off oxycotin before they can do ayahuasca, i know with anti depressants its 3 weeks but its not that long for oxys i believe or is it any help would be apperciated It's oxyco ntin, not oxycotin. Might help with your searches. Good luck!
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xͭ͆͝͏̮͔̜t̟̬̦̣̟͉͈̞̝ͣͫ͞,̡̼̭̘̙̜ͧ̆̀̔ͮ́ͯͯt̢̘̬͓͕̬́ͪ̽́s̢̜̠̬̘͖̠͕ͫ͗̾͋͒̃͛̚͞ͅ
Posts: 1716 Joined: 23-Apr-2012 Last visit: 23-Jan-2017
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http://app.purduepharma....i.aspx?id=o#section-15.3Quote: The activity of OxyContin is primarily due to the parent drug oxycodone. OxyContin is designed to provide delivery of oxycodone over 12 hours. [..]
Oxycodone is extensively metabolized and eliminated primarily in the urine as both conjugated and unconjugated metabolites. The apparent elimination half-life ( t½ ) of oxycodone following the administration of OxyContin was 4.5 hours compared to 3.2 hours for immediate-release oxycodone.
https://en.wikipedia.org...ki/Elimination_half-lifeRead and learn
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DMT-Nexus member
Posts: 64 Joined: 25-Aug-2012 Last visit: 08-Feb-2015 Location: canada
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so does anyone know the answer without me having to become an expert on half lifes of certian drugs then reserching weather or not those half live interact with maois.
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xͭ͆͝͏̮͔̜t̟̬̦̣̟͉͈̞̝ͣͫ͞,̡̼̭̘̙̜ͧ̆̀̔ͮ́ͯͯt̢̘̬͓͕̬́ͪ̽́s̢̜̠̬̘͖̠͕ͫ͗̾͋͒̃͛̚͞ͅ
Posts: 1716 Joined: 23-Apr-2012 Last visit: 23-Jan-2017
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Yeah math - not even once!
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DMT-Nexus member
Posts: 64 Joined: 25-Aug-2012 Last visit: 08-Feb-2015 Location: canada
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sorry i dont understand your reply yeah math - not even once
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DMT-Nexus member
Posts: 14191 Joined: 19-Feb-2008 Last visit: 28-Nov-2024 Location: Jungle
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Wait at least 5x the half-life. For some substances like SSRIs that are taken regularly, better wait even more, as you said. But dont interupt your treatment without consulting your doctor.
Why are you talking oxycontin? How regularly are you taking it?
I`d shoot a pm to corpus callosum just in case anyways, he`s the most qualified person to answer this to you.
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DMT-Nexus member
Posts: 64 Joined: 25-Aug-2012 Last visit: 08-Feb-2015 Location: canada
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i have never taken it i know a friend who is hooked on oxy and wants off, i told him that the aya brew could help him hes very interested.
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xͭ͆͝͏̮͔̜t̟̬̦̣̟͉͈̞̝ͣͫ͞,̡̼̭̘̙̜ͧ̆̀̔ͮ́ͯͯt̢̘̬͓͕̬́ͪ̽́s̢̜̠̬̘͖̠͕ͫ͗̾͋͒̃͛̚͞ͅ
Posts: 1716 Joined: 23-Apr-2012 Last visit: 23-Jan-2017
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anabolic_hippie wrote:sorry i dont understand your reply yeah math - not even once Sorry pal, I thought you would take the time to at least read and think about the three sentences: Quote: The activity of OxyContin is primarily due to the parent drug oxycodone. OxyContin is designed to provide delivery of oxycodone over 12 hours. [..]
Oxycodone is extensively metabolized and eliminated primarily in the urine as both conjugated and unconjugated metabolites. The apparent elimination half-life ( t½ ) of oxycodone following the administration of OxyContin was 4.5 hours compared to 3.2 hours for immediate-release oxycodone.
The biological half-life or elimination half-life of a substance is the time it takes for a substance (for example a metabolite, drug, signalling molecule, radioactive nuclide, or other substance) to lose half of its pharmacologic, physiologic, or radiologic activity, as per the MeSH definition.
No need to become an expert, these 3 sentences and some fraction math is all you need to answer the question for yourself. After some iterations, the system has cleared the drug. For Oxycodone you need 4.5h iterations. Btw, for every prescription drug you'll find prescribing information. So google PRESCRIBING INFORMATION oxycodone and you'll find: http://labeling.pfizer.c...showlabeling.aspx?id=620Quote:7.4 Monoamine Oxidase Inhibitors (MAOIs) Monoamine oxidase inhibitors have been reported to intensify the effects of at least one opioid drug causing anxiety, confusion, and significant depression of respiration or coma. The use of OXECTA is not recommended for patients taking MAOIs or within 14 days of stopping such treatment. So drinking Aya while high on Oxycodone is a no-no. Let the drug reach its pharmacologic activity of ~ 2-0,X % and then think about drinking Aya.
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DMT-Nexus member
Posts: 49 Joined: 09-Dec-2013 Last visit: 31-Jan-2014
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I agree with the good advice given above. Mixing ayahuasca and opiates is dangerous. It would be foolhardy to play doctor and/or shaman in this situation.
If your friend is hooked on pain pills, you should encourage them to go to rehab and be in the care of experts, medical experts! After that process, if existential questions still remain, then maybe ayahuasca is a good idea. But only after. More drugs do not, and cannot, cure drug addictions.
Also, having had multiple friends lose themselves in the world of addiction, it is always better to express your concern and support for their wellness sooner than later. The longer we wait, the worse these situations can get!
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Homo discens
Posts: 1827 Joined: 02-Aug-2012 Last visit: 07-Aug-2020
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SkyKitty wrote:I agree with the good advice given above. Mixing ayahuasca and opiates is dangerous. It would be foolhardy to play doctor and/or shaman in this situation.
If your friend is hooked on pain pills, you should encourage them to go to rehab and be in the care of experts, medical experts! After that process, if existential questions still remain, then maybe ayahuasca is a good idea. But only after. More drugs do not, and cannot, cure drug addictions.
Also, having had multiple friends lose themselves in the world of addiction, it is always better to express your concern and support for their wellness sooner than later. The longer we wait, the worse these situations can get! I completely agree with this, even as a person who has found psychedelics to be an integral part of their recovery. He'd be more likely to benefit from the ayahuasca if he has already kicked the habit first. That being said, to answer your question, I would advise he be off the opioids for 2 weeks prior to ingesting any MAOI's. Opioids are mostly out of the system in a week, give or take a few days due to personal metabolism. when I was using, I failed drug tests after 6 days of abstinence, and passed drug tests after 7 days of abstinence. Drug tests have cutoff levels though, so a person can have a certain amount of the drug remaining in their system and still pass. It is safest to be absolutely certain that there are no traces of oxycodone in his body whatsoever before taking ayahuasca. And, as stated above, corpus callosum is definitely the guy to ask about these things.
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gufyg
Posts: 711 Joined: 03-Jan-2010 Last visit: 08-Jul-2017 Location: Roving North America
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Well I was hooked on kratom for two years, hydrocodone for another one, and as long as I was using kratom I still used harmala/ayahuasca - HOWEVER, others have taken this mix and gotten very sick with headaches and nausea. Kratom has lots of secondary alkaloids with various effects, so it isn't a good comparison with oxycodone. Hydrocodone, on the other hand, is in the same ballpark (not to conflate the two, as oxycodone is much stronger). However, my soul was being completely dampened by the stuff and, with all the anxiety from a pending spine surgery, depression, interpersonal strife, and whatnot - I didn't do much tripping during that year. I tried to keep to dose very low (5-10mg) when I did, as opposed to my normal dose of 30-60mg daily, and tried to not take my nighttime dose after the trip had ended. But withdrawing from opioids is very painful and WILL influence trips negatively. I think it takes a person very skilled and experienced with psychedelics to use them DURING an opioid withdrawal. And it is potentially quite dangerous, psychologically and physically. I would recommend getting the W/D's over with before tripping. However, it IS very useful to see what how dumb addiction is, and Ayahuasca or Harmala/Jurema seem to be keen on telling addicts what's up. بسم الله الرحمن الرحيم
Fairly responsible Kratom user.
"whenever he drank ayahuasca, he had such beautiful visions that he used to put his hands over his eyes for fear somebody might steal them." in between the grinding-brakes of a train crash while aluminum-foil robots make obnoxious sex noises on a static-filled walkie-talkie radio.
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DMT-Nexus member
Posts: 49 Joined: 09-Dec-2013 Last visit: 31-Jan-2014
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SkyKitty wrote:But only after. Sorry, I didnt mean to be absolutist about it, just cautious!
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