I gave a portion of my recently extracted product to a friend. I had tried it previously and it worked out very well for me. she, on the other hand, said she felt almost no effects, or barely anything. we both used the same machine, and she seemed to inhale more than i ever have.
she is on prescribed Subutex to treat an opiate addiction, and Viibryd, which is the SSRI.
and yes, i know there can be drastic consequences for someone with mental health and other drug issues using powerful psychedelics, so before i get a lecture on that i made sure she understood what could happen as a result of DMT usage before hand.