Hi everyone.
I am on a bad start of my first extraction but doing some research and hoping for the best. DMT is something that I know I have to try after having researched it, just should have researched the extraction more before starting.

From my research I am not afraid of trying DMT at least once, but I was wondering, does anybody know if long term use of the molecule recreationally affects the way or the amount that the brain makes it naturally? If so, how much usage is recommended?

I know these things vary due to individual differences, but I was just wondering if anyone knew of any research regarding this or can speak from personal(or personalish) experience.

Thank you.

it is not even known that the brain creates DMT, so we cannot know how it would affect the creation of it.

but i believe DMT promotes synaptic neuroplasticity, making your receptors more receptive (...for lack of a better word) to agonization.

That is new to me, I thought that DMT was produced in the pineal gland. Do you have any links from which I could learn more?

Thank you.

From everything that I have ever come across (all external knowledge) from the medical field and otherwise, DMT is indeed produced in the pineal gland naturally, but is only excreted twice in your life, once during birth, and the other time during death. I also suspect that one can access natural release through meditation, but this is pure speculation with no medical backing to my knowledge (or maybe there are medical studies that I'm not aware of, dunno)

Hope that helps

The Pineal-produced DMT, as well as the birth/death release of DMT we're only theories by Rick Strassman. They've been spread around as being fact, though they have yet to be scientifically proven. His theories MIGHT be true, but we don't know for sure.

We know for a fact that DMT is produced by the mammalian body, and that it has been found in trace amounts in various places of our anatomy (the pineal being one of these), but we just don't know where or how exactly it's produced.

I see, thanks for clearing that up. I took it as common knowledge since there were tons of documentaries even on the History channel on the "Soul Molecule" and this same stuff was repeated over and over, and of course in many other sources... but the information is always the same and is consistent with what you're saying.

In any case I was able to dig up these links for the OP, hope they help, just regurgitating the same news tho;
http://wideshut.co.uk/dimethyltryptamine-dmt/

And a PubMed study that I can't seem to get to load for me
http://www.ncbi.nlm.nih.gov/pubmed/4987

...Links? Where did you get this information?

read this thread https://www.dmt-nexus.me...aspx?g=posts&t=49070

Here's a study that confirms natural (endogenous) DMT is present in human cerebrospinal fluid
http://bjp.rcpsych.org/content/132/2/139.short
and abstract for that study;
http://anp.sagepub.com/c...ntent/abstract/12/4/221