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Entheologist
#1 Posted : 6/14/2013 2:15:28 AM
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Hi, I'm a chemistry and pharmacology student with a profound passion for the exploration of consciousness and reality. I don't know what to write for an essay, so I will post something I wrote recently, something which I want to share with others but have not posted anywhere yet. Its about some connections I've stumbled upon over the years involving Amazonian shamansim, pharmacology, spirituality and the limitations of the western paradigm. Here it is:
I read an article about the use of Cats Claw by indigenous people in the Amazon jungle. Pharmaceutical companies are researching Cats Claw extensively due to its wide range of medicinal properties. I can't find the original article I read, but heres an excerpt from a thread:
http://vitanetonline.com/forums/1/Thread/666
the explains the points of interest:
Quote:
To determine which cat’s claw roots do have healing properties, we have to go to the rainforests of Peru. This is where Uncaria tomentosa thrives. It’s a woody vine that’s found at the base of tall trees in the rainforests. As the plant grows, it winds up and around the tree, attaching itself to the trunk with curved cat-like claws found at the junctions of its leaves. The Ashaninka Indians, who make these rainforests their home, have used the roots of the cat’s claw plant for thousands of years to cure illness and maintain health in the tribe.

Healers in the Ashaninka tribe attribute the healing properties in cat’s claw to the “good sprits” that live in the plant’s roots. In order to obtain these healing properties, the correct cat’s claw root must first be harvested. The Ashaninka healers know which cat’s claw to use; they can actually “see” the good spirits hidden inside the root of the plant before they collect them. Some cat’s claw plant roots have the good spirits. Some cat’s claw plant roots don’t. If the cat’s claw root with good spirits is mixed with any cat’s claw root without good spirits, the healing power is lost. While there are no visible differences in the plants or the roots, only certain cat’s claw roots possess the power to heal. And, only the Ashaninka tribal healers seem to be able to see them.

Amazingly, however, scientists who were given cat’s claw roots by the Ashaninka to study in the laboratory discovered that they were able to “see” the good spirits, too! Using high performance liquid chromatography, or HPLC, a laboratory process that identifies various chemical compounds, the good spirits of cat’s claw roots were revealed to actually be important medicinal compounds, called pentacyclic oxindole alkaloids (or POAs).

At the same time, the scientists studying cat’s claw found they could “see” the non-healing properties as well. Again, using HPLC, they also discovered the presence of tetracyclic oxindole alkaloids (or TOAs) in certain cat’s claw roots. While the POAs have very powerful effects in the immune system, the TOAs have different effects in the body, none of which help the immune system cells at all.

And, if the TOAs and POAs are mixed together (as, so often happens in the vast majority of cat’s claw products), the resulting product is useless to healing and health. The TOAs cancel out the action of the POAs, making the cat’s claw root extract ineffective. Even as little as 1% TOA content can cause POAs to lose their ability to beneficially modulate the immune system.


So it seems these Ashaninka shamans can somehow see which cats claw plants have the medicinal properties and which don't, and they refer to what they see as "spirits". Western scientists cannot understand how they "see" this, it seems the Western paradigm itself is blind to something which can be seen through the paradigm of the Ashaninka people.

This reminds me of the book DNA: The Cosmic Serpent, because it was the Ashaninka tribe that Jeremy Narby stayed with. Various Amazonian tribes have extensive knowledge of plant medicines and in some cases, Western scientists cannot understand how they obtained this knowledge because the statistical probability that they discovered it by chance is such that it would be completely absurd to believe that they made the discovery by chance. When they ask the people how they made the discoveries, the explanations they give are completely incompatible with the western paradigm. The most notable example is ayahuasca. It is a mixture of Psychotria viridis (chacruna) and Banisteriopsis caapi which must be boiled for 10 hours or so. Out of the millions of species of plants in the Amazon, what are the odds that they decided to mix those two particular species together, boil them for 10 hours and drink the resulting brew. Even if they had the knowledge of modern pharmacologies, what would be the odds that out of the millions of plant species in the Amazon, they discovered the one which contains significant concentrations of an MAOI (B. caapi) then somehow figured out that chacruna contains DMT (I've tried smoking it, snorting it and drinking tea, its completely inactive without an MAOI because it has such a low concentration of DMT).

On top of that, they have knowledge of what diet one should eat before ingesting the ayahuasca, in order to minimise the negative effects. Earlier western anthropologists believed this was just some superstitious taboo, but as science evolved, scientists gained an understanding of MAO and how compounds (like tyramine) in certain foods can interact negatively with MAOIs. The Amazonian shamans claim that they were given this knowledge by the plants themselves. According to Narby, one of the shamans he asked, told him that the first shaman to discover ayahuasca was a tobaquero and was instructed by the tobacco spirits on what plants to harvest and how to prepare the ayahuasca. In other words, he received the information in a vision induced by tobacco. For anyone who doesn't know, high doses of nicotine do in fact induce visions. Indian tobacco (Nicotiana rustica) contains up to 17 times as much nicotine as the kinda tobacco westerns use (Nicotiana tabacum). There is a tribe near the Peruvian Brazilian border (they're called the Matses) which uses a snuff called nu-nu, which is a mixture of finely powdered Indian tobacco and mapacho bark, they get someone with a tube to blow enormous quantities (half gram each shot) of it into their noses, until they fall unconscious. They say that after they lose consciousness they receive visions, and will see an animal arrive at a particular place, then later on they will go to that particular location and wait for the animal to come along so they can kill it.

Another one of these mysteries is curare, a preparation used by indigenous tribes to paralyse animals without poisoning the meat. Curare is a mixture of around 10 (I can't remember the exact figures) different plants which must be boiled together for something like 18 hours in order to become active. Indigenous Amazonians believe that the plants are intelligent and are in constant communication and that humans can communicate with the plant world too. There is a plant that grows in the Amazon which the indigenous people there use to treat snake bites. The plant itself resembles snake fangs, and one of the locals told Narby that this is no coincidence, he said that nature communicates to us in various ways. I didn't read the full book (DNA: The Cosmic Serpent), I haven't read the last couple of chapters yet but I remember Narby was theorising that there is a connection between some of the mythology and supernatural beliefs of these indigenous shamans, and real biochemical processes. I feel like I'm stumbled upon some connections that maybe nobody has yet made, which is why I wanna share it with others because maybe someone else will be able to see a big picture emerge. That discovery about the tetra and pentacyclicindole alkaloids in Cats Claw hadn't been made when Narby wrote his book. The reason I've researched the Matses is because they are one of the main tribes who use sapo (tree frog venom) as a medicine, and they are probably the most adept at it. I believe the Matses are the only tribe who use nu-nu.
 

Live plants. Sustainable, ethically sourced, native American owned.
 
Hyperspace Fool
#2 Posted : 6/14/2013 8:17:06 AM

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Well my friend... seems you have come to the right place.

I am sure you will fit right in here. Your interests and skill set should make you plenty of friends around here.

The Cat's Claw stuff is interesting. I had heard that it was only effective if harvested by a knowledgeable shaman, and your information makes sense. I was never drawn to use any of the commercial cat's claw supplements, as they never felt like they would do anything to me... I suppose this POA & TOA stuff is the reason why.

At any rate, make yourself at home. Avail yourself of all the joy and wonder that is the Nexus. I look forward to reading your posts on your discoveries. Entheogens are wild and woolly... and being a psychonaut is not effortless. Perhaps you could tell us a bit about your experiences with entheogenic substances?

Welcome to the Nexus.

HF
"Curiouser and curiouser..." ~ Alice

"Do not believe in anything simply because you have heard it. Do not believe in anything simply because it is spoken and rumored by many. Do not believe in anything simply because it is found written in your religious books. Do not believe in anything merely on the authority of your teachers and elders. Do not believe in traditions because they have been handed down for many generations. But after observation and analysis, when you find that anything agrees with reason and is conducive to the good and benefit of one and all, then accept it and live up to it." ~ Buddha
 
Entheologist
#3 Posted : 6/24/2013 7:13:43 PM
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Sorry I haven't replied in such a long time. I have a bit of an issue (amphetamine withdrawal) at the moment which makes me lethargic most of the time. I don't have a great deal of experience with entheogens, I haven't done DMT yet but I have some experience with psilocybe mushrooms, salvia, cannabis (I'm prone to cannabis induced psychosis so it hits me like a full on psychedelic) and various other unusual states such as sleep paralysis, lucid dreams, sleep deprivation and psychosis, all of which have had a profound impact on my understanding of the mechanisms of reality. While I have no experience with DMT, I tried 5-MeO-DALT recently which was very interesting. My mindset (i.e. my emotions and way of thinking) was more or less unchanged, but I was hallucinating heavily. I would stare directly at an object and watch it shape shifting into something else every second or so. It was really interesting because there was a set interval of time between every time the object shape shifted. I stuck to smoking low doses (no more than 10mg at once) out of fear, I'm guessing higher doses induce profound changes in consciousness, the doses I did seemed to mainly alter my visual perception.

Besides the ones I've mentioned, the only other psychedelics I've done is iboga, but the dose I did (10mg of root bark) wasn't enough to induce visions, just induced a great deal of euphoria and some minor visual hallucinations (tracers). Actually I've done AMT and it effected me in exactly the same way as iboga for some reason. I have a great deal of experience with other classes substances (i.e. stimulants and sedatives).
 
Hyperspace Fool
#4 Posted : 6/25/2013 9:06:11 AM

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Very interesting.

Sorry to hear about your amphetamine abuse issues. Such stims are not recommended in general for this very reason, but are especially counter-indicated in people who are prone to psychosis. As you seem to know, sleep deprivation is no joke.

Well, I sincerely hope you get through this rough patch and find yourself in a better space.

As a side note, I think cannabis is a psychedelic for anyone who has no tolerance for it. We often forget this, because most ganja users are fairly regular and thus get pretty mild effects from it. If you aren't in a regular flow with cannabis, better you take really micro hits. A single quarter lung full of grass is plenty to start with IMO. People tend to overdose trying to keep up with their stoner friends.

Anyway, welcome once again. Be well.
HF
"Curiouser and curiouser..." ~ Alice

"Do not believe in anything simply because you have heard it. Do not believe in anything simply because it is spoken and rumored by many. Do not believe in anything simply because it is found written in your religious books. Do not believe in anything merely on the authority of your teachers and elders. Do not believe in traditions because they have been handed down for many generations. But after observation and analysis, when you find that anything agrees with reason and is conducive to the good and benefit of one and all, then accept it and live up to it." ~ Buddha
 
Entheologist
#5 Posted : 6/25/2013 4:36:39 PM
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Thanks. The bright side is I have an opportunity to use myself as a guinea pig and experiment with potential ways to accelerate the recovery process. I've been experimenting with Amazonian tree frog venom and other unconventional medicines. I recently heard some very good things about noopept, and am going to order some to experiment with it. NMDA and AMPA antagonists block the process of developing tolerance, so my theory is that enhancing glutamate activity when you are in withdrawal can accelerate the recovery process. Ampakines and racetams enhance glutamate activity.

Its not just amphetamines that I was addicted to, I was also using sedatives including opioids, benzos, GHB/phenibut and trazodone to counteract the insomnia, and got mildly addicted to each of these classes of substances, so I did a serious amount of research on dependence and withdrawal of various classes of substances. My experience with all this has given me the desire to help others who are dependent on psychiatric drugs to function normally.
 
Hyperspace Fool
#6 Posted : 6/25/2013 5:16:17 PM

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Entheologist wrote:
Thanks. The bright side is I have an opportunity to use myself as a guinea pig and experiment with potential ways to accelerate the recovery process. I've been experimenting with Amazonian tree frog venom and other unconventional medicines. I recently heard some very good things about noopept, and am going to order some to experiment with it. NMDA and AMPA antagonists block the process of developing tolerance, so my theory is that enhancing glutamate activity when you are in withdrawal can accelerate the recovery process. Ampakines and racetams enhance glutamate activity.

Its not just amphetamines that I was addicted to, I was also using sedatives including opioids, benzos, GHB/phenibut and trazodone to counteract the insomnia, and got mildly addicted to each of these classes of substances, so I did a serious amount of research on dependence and withdrawal of various classes of substances. My experience with all this has given me the desire to help others who are dependent on psychiatric drugs to function normally.

Don't do shitty drugs.

And yeah, noopept rocks.
"Curiouser and curiouser..." ~ Alice

"Do not believe in anything simply because you have heard it. Do not believe in anything simply because it is spoken and rumored by many. Do not believe in anything simply because it is found written in your religious books. Do not believe in anything merely on the authority of your teachers and elders. Do not believe in traditions because they have been handed down for many generations. But after observation and analysis, when you find that anything agrees with reason and is conducive to the good and benefit of one and all, then accept it and live up to it." ~ Buddha
 
Entheologist
#7 Posted : 6/25/2013 7:41:10 PM
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The way I see it, psychoactive substances are tools. Whether they produce good or bad, depends entirely on how they're used. Using "shitty drugs" long term causes harm to the brain, so one is better off looking for alternative ways to accomplish whatever therapeutic it is that the drugs temporarily induce. I had a problem with drowsiness before I started taking amphetamines (its why I started taking amps). Now that I quit the amphetamines, I need to find a solution. I'm thinking ayahuasca might be the way to go.
 
Hyperspace Fool
#8 Posted : 6/25/2013 8:09:52 PM

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Well ayahuasca certainly qualifies as a "good" drug. I hope you find what you are looking for.
"Curiouser and curiouser..." ~ Alice

"Do not believe in anything simply because you have heard it. Do not believe in anything simply because it is spoken and rumored by many. Do not believe in anything simply because it is found written in your religious books. Do not believe in anything merely on the authority of your teachers and elders. Do not believe in traditions because they have been handed down for many generations. But after observation and analysis, when you find that anything agrees with reason and is conducive to the good and benefit of one and all, then accept it and live up to it." ~ Buddha
 
cyb
#9 Posted : 6/25/2013 8:44:34 PM

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Moderator | Skills: Digi-Art, DTP, Optical tester, Mechanic, CarpenterSenior Member | Skills: Digi-Art, DTP, Optical tester, Mechanic, Carpenter

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If you're looking to counteract drowsiness... Noopept is definitely the way to go.
20mg in the mornings will keep you alert and focussed all day.

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