New member, first post...long time "peruser" of the wealth of information this community provides.
Seeds straight (heavenly blues or baby woodrose from hawaii)are active, however I too wish to do away with cramps, vascular constriction, nausea and vomitting.
Yohimbe and ephedra (personal experience) alone I feel are uncomfortable, woudln't combine them together or with anything else. Personally, I wouldn't mix them.
Instead, took the path of chemically extracting the LSA. I ran into an error somewhere along the way, any feedback from anyone would be greatly appreciated. Trying to learn from mistakes. The tek can be found in LSA section posted by Kash. I'd ask there, but I cant post as I'm new.
Basically the procedure uses
-3 Anhydrous Acetone filtrations (3 hours of agitation between filtration), discarding seed pulp after 3rd filtration.
-All 3 filtrations then evaporated fully to a fine layer of crude LSA extract that came off in thin semi translucent brown sheets once scraped.
-After collecting scrapings, citric acid was added to distilled water to ph 4 (shooting for 3-5) then added to crude extract. 30 minutes in-between filtrations of that solution left me with LSA citrate that still had to be defatted.
-Then, defatted with 4 VM&P naptha pulls (separating layers with seperatory funnel saving aqeuous layers.
-After all aquous layers combined, solution was basified using drop by drop ammonia. I tested ph with litmus papers, however it took more than expecting (dropping drop by drop for 45 minutes while stiring with glass stir rod. (Perhaps that was the mistake?) (small amount didn't seem as small as expected to me, could have destroyed LSA) Finally, I knew it had been based enough when the color of solutin changed from light yellow to orange to algae green and ph paper said 9. If it turned blue it was based too much, however it only turned blue after it had been left aside to sit after extraction was fully completed and aqeuous layer had been pulled of all alkaloids theoretically.
-Toluene was added quickly and agitated for 20 mins, then pulled and separated using seperatory funnel. After 3 Toluene layers, the fractions where evaporated. The problem came when I checked the dish and there wasnt any residue of any kind or anything.
Any feedback on the topic at all would be greatly appreciated, I'm too stubborn to give up so try and try again
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Also, I apologize if this wasn't posted in the right section and for being a bit lengthy. I'm a new member.
Peace