..haven't read the links yet, but i recal that while R. Strassman found DMT had no physical tolerance, some subjects (given administrations repeatedly) felt that the subjective effects would become diminished..
J.Ott in Pharmacopeia (from memory) suggests it is better if 2-4 hours have passed between vaporizations..
..there could be Cross-Tolerance between LSD or psylocibin and DMT, as there is between LSD/psylocin...

mmmm well I am asking because I am having trouble with this. Haven't been able to feel much lately.
All post are fictional.

Try synergy.

Make changa.

Eat LSD and then smoke changa.

Or eat some Mushrooms and smoke changa.

Experiment with synergies. I've found they allow me to go deepest. It may help you as well.

Drink ayahuasca and then smoked DMT/Changa!

Hey fellow travelers,

I'm now thoroughly concerned I developed a tolerance to DMT. I was under the impression you could'nt get a tolerance unless you did it several times daily. I've only been doing it a month now, usually once a day, twice a couple times. With my only true breakthru following the one time I actually stopped for 2 or 3 days. Tried double that dose next day and did'nt even come close to breakthru.

What I mean by tolerance is I don't see colors, or really much of any visuals, and the super profound effects have been dampened drastically. Don't get me wrong, I still have weird trips every time. I like it too much to let it turn into that so I am now on an indefinate break, and am going to put a limit to maybe once or twice a week when I resume.

So I'm curious if anyone else has experienced this? Or what more experienced travelers think about tolerance?

have you changed any of your habits? Have you started taking herbs like st johns worth or something?

Nothing different.

Honestly i dont know how people can do it that often due to the other tasks that need to be done in a day and how powerful each experiance can effect you.

Must have a lot of balls.

There is really no tolerance, but many reports of people being denied access to hyperspace.

IMO you are journeying too much, and hyperspace is telling you to take a break.

I'm sure you know that too.

Make sure your lighter fluid (or butane) in your lighter is refreshed to ensure proper temperatures. I went through a couple months spree of doing it every day or often multiple times a day. I don't think it's so much of a physical tolerance issue as much as it is an integration issue. It seems from my experience that if you do it so regularly that you don't allow yourself much time to integrate the individual experiences. There is a sort of "intelligence" about DMT, and for some reason when it feels that its lessons have been integrated, it will allow you further.

Believe me, it's nothing like that. I still have the same fear/ aprehension b4 each trip. I've already had a few not soo pleasant experiences. As far as things that need to be done in a day... Due to my poor decision to drive intoxicated, I've been a prisoner to my house for the past couple months and 2 weeks to go. I truely believe spice entered my life at this bad time for a reason. If it had'nt I think the isolation and boredom would've drove me over the edge. Not to mention I'd probably be using again because of it.

But yeah, my honeymoon period is over. I knew from my first experience I was a lifer, so I definately don't want to abuse the privelege and be denied access ect. What I meant about the tolerance was like the reason I would only drop acid once a week or less. It was always like the longer I waited the better it would work. I'm just guessing DMT is gonna treat me the same.

Maybe you should read alittle about what receptors are affected while doing DMT. Its pretty normal with every psychedelic substance you use that the effect will decrease by heavy use in a little period of time. Wait 1 or 2 weeks and try again, and i promise you that you will manage to get a breakthrou again.

Hey guys

What are your experiences with tolerance? I've been hitting the spice a fair bit these past days, recording and taking notes, trying to understand this alien world. Should I take a break for a few days/weeks?

I really don't think the dmt faires would be angry at the frequency of my use, as I've seen suggested elsewhere. This is purely a journey of discovery and understanding I am on - I think they would appreciate that. :-)

You are the judge here, but you may have difficulty with integration, it may take you a really long time to 'come back' to this 3rd dimension if you do too much within a few days.

So there is no real proof that you build up tolerance if you smoke once a day?
Instead I'm to believe that I'm being denied to access hyperspace, but where's the evidence for that?

Don't get me wrong. I find the idea very interesting but I simply want to know how people can know this? There might be a possibility...but how can one really tell? Perhaps the DMT entities told them? Or that they somehow can feel it. I don't know, but I'm sure they have their reasons for believing so and I would like to hear them.

I myself believed this since I didn't get breakthrough for a while, but it turned out that it had much to do with my smoking technique..

The reason for why I react to this is because I think I developed tolerance to DMT after been using it once a day for 2-3 weeks. But according to some I am wrong about that.

I just want to hear your thoughts about this.

Tolerance or being denied access - or we simply don't know? Perhaps a combination of both.

Strassman's dose/response study is pretty strong evidence that DMT create no meaningful tolerance to itself...

I should have checked his study before posting. I did a google search now and found this:

"The tolerance project in which subjects received a high dose of DMT four times, at 30 minute intervals. This latter study, which did not demonstrate a reduced response after frequent dosing (i.e., there was no tolerance),"


But I guess this study is more complete in his book? Do you know where I can found the complete study? I want to know for how many days they did this etc.

I'm sorry to contradict so many that have said otherwise, but yes you certainly can build a tolerance to DMT.

The tolerance build up and diminishing process for DMT exhibits similar patterns to that of LSD and other psychedelics but on a different scale and length of time. The reason that it often does not seem like the tolerance has built up is because tolerance diminishes rather quickly. I can say this with absolute certainty because I have experienced it consistently throughout several repeated experiments with my personal Spice Journeys.

As I have discovered, if I go about 6 months without any Spice Journeys to cleans my system, then go through my Spice Journey, when I reach about 6 to 8 hours of repeated smoking of the freebases, which can be anywhere between 30 and 50 doses, there is a point in which tolerance levels are so high that it does not matter at all how big of a dose I smoke. It does nothing beyond irritate the throat and lungs. At this point I have pressed so far, in the name of scientific curiosity, as to vaporize 100mg doses back to back with only enough time between each to catch my breath. The maximum number of 100mg doses that I have ever vaporized back to back, one after the other, after having reached this "brick wall" was 12. (Yes this is 12 consecutive 100mg doses vaporized. It is not a typo, and it is not an exaggeration or embellishment.) In absolutely no circumstance was I ever able to get any DMT effects from vaporizing any amount of DMT once I hit this "brick wall of absolute tolerance and immunity", even when this experiment was repeated. The only thing that was achieved by repeated vaporization of DMT immediately after reaching the "brick wall" was lightheadedness and a slight head rush from all of the inhaling, a sore throat and lungs, some restricted breathing for a while afterwards, and a nasty headache.

Through further experimentation additional discoveries were made. After reaching that "brick wall" the absolute tolerance begins to diminish. Once that "brick wall of absolute tolerance" was reached, I found that if I wait 30 minutes to an hour, then vaporize 100mg, I can at least feel a little something. Usually it is not much more than a slight rush or load that washes over the body but occasionally I would get about 5 or 10 seconds of visuals. Additionally, if I wait longer, then I am actually able to achieve a good breakthrough somewhere between 2 and 5 hours after the "brick wall" was reached. However, a second dosing within the hour is a gamble, and a third dosing very rarely results in a breakthrough, and sometimes doesn't even result in any visuals.

Furthermore, when I wait a day or two after having reached that "brick wall" before I go on another Journey, then, within 2 or 3 hours (approximately between 10 and 20 doses), the entire Journey comes to an abrupt end as I hit the "brick wall" again. Additionally, if instead I wait a week or two then I am able to go 4 to 6 hours before reaching the "brick wall".

I have also learned that there is a pattern to how long it takes to reach the "brick wall" and it depends on how often I take my Spice Journeys. If I take a Spice Journey regularly once per week then the Journeys will balance out and they will last about 4 hours. If I take regular Journeys once every two weeks then the Journeys last at least 4 hours with most being able get to the 5 hour mark and sometimes as much as 6 hours. If I take regular Spice Journeys once a month then I don't have a problem reaching at least 6 hours or more. But, it usually takes at least 4 months before I can reach 7 or 8 hours again. Finally, the longest Journey that I have ever been able to achieve was about 9 hours but it was only after about an 8 month cleansing and it was assisted by pharmahuasca in addition to the usual fumahuasca.

This paragraph is just to make some clarifications regarding these experiments and my Spice Journeys. First of all, my Spice Journeys are not practiced in the typical manner. Generally, when I begin a Journey it is my intent to go very deep into hyperspace and remain well beyond the breakthrough barrier for as long as possible in the next 5 hours or so. Additionally, by the time I recognized the tolerance build up and decided to experiment with it, I was already beyond the point that I quit worrying about measuring my doses. The only time I measured doses was when I was specifically trying to discover how much DMT it would take after having reached the "brick wall". What I can say is that over the length of time that my Journey lasts, the doses start out smaller and tend to get larger and larger until I reach the point that I can't fit any more in my lungs. At that point the doses just occur more often until I reach the "brick wall". Additionally, I will also note that my Spice Journeys during these experiments were initially and primarily done with fumahuasca using a freebase extracted from rue, however, similar results were achieved with strait white DMT as well, however, the time lengths of the Journeys were usually a little shorter. Finally, I will say that since then I have begun using a combination of fumahuasca and pharmahuasca. I have not taken notes the way I did when I was more actively 'experimenting' but so far I still see similar results but with the addition of pharma it does seem to make it easier to stay in breakthrough hyperspace during the time periods of the Spice Journeys.

Now to bring this to a close I will leave you with a short description of the "brick wall of absolute tolerance and immunity". When I reach the "brick wall" I know it immediately. It is really kind of weird. We all know how quickly the climb can occur when smoking pure DMT. The "brick wall" is like the opposite of that effect. I have almost always been in a very deep and intense breakthrough when, all of a sudden, I just drop out and within 30 to 45 seconds I go from complete breakthrough (out of body, beyond ego death, existing beyond the universe) to completely sober and strait even able to walk a strait line heal to toe, toe to heal forwards and backwards. The one good thing is that the "afterglow" still remains.

Final Disclaimer: In absolutely no way am I promoting or encouraging anyone to experiment with DMT, fumahuasca, or pharmahuasca, or any combination thereof, in the same or similar manner or method of which I tend to practice. I recognize that the majority of people who experiment with these substances do not use them in the same way that I do. These are very powerful substances with a significant amount of variance in how they can affect different people. What is comfortable and enjoying for one person may be unexciting and boring for another person and what one person may find to be the perfect dose resulting in the ultimate most beautiful experience may very well scare the holy hell out of another person. So please, if you are to dose these substances, experiment wisely and cautiously to find what is right for you and allow others to do the same. And when another person prefers a different dose, then neither condemn, nor admire them for that. Please except that we are all different and sometimes we prefer different things.

hi this is my first post.....I am fairly new to spice, but I can agree the second break through I had I don't remember to much about the trip, but when I came back I had a hard time adjusting, I was not sure what was real I did not even know there was an outside to the room.....let alone a world...universe....lol.....it even scared me a bit.....I think I may of even had an ego death.....im not to sure......I know it was all red and yellow and it felt like everything was being ripped apart......then it was like some 1 turned the lights on everything had really bright lights around them and looked very futuristic I thought every 1 in the room(my friends) was part of me (emotions or something like that and I was questioning them).....like is there an outside...but it took me a few days to feel right again.....after that

That might be how it goes for you, but that's not how it goes for me. I have tried smoking spice at all sorts of intervals, including smoking while in the middle of an experience, at the tail end, immediately after, 5 minutes after, 15 minutes after, an hour after, 2, a day, two days, etc...and I find there to be no clear tolerance pattern. I can achieve high states at any interval, and I can be "denied" at any interval.

It should be noted however that yes, as was the case with Strassman's tolerance studies, it was shown that there was no tolerance to IV DMT, however having said that, I have heard cases to be made in regards to how repeated inhalation of the DMT vapor throughout the course of a day will cause the blood vessels in the lungs to constrict so as to take in less of the inhalant, and could possibly be a source of tolerance that would not be found in the IV study. Inhaled DMT is simply something of such a tricky and ambiguous nature at times (as opposed to IV - you know that the entire dose will get into the system at least as opposed to smoked/vaped DMT where any number of things can happen from the DMT condensing on the glass/wood/metal of the smoking device before reaching the lungs, to not holding it in sufficiently, etc...).

Please re-read the "Final Disclaimer" as I recognize and specifically state that each person is different. Also try to keep in mind that very few people actually go through 2 to 4 grams of DMT in a 4 to 8 hour period during their twice monthly Journeys. In 5 years of taking Spice Journeys I have known only 3 other people that surpass 1 gram in a sustained Journey, and only one of them went through 2 grams. What I can say is that the gentleman that went through 2 grams in a single sustained Journey on a regular basis also described the phenomena in which sometimes reaches a point of complete immunity to the effects of DMT.

I am not suggesting that tolerance build up is even relevant to most people. In fact, I believe that the majority of people will never reach the point in which they recognize a significant tolerance build up, and even less will ever experience the "brick wall of absolute tolerance and immunity". However, given the results of my own experimentation and other confirmations, it is not unreasonable to conclude that as consumption through inhalation approaches 0.5-1.0 grams per hour for 4-6 consecutive hours the majority of people will reach a temporary but absolute tolerance and complete immunity to the effects of DMT.

Just to be clear, the primary reason for submitting this information is simply for academic and documentation purposes. I'm not trying to argue and say that anyone has developed a tolerance, simply that given enough of any substance the body will usually do one of a few things and the most common are they either build a tolerance or they will die.