Mo' Knowledge Mo' Power, glad to be here, hopefully in a greater capacity soon, as my job hours drop from 60-80 a week to around 40/week supposedly in 2 weeks.
I would agree that tolerance is subjective, but of every person I have tripped with I have always needed the most of everything despite never being the person with the most mass, often having less experience and potential tolerance with the substance of interest. That being said, I have surmised the only quality I can think of that would produce this affect would be my over active sympathetic nervous system (OASN). This could be physiological or behavioral. Many people develop anxiety with an OASN but I'm calmer than anyone I know ( a forced behavioral adaptation I would guess). Anyhow, If not that physiologically, with higher adrenaline, higher cortisol levels, higher heart rate, metabolism, I would imagine, either the general flurry of hormones and metabolites my body over produces mutes the effect of drugs to an extent in comparison to a more average person. I.e. there is no reason I should be able to outdrank my bar hopping 225lb friend when I drink once a month and weigh 50 lbs less. Yet this is the case. But this could be behavioral as well I suppose, self control, presence of mind, etc.
Thoughts? Similar experiences anyone?
And the actual achievements of biology are explanations in terms of mechanisms founded on physics and chemistry, which is not the same thing as explanations in terms of physics and chemistry.
~Michael Polanyi