Any shroom growers in the house know what these are, if you dont its basically a glass test tube with a rubber top that you can suck the air out with a syringe(again the shroom growers have these laying around).

Anyway just curious if freebase dmt would keep good under negative pressure in a test tube?

What about dmt salt?

Would it be ok to put said tube in freezer or would a drawer or box be ok?

DMT will keep better in those containers after applying vacuum to them because less oxygen will be present so the DMT will be less likely to form DMT N-Oxide. Also freezing it (the freebase) would help keep it from decomposing.

You wouldn’t want to freeze a DMT salt though. Many salts are not stable when frozen.

Awesome thanks, they tend to be super cheap if anybody thinks they might want some.

Any idea why salts are less stable when frozen ron?

Are we talking about dry salts or salts in solution. SWIM cannot see how dry salts can degrade when kept in the freezer, but he can understand why salts in solution (esp. water) can be damaged by frezing.

Infundibulum, I don't really know the reason for it. The pharmaceutical industry nearly always recommends that salt forms of drugs are not kept frozen. I’m just repeating what I’ve read from research about various pharmaceuticals in salt form. Maybe someone else here knows the reason for the pharmaceutical industries recommendations for not freezing salts.

I've seen MSDS papers for 5-MeO-DMT in salt form which recommended NOT freezing it. I assume they know what they are talking about and this probably also applies to DMT.

Quite a lot of compounds degrade when kept frozen. Vitamin C for example should never be kept frozen. I don't know why, I wish I did. I don't like knowing the facts without knowing the reasons behind them.

Please view the attached MSDS for FREEBASE 5-MeO-DMT. The recommended storage temperature is 2-8 C, NOT FREEZING! I'm sure there's a reason for that temperature range, but I don't know the reason.

This is what it says in section 7 in the MSDS from SIGMA-ALDRICH for freebase 5-MeO-DMT in dry powder form:

SWIM sees the point. Yes, it is quite frustrating not knowing why and it is difficult to trace the reason for the recommended (from the suppliers) storage temperatures.

SWIM has the tendency to disagree with the recommendations that come from the companies. Not always but sometimes. In many occasions he has stored materials in the freezer while the company recommends fridge storage and he has found no loss in quality. He's talking about storing biomolecules such as purified antibodies which are quite prone to degradation resulting from temperature differences.

SWIM believes that no good/accurate studies are always performed when a company decides the temperature storage of an X chemical. He thinks it usually goes like that:

1) some of the X substance is kept at room temperature, some in the fridge and some frozen.

2) after a year or so quality of the product is assessed.

3) and if fridge storage is as good freezer, then fridge storage is recommended.

The MSDS for freebase 5-meo and (the attached pdf) do not state something like "avoid freezing". Strassman as far as SWIM remembers was keeping his dmt fumarate in the freezer.

In the end not much point arguing this kind of stuff. It would be quite interesting to see whether salts kept in the freezer lose potency compared to those kept in the fridge. And doing this kind of studies (i.e. bioassays) is always fun

Ha! Those look familiar! SWIM found a few of those in an abandoned house in old vet's med-pack, along with a kickass jacket that fit perfectly. SWIM's used them for storage ever since.

I just have a hard time believing that the recommended storage temperature from SIGMA-ALDRICH for 5-MeO-DMT is wrong or simply a guess. If they didn't know the storage temperature they would probably have left it blank as they've left most other MSDS fields blank that are lacking information. As a big time seller to research facilities, SIGMA-ALDRICH would get serious complaints from their customers if they gave out false information.

Well, I didn't say sigma is wrong. A recommendation such as "store in fridge" is fine and quite sufficient for practical purposes. Sigma does not say "DO NOT FREEZE", which means that they have not really assayed the effect of freezing on the product.

SWIM once ordered an antibody from another big player company, its MSDS said "DO NOT FREEZE" so he called the company and he asked them what would actually happen if he does freeze it. They said that it won't hurt, even thought repeated freeze-thaw cycles will damage the product. The customer services actually recommended freezing the antibody in aliquots, so a "single dose" can be thawed and used without compromising of the total product.

And they were actually right. This product still frozen is still working for SWIM after 4 years. The MSDS was stating the expiry date is one year after purchase, recommended storage in the fridge.

Basically what I am trying to say is that MSDS are not be believed as a holy text or something. They do contain useful information but there are much more to these.

Until I see a test that shows otherwise, I think it's best to trust the recommendation from SIGMA-ALDRICH.