This fall, I'm facing another surgery, just had one two weeks ago too, and am spending a fair amount of time contemplating my life, where I've been and where I'm headed, while I'm sitting here recuperating. I am hoping to do some microdosing of just caapi, by that I am thinking 10-20g baby steps and increasing as I feel comfortable with it- new territory for me.

With that in mind, the pre-surgical check list has a huge number of foods, herbs, drugs etc to avoid before surgery... Of course caapi and dmt are not on the list, but I am considering the psychological spiritual aspects of dosing with caapi... Would it maybe be a good thing for deeper contemplation before hand, as this surgery coming up makes me sad? Should I wait until I am feeling pretty much back to normal (whatever that is) before I drink again afterwards?

Anaesthesia can really take me down, make me weak, and I am pretty cautious in general around these kinds of things. Does anyone know of any specific bad interactions with caapi and anaesthesia? Suggested wait times before/after? I have read all the different drug interaction threads, lists and links I have found here- so wondering if anyone has any direct experience with this.

I see this forced rest period as a time to meditate more, contemplate my life more, and create art more frequently... having some guidance/direction/protection from caapi spirit seems like a good thing. I've had an awful lot of life changes in the last couple years and haven't really taken the time to catch up with my Self, seems like this would be a good thing, the small doses of caapi, in moderation.

I know I'm not ready for more than this right now, but even a little seems like I should approach as best informed as I can, with my eyes wide open and aware.

One of the guidelines for this place is not giving medical advice. This question is inherently medically related. Very few, if any, of us are qualified to answer such things, and even a doctor would probably be at a loss since there is probably no test data.

So my words of wisdom are, better safe than sorry.

These plants are special and always seem to make up for any missed time. Any time I have anything to worry about, and I go ahead and do something, the experience is tainted. When the time is right, you can feel it.

How soon before the surgery are you thinking about. I'm obviously not a doctor so I want give advice on this but if your talking about a week or more I doubt anything would still be in your system. Maybe research time maoi stay active in the body. hopefully Corpus Collosem could answer that.

Anesthesia is a broad term which can be produced by a range of compounds of different inherent chemical properties.Then theres the issues of pre-meds which can include anti-emetics; induction of anesthesia which could be with an agent such as alfentanil and lastly maintenance of anesthesia which could be brought about by volatile gasses, barbiturates or other unique agents.

Then theres the issue of intra-operative complications like profound hypotension which may need IV pressor agents such as epinephrine.

In essence, I would suggest that you would be foolish to be taking MAOIs when you may need to have administered to you agents which just go badly with MAOIs.Plus taking stuff and not letting the gas-man know about it is just plain wrong- both for your and their best-interests.

I might be misunderstanding, but I think thequestion is more like is it ok to try some caapi in the weeks leading up to the surgery, not during the surgery itself, and how long before the big day should the caapi use be stopped in order to be safe. From what I've read it's supposed to be ok to go off the MAOI diet within a day or two after taking a reversable MAOI, so would the same hold true for possible drug interactions as diet? Or would being off it for something like a week be better?

^^ I personally would not use MAOIs for at least a week pre-op; using them after would depend on whether or not I was put on any meds which may not go well with MAOIs.Assuming no potentially interacting discharge medication, I would not take MAOIs for period a of about 5-7 days.Most drugs used in modern anesthesia do have relatively short half-lives.

Thank you for your input corpus callosum, and thanks also CrazyHorse for clarifying what I was trying to ask. Yes, I was looking for specific info about how long it would take to clear the MAOIs before surgery, and other drug interactions to consider that are not already listed in the threads on this site, such as epinephrine or barbiturates that may be administered while under without my knowledge. The next surgery is in two weeks, and the latest I would even consider ingesting anything is this weekend- 10 days out.

I try to be very clear with my doctors about which drugs they administer, and I try to stay informed about what they actually give me- including the anti-emetics, as some affect dopamine levels, and I won't take them.

I have a pretty good relationship with my anesthesiologist, and could tell him about the MAOIs if I needed to. But at this point, it is likely that I won't need to.

Afterwards, no post-op drugs, just can't handle them- just good ole tylenol.

So thank you for helping clarify, I do appreciate it.

Edit: I found this list of drug interactions with MAOIs in "Health & Safety" posted by MelCat, from Source: http://forums.ayahuasca....pic.php?f=12&t=14761
and I made it into a pdf for myself for quick reference.