When dealing with 1 g hcl after anhydrous acetone washes what ratio/ volume of acetone to water is best for freeze precip?

Or should this be done instead of dry acetone washes


Phlux re-x for hcl says to have already cleaned your salt before dissolving in a little bit of water, then add "copious" acetone, stirr, decant away from precips and evap the decanted solution.

Is this a feasible method in your eyes?

I think if you have already cleaned your product, you will end up with a cleaner re-x. For re-x, Swim likes to add excess acetone and heat with stirring, then drop in water while warm until all salt dissolves, and then let cool.

thanks kash, after the solution cools, decant and evap the decanted solution?

i've only done this w/ mek, but tone should be same:
take dried hcl salts, dissolve in boiling acetone, you might need to add 1-2 small drops of water to get it to all dissolve
cover, and allow to cool in freezer
filter needles from ice cold solution, rinse w/ ice cold acetone

If water is added then the solution decanted will contain some amount of mesc. Just save it for later re-x s I suppose

Not necessarily, becuase when you heat it and add just enough water for it all to dissolve, you are making a supersaturated solution that wouldnt be able to hold salt at low temp. There would likely only be a very trace amount left in solution after the crystals crash out if anything.

@ dg - Does recrystallized hcl form needles too? or is that just sulfate?

this entire project will be postponed until active cacti are used, everything ive been working with has been truly impotent (.03%)

also the effects of the hcl came on in minutes and lasted about 6 hours.... it didnt quite feel like mesc hcl...

just to confirm - on my re-x - the solids that are left are the actives - one can scrub the evap for more actives after this.

what does this mean?


mew will try another round with fresh xylene before he takes a break from this powder that seems to yield poop and a half

mew was taking his mesc hcl and washing it in boiling acetone, after everthing is mixed and the acetone dosent get any darker he puts it in the freezer and lets it settle/freeze, then decants away from the mesc hcl which is remarkably cleaner than just a frozen acetone wash


the mesc hcl is dissolved in hot water and filtered finely

this is evaporated and placed back into a vial with fresh acetone, boiled and has water added dropwise until the hcl dissolves (stirring is suggested). this is then placed into the freezer and let freeze/precip. the mesc hcl sticks to the vessel and (use a filter to pour the acetone through anyway) and the mesc hcl is rehydrated with warm water and evaporated on a hot plate to yield much cleaner mesc hcl (room temperature evaporation yields nice crystals btw)

all acetone washes are to be saved and evaporated later to ensure nothing is lost

fasa on xylene seems to precipitate a decent amount from a half kilos worth of tea... barely into the process yet there is a thick blanket of xtals


perhaps success after all

an amateur move on my part, i decided to filter out what had already precipitated and found alot of it ran right through the coffee filter, leaving me with a fasa+xylene n fum precips n a dirty xylene soaked filter full of fums, owell..

all pulls are being combined in and salted and let settle then ill either have to decant or use a finer filter, we shall see...

but as it seems the project is not lost

what i mean is

the solids left are mescaline the impurites and a tiny amount of mesc may be in the washing's
so one evaps the washings - then repeats the proceedure again - to get the last of the mesc out of the washing.

just making sure no mesk is thrown out.

3x200ml xylene pulls salted with fads yielded 1 g fumarates after ther were cleaned with minimal distiller water, best result yet , hower the cactI is still some of the weakest I've seen



After fasa I'll salt with hcl solution to ensure all mesc is removed. Mesc hcl is insuble in both xylene and acetone and will convert and spare fums to hcl.

the rest of the pulls were salted with hcl and yielded 2.25 hcl + 1 g fumarates (which was tested and great!!!!!)

so 3.25g from 1/2 kg is what i got, but theres definitely room for improvement,

for example using a pc instead of my multiple hot water pulls/decants

will test another 500 g to see if i can increase my yield!

old solvents dont work as well as fresh

heres a thread i wrote about my comparison of old used dlimo to fresh xylene

d-limo: limited use

So in defining the 'Best' mesc extraction tek, we are looking at procedure time, cost, scalability, and labor involved perhaps? We can safely assume yield should be about(not exactly) the same for each tek if done right? The best tek could technically be different for different people then depending on what their goal is.. maybe a rating scale should be presented instead? Something like this maybe:

(BTW im making these figures up from my head, may not be accurate)
Mescaline Extraction Tek Scale

Acid Cook--------------------- Time:Medium Cost:Low Scale:Large Labor:High

Acid Pressure Cook------------ Time:Low Cost:Low Scale:Large Labor:Medium

Alcohol Soak------------------ Time:Medium Cost:Medium Scale:Medium Labor:Low

STB Lucid's Sunflower Oil Tek- Time:Low Cost:Low Scale:Small Labor:High **Hazardous

STB 69ron's Dry Tek----------- Time:Low Cost:High Scale:Small Labor:Low

?Acid Soak w/Pectinase?------- Time:High Cost:Low Scale:Large Labor:Low

?Acetone Soak?---------------- Time:Low Cost:High Scale:Small Labor:Low


People who have worked with the individual teks could contribute their opinion to the mesc tek scaling to provide the most accurate depiction. The reasoning for the tek's individual ratings could be justified in following sections. Then, depending on what the future extractor's priorities are, they select a suitable 'best' method for themselves. What are some opinions?

I'd like someone to please explain this tek to me. I've had to clean up the result of this mess for some kind souls, this has to be the most pathetic excuse for an extraction tek I've ever seen.