I will chime in to say, I've been sort of fascinated with growing all these plants (I grow mandrake, brugmania, various datura strains and belladona and henbane as well).
I also use them in very low dosage to microdose, and always NEVER go past the threshold effect which already start to be annoying (dried mouth and slight dizzyness).
I use mainly mandrake root in capsules, or soaked in alcohol with salsaparilla.
I use belladona as well cause scolopamine is know to have a stimualtive effect at first, wether scolopamine is more sedative.
Both are anti-nauseous and they are great addition to most brew or extract (cacti and it's extracts, mushrooms-psilocibe and others, amanita muscaria, ayahuasca or pharmahuasca).
They do seem to add a little something to the experience, more depth, more darkness also which is why it is highly discouraged to poeple with little to no experience with other plant medecine or psychedelic in general.
In my experience I'll say that these nightshade like amanita is really only possible for experienced psychonaught who really know the dosage of these batch of plant (the dosage varie greatly depending of the plant itself, the season, the part), you could easily no feel anything from 5 big brugmanisa leaves one day and try two tiny brugmansia sanguinea leaves and be already in dangerous zone with lots of dizzyness and unbalance.
Always watch out if you really want to dig and use with the same precaution as RC's:
- Do an allergy test on EACH new batch of material
- watch results for 24 hours (it can take long to kick in, never urge to redose)
- slowly dose up until you find you dose
- tropanes accumulate in the body and is toxic, do NOT use everyday for more than a few days and make long break to detoxify.
Be safe, and a last advice if you consider working with this plant, as for salvia divinorum and most entheogens, it is a really rewarding to grow them from seeds or cuttings.
Smell like tea n,n spirit !
Toke the toke, and walk the walk !