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Phenethylamines and Syrian Rue Options
 
ComaProphet
#1 Posted : 2/9/2009 7:06:23 PM

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I have heard reports of how dangerous this combination can be... but I have yet to learn WHY this is the general understanding.

Can anyone provide information on the actual risk of combining these two?

Thanks.Smile
Meditation to cure Depression.

What It Will Do for You

This meditation totally recharges you.
It is an antidote to depression. It builds a new system, gives you the capacity and caliber to deal with life, and gives you a direct relationship with your pranic body.
How to Do It
Sit with a straight spine in easy pose. Arms are extended straight out in front of you, parallel to the ground. Close your right hand into a fist. Wrap your left fingers around it. The bases of the palms touch. The thumbs are close together and are pulled straight up. The eyes are focused on the thumbs.
Now inhale for 5 seconds (do not hold the breath in); exhale for 5 seconds; hold the breath out for 15 seconds. Continue.
Start with 3 - 5 minutes and work up to 11 minutes. Build up the time slowly.
In time, you can work up to holding the breath out for 1 full minute.
 

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Jorkest
#2 Posted : 2/9/2009 7:23:20 PM

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SWIM has actually used low doses of maoi's with phen's..and he says it is NOT that nice...it speeds you up way too much..its like your body doesnt know what to do with all the energy..your heart rate may increase...and so will your temperature..it doesnt feel good..it feels dangerous..i think they call it a hypertensive crisis..

IT IS EXTREMELY DANGEROUS TO MIX...DO NOT DO IT EVER...

SWIM was risking his life by even trying low doses..dont do it
it's a sound
 
69ron
#3 Posted : 2/9/2009 8:13:50 PM

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The achuma cactus is said to contain MAOIs which potentiate the mescaline, making them much more potent. Achuma is not known to be dangerous.
You may remember me as 69Ron. I was suspended years ago for selling bunk products under false pretenses. I try to sneak back from time to time under different names, but unfortunately, the moderators of the DMT-Nexus are infinitely smarter than I am.

If you see me at the waterpark, please say hello. I'll be the delusional 50 something in the American flag Speedo, oiling up his monster guns while responding to imaginary requests for selfies from invisible teenage girls.
 
ComaProphet
#4 Posted : 2/9/2009 8:25:47 PM

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Jorkest wrote:
SWIM has actually used low doses of maoi's with phen's..and he says it is NOT that nice...it speeds you up way too much..its like your body doesnt know what to do with all the energy..your heart rate may increase...and so will your temperature..it doesnt feel good..it feels dangerous..i think they call it a hypertensive crisis..

IT IS EXTREMELY DANGEROUS TO MIX...DO NOT DO IT EVER...

SWIM was risking his life by even trying low doses..dont do it


Thanks for the heads up.

SWIM has some 2c-i to experiment with and he thanks you for letting him know how SWIY's experience was with that particular combination.

Does anyone know what would be a better choice to mix with phen's, like anything that helps intensify the effects in a safe and comfortable way?

And also, I know that most mesc. containing cacti are NOT safe to mix with MAOI's because of the myriad of other chems that are contained within them.
Meditation to cure Depression.

What It Will Do for You

This meditation totally recharges you.
It is an antidote to depression. It builds a new system, gives you the capacity and caliber to deal with life, and gives you a direct relationship with your pranic body.
How to Do It
Sit with a straight spine in easy pose. Arms are extended straight out in front of you, parallel to the ground. Close your right hand into a fist. Wrap your left fingers around it. The bases of the palms touch. The thumbs are close together and are pulled straight up. The eyes are focused on the thumbs.
Now inhale for 5 seconds (do not hold the breath in); exhale for 5 seconds; hold the breath out for 15 seconds. Continue.
Start with 3 - 5 minutes and work up to 11 minutes. Build up the time slowly.
In time, you can work up to holding the breath out for 1 full minute.
 
Jorkest
#5 Posted : 2/9/2009 9:49:28 PM

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small doses of DMT are nice with phens...and weed is decent..lsd too
it's a sound
 
psychonaut
#6 Posted : 2/9/2009 10:01:00 PM
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Jorkest wrote:
small doses of DMT are nice with phens...and weed is decent..lsd too

LSD is great with most phens Smile

To intensify it, you could try taking L-Tyrosine and 5HTP. They do increase it a little bit but do a lot to extend it and help with comedowns(if there are any, like some types of substituted phens have).

Controversially, piracetam(taken in an attack dose the day of) has been said to potentiate MDMA and many other phens/psys quite nicely. Could always consider that
 
DarkShaman
#7 Posted : 2/9/2009 10:04:27 PM

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I'm a bit confused as to the whole ssri-->maoi-->phen combination danger concept. The reason behind this is that I take zoloft (an ssri) and an above-average doseage of adderall (which, I don't think is a phen, but is an amphetamine all the same) on a daily basis. Additionally, I have combined harmaline, alcohol, and various other things with dmt and can't say that I've ever experienced any ill effects. Any thoughts?
 
psychonaut
#8 Posted : 2/9/2009 10:09:25 PM
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DarkShaman wrote:
I'm a bit confused as to the whole ssri-->maoi-->phen combination danger concept. The reason behind this is that I take zoloft (an ssri) and an above-average doseage of adderall (which, I don't think is a phen, but is an amphetamine all the same) on a daily basis. Additionally, I have combined harmaline, alcohol, and various other things with dmt and can't say that I've ever experienced any ill effects. Any thoughts?


amphetamine is considered a phen. MAOI + SSRI is dangerous because it causes too much serotonin to be in the brain and possible serotonin syndrome(SSRIs stop serotonin from being taken back into the synapse and MAOIs stop MAO from metabolizing serotonin). Phen + MAOI is dangerous because phens are generally heavy on dopamine and noradrenaline. If there is less MAO, then there is more of both and they then have more of an effect(increase heart rate, blood pressure, temperature, etc.)
 
Observant
#9 Posted : 2/9/2009 10:46:49 PM

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ComaProphet wrote:


Does anyone know what would be a better choice to mix with phen's, like anything that helps intensify the effects in a safe and comfortable way




Hi Coma Prophet ,


I think maybe you could intensify your mescaline with Piperine , or cacao /cacao extracts , or even Piracetam?

What about Cannabis or Nitrous Oxide ?
Had he more quickly realized just who they were,he would have shown them more respect.Had he tried harder to fathom their brilliant minds,he would have taken more of their teachings to heart.Had he more clearly understood the purpose of their being,
he would have more vigorously tried to assist them.They were truly honorable; he was sadly prejudiced.
They were exceedingly well informed; he was grossly ignorant.They were totally indefatigable; he so often, and so quickly,gave up. Still, for many years there was a strong inter-species alliance between the Eleven-Eleven of the Half-way Realm, their Seraphic Associates,and their flesh-and-blood friend, a common mortal. Much was accomplished, many profited, and, there’s only one regret...They could have achieved so much more...

All Hypnotizing Hypnotizes Hypnotizing
 
Observant
#10 Posted : 2/10/2009 12:11:59 PM

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Just found some more Infos in the Visionary cactus Guide :

Quote:
COMBINATIONS OF MESCALINE AND OTHER SUBSTANCES

Mescaline can be successfully potentiated by several other substances, a few of which will be listed below. Part of the reason why a peyote trip is different from a San Pedro trip, or one with synthetic mescaline is the mix of other alkaloids. Peyote and other cacti sometimes contain significant amounts of quinolines or other compounds that are known to potentiate mescaline, or at least affect the trip. The subjective effects of ingesting mescaline can be varied widely depending on set and setting and other compounds ingested concurrently.

LSD - When mescaline and LSD are used in combination, the recommended dosage is: 200 - 400 mg of mescaline with 100 - 300ug of LSD. This combination has been described as smoother, more mellow, and giving a longer experience than each used alone. Some subjects find this to be a rather trying trip, considering it as harsh with unpleasant somatic effects.

There have been a significant number of studies in this area in the mid to late 1950's. After giving a high dose mixture of mescaline and LSD to 74 chronic neurotics in the early 1960's, some surprising results were discovered. After 6 months, 12 subjects showed marked improvement, 22 showed some improvement, and the rest showed slight improvement.



Licorice Root - There is evidence that mescaline can be potentiated by drinking a tea made from licorice root (Glycyrrhiza glabra). 2 to 3 cups of strong tea are brewed and consumed at the start of or at the waning stages of the trip. It is said to increase the intensity of the experience by up to 3 times. This tea may contain MAOI's, so caution is advised.

Melatonin - I have heard a report that Melatonin ( available in most Health food stores ) will potentiate the effects of ingesting mescaline. The preferred and most effective method is to take 10-15mg before bed, a week in succession before the trip. If this is not practical, 20-25mg may be taken at least 12 hours before the actual trip. The later method works but is not as efficient as the week long method. It is said that the "7 day boost" used in conjunction with beta-carbolines (below) results in an "ultra-euphoric boost".

Beta carbolines - Several people reported to me that they had potentiated mescaline with Harmala compounds such as Syrian rue (Peganum harmala). The average amount ingested was around 3-5 grams of powdered or extracted seeds. Powdered seeds can be put into gel-caps to hide the intense bitterness. It is said that this method can increase the intensity of the trip 3 fold, and up to double the duration. It is said that frequent use of this combination will bring about a marked tolerance. Exercise caution as harmala compounds are MAOI's. The preferred method of ingesting Syrian rue is the water extraction technique.



Ginger Tea - I have also heard reports that a strong tea made of ginger would potentiate the effects of mescaline. No further details available.

Solanaceus Herbs - Peruvian curanderos have been known to add Datura (a solanaceous plant) to the boiled San Pedro extract to give it stronger powers of divination. Contains atropine, scopolamine and other tropanes. Use these substances with extreme caution.

Moclobomide - There have been recent reports that this substance will markedly increase the intensity and duration of the trip.


Had he more quickly realized just who they were,he would have shown them more respect.Had he tried harder to fathom their brilliant minds,he would have taken more of their teachings to heart.Had he more clearly understood the purpose of their being,
he would have more vigorously tried to assist them.They were truly honorable; he was sadly prejudiced.
They were exceedingly well informed; he was grossly ignorant.They were totally indefatigable; he so often, and so quickly,gave up. Still, for many years there was a strong inter-species alliance between the Eleven-Eleven of the Half-way Realm, their Seraphic Associates,and their flesh-and-blood friend, a common mortal. Much was accomplished, many profited, and, there’s only one regret...They could have achieved so much more...

All Hypnotizing Hypnotizes Hypnotizing
 
acolon_5
#11 Posted : 2/10/2009 2:41:48 PM

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associativum wrote:
ComaProphet wrote:


Does anyone know what would be a better choice to mix with phen's, like anything that helps intensify the effects in a safe and comfortable way




Hi Coma Prophet ,


I think maybe you could intensify your mescaline with Piperine , or cacao /cacao extracts , or even Piracetam?

What about Cannabis or Nitrous Oxide ?


I can personally tell you that piracetam @ 1-2g/day for a week or two prior to taking mescaline, 2C-X, or MDxx will change, potentiate, and extend the experience. Melatonin also works well in combination with Mescaline to potentiate the experience (can't tell you why, just that it works).

MAOI's + San Pedro and Achuma have been tested and found to increase potency and duration without dangerous or uncomfortable side effects. I would not ever mix with 2C-x.

A mix of piracetam daily + 4-6mgs of melatonin nightly + 1.5grams syrian rue extracted into a tea combined with 40g alcohol extracted Achuma (each) resulted in a 14hr extremely euphoric and visual experience for both the wife and I.
The Spice extends life
The Spice expands consciousness
The Spice is vital for space travel
___________________________________________________________________________________________________
Never underestimate the power of STUFF!


I am certifiably insane, as such all posts written by me should be regarded as utter nonsense or attempts to get attention.

I don't know SWIM and personally don't trust him at all. If SWIM is posting, most likely I will not respond...as I said, I don't trust the guy. YOU I trust, but never SWIM.
 
Observant
#12 Posted : 2/10/2009 3:42:01 PM

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Another Thread with highly useful Information Smile
Thanks acolon !

Had he more quickly realized just who they were,he would have shown them more respect.Had he tried harder to fathom their brilliant minds,he would have taken more of their teachings to heart.Had he more clearly understood the purpose of their being,
he would have more vigorously tried to assist them.They were truly honorable; he was sadly prejudiced.
They were exceedingly well informed; he was grossly ignorant.They were totally indefatigable; he so often, and so quickly,gave up. Still, for many years there was a strong inter-species alliance between the Eleven-Eleven of the Half-way Realm, their Seraphic Associates,and their flesh-and-blood friend, a common mortal. Much was accomplished, many profited, and, there’s only one regret...They could have achieved so much more...

All Hypnotizing Hypnotizes Hypnotizing
 
DarkShaman
#13 Posted : 2/10/2009 5:46:33 PM

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psychonaut wrote:
DarkShaman wrote:
I'm a bit confused as to the whole ssri-->maoi-->phen combination danger concept. The reason behind this is that I take zoloft (an ssri) and an above-average doseage of adderall (which, I don't think is a phen, but is an amphetamine all the same) on a daily basis. Additionally, I have combined harmaline, alcohol, and various other things with dmt and can't say that I've ever experienced any ill effects. Any thoughts?


amphetamine is considered a phen. MAOI + SSRI is dangerous because it causes too much serotonin to be in the brain and possible serotonin syndrome(SSRIs stop serotonin from being taken back into the synapse and MAOIs stop MAO from metabolizing serotonin). Phen + MAOI is dangerous because phens are generally heavy on dopamine and noradrenaline. If there is less MAO, then there is more of both and they then have more of an effect(increase heart rate, blood pressure, temperature, etc.)


So then it sounds as if a combination of all three should be considered quite dangerous, no? Perhaps this explains the frequent migraines that I've been experiencing, and maybe even my high blood-pressure. . . Damn pharmeceutical companies!
 
Jorkest
#14 Posted : 2/10/2009 5:56:02 PM

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that would do it..you may want to try not taking those drugs..and see if the migraines go away
it's a sound
 
ComaProphet
#15 Posted : 2/10/2009 6:13:47 PM

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Thanks to you all for the awesome response to this thread, lots of useful information!

Cool
Meditation to cure Depression.

What It Will Do for You

This meditation totally recharges you.
It is an antidote to depression. It builds a new system, gives you the capacity and caliber to deal with life, and gives you a direct relationship with your pranic body.
How to Do It
Sit with a straight spine in easy pose. Arms are extended straight out in front of you, parallel to the ground. Close your right hand into a fist. Wrap your left fingers around it. The bases of the palms touch. The thumbs are close together and are pulled straight up. The eyes are focused on the thumbs.
Now inhale for 5 seconds (do not hold the breath in); exhale for 5 seconds; hold the breath out for 15 seconds. Continue.
Start with 3 - 5 minutes and work up to 11 minutes. Build up the time slowly.
In time, you can work up to holding the breath out for 1 full minute.
 
DarkShaman
#16 Posted : 2/10/2009 9:18:53 PM

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Jorkest wrote:
that would do it..you may want to try not taking those drugs..and see if the migraines go away


Word. I've been looking for a reason to stop taking that crap anyways.
 
psychonaut
#17 Posted : 2/11/2009 1:03:35 AM
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DarkShaman wrote:
Jorkest wrote:
that would do it..you may want to try not taking those drugs..and see if the migraines go away


Word. I've been looking for a reason to stop taking that crap anyways.


take some LSD for migraines!
If cessation does stop the migraines, you might want to consider dropping one of them or at least skipping your dose when using an MAOI. Sounds like a good plan Smile
 
DarkShaman
#18 Posted : 2/11/2009 3:24:59 AM

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I would love to take some lsd - that is, if real lsd were even available these days.
Oh well, at least I have nothing to fear from the dark, psilocybic lair in which I dwell.



p.s.-free mumia
 
69ron
#19 Posted : 2/11/2009 5:12:33 AM

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Small amounts of LSA are also great for headaches, as are small amount of 5-MeO-DMT. A good source of 5-MeO-DMT is virola resin. About 500 mg of the resin taken orally is enough to use for most headaches without it being hallucinogenic. The advantage 5-MeO-DMT has over LSD or LSA is that it doesn’t keep you up all night because it only lasts a couple of hours.
You may remember me as 69Ron. I was suspended years ago for selling bunk products under false pretenses. I try to sneak back from time to time under different names, but unfortunately, the moderators of the DMT-Nexus are infinitely smarter than I am.

If you see me at the waterpark, please say hello. I'll be the delusional 50 something in the American flag Speedo, oiling up his monster guns while responding to imaginary requests for selfies from invisible teenage girls.
 
psychonaut
#20 Posted : 2/11/2009 9:46:43 PM
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69ron wrote:
Small amounts of LSA are also great for headaches, as are small amount of 5-MeO-DMT. A good source of 5-MeO-DMT is virola resin. About 500 mg of the resin taken orally is enough to use for most headaches without it being hallucinogenic. The advantage 5-MeO-DMT has over LSD or LSA is that it doesn’t keep you up all night because it only lasts a couple of hours.


dosage for migranes would be sub psychadelic in any case(for lsd, 10ug or so apparently works, even for longer periods of time after taking it). problem would be making sure it is actually LSD(it is defiantly around though). 5-MeO-DMT would probably be really effective. .5 mg sublingual? a decent amount would last you for life for treating migraines.
 
 
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