I have been a member for a while.

There are some aspects of DMT usage that I'd like to discuss within an open forum, ranging from pineal gland research (such as possible piezoluminescence, piezochromism of calcite crystals), extraction modifications to current procedure, and experimentation with IV drip fumarate.

Also, I'm very interested in transdermal experimentation utilizing DMSO, though I have found many conflicting reports about this.

Lastly, I'd like to share additives used in ayahuasca preparation (ranging from traditional scopolamine containing additives to the strange and exotic).

Apis mellifera

When you say transdermal, do you mean like a dermal gel or patch of some sort?

This is something I've always been curious about, since it would offer a way around the need for MAOIs, and could potentially be engineered for a trip of any length of time.

I believe it was House who posted mention of spilling a DMT rich solution on his arms during an extraction procedure, and tripping hard for a couple hours. So we know that in principle it could work.

Hello,

I have some experience with using 5-meo-dipt in DMSO as a massage oil, it was subtle, but noticeable. Friends of mine are crazy about it.

Well a transdermal patch would be some type of gel (like fentanyl patches) but I honestly hadn't even thought of that.

One key aspect of transdermal success would be applying the DMSO/DMT(acid salt) solution to an area that is high in blood flow, such as the radial artery. Because of the thin skin and the rushing river of blood, I don't see why it wouldn't work.

After efforts had been made to establish the viability of transfer, you could narrow the range of effective dose, starting like Strassman and working up to 0.4mg/kg.

One reason this method failed in the past is because it was attempted by smearing the solution on the chest. Though the solution will go into many blood vessels here, it lacks a major arterial pathway that is not protected by, say the ribcage (a la aorta).

@Guyomech: I believe this ROA would be similar to IV injection, with a much softer, more subtle and elaborate come up but similar duration. Think about the DMT entering the bloodstream, it's coming through the skin (indirectly) instead of being forced into the vein.

I have an interest in exploring an extended intravenous injection that continuously drips DMT into a subject at the metabolic rate of consumption, thus keeping the DMT in their blood at a certain level. The idea for this would be to extend the "hyperspace" time, or the time the subject's ego was completely dissolved to better understand the effects. However, I don't know if your body could maintain that state without failing.