Here is his TEK: https://www.dmt-nexus.me...aspx?g=posts&t=18083

He uses toluene as the solvent and does an A/B extraction. Anyone have any ideas to improve the tek to it yields a better product? I was thinking of using a solvent instead of toluene such as naphtha or heptane but i am not sure if they would work.

Any ideas?

Here is his TEK: https://www.dmt-nexus.me...spx?g=posts&t=18083

He uses toluene as the solvent and does an A/B extraction. Anyone have any ideas to improve the tek to it yields a better product? I was thinking of using a solvent instead of toluene such as naphtha or heptane but i am not sure if they would work.

Any ideas?

i think a drytek using pickling lime and d-limonene would give a more complete blend of actives and be a better end product. I may try that actually, ive got all the materials here already.

i always just toss and wash since extracts never satisfied me, but it would nice to have a crystal concentrate for smoking.

i've often wondered about a smoking extract.. from what i've heard is that it's not very efficient... prolly be better off with a poppy pod extract for smoking..

i don't know how you toss and wash,, i'd puke it up asap. lol... generally i just stick it in a half filled bottle of water, shake it up, hold my nose and guzzle, then eat some crackers while holding my nose and prolly drink some juice.. lol..

i've bought a few extracts, and they were effective, but i'm not sure of the tek used, and even then i would just mix the extract with some regular powder just to make it a little more magical..

also, i've noticed, in tinctures that you lose a lot of the alkaloids.. there just seems to be something about taking in the whole grinded up powdered for the best bang

def let us know what u discover, interested to hear

curious as to how you came to this conclusion..was is just from the experience?

with most extracts, the key is full homogenization (lysis) of plant cells, because alkaloids
are produced in vivo within plant cell walls. after a plant has been processed in this manner, any number of extraction techniques may be employed, including, but not limited to, soxhlet extraction, SPE columns, and the familiar A/B. I'd opt for the soxhlet, or better yet, UAE (ultrasound-assisted extraction) using 95% ethanol.

yeah it was from the experience.. i've tried various tinctures from different "strands" and each one felt weak over ingesting the plant material itself.. it's possible the extraction method is off for sure... i've never actually made my own tincture but the ones i have drank i believe ethanol was used, but i'm not sure... a chemist friend makes them.. it just seems that there was a loss in potency and i would have to consume more tincture compared to how much plant material was needed for ingestion, at the ratio of alkaloids in tincture compared to just plant material, i.e. ingesting the plant material is more bang for my buck. but like i said, that's just my experience

it could be strain variation, or incomplete lysis. again, the latter is critical in any extraction, I can't stress it enough. Makes perfect sense in theory, and in practice. having employed a pressure cooker or ultrasonic cell disruptor, the difference is night and day, as opposed to just using a blender or coffee grinder.

I have heard that kratom alkaloids are subject to heat degradation, hence a heated extraction would lose some potency..

really?

in that case, several freeze cycles in alcohol may do the trick, or, as I mentioned, UAE
(put the container with alcohol and plant material in an ice bath if using UAE). I've done this with an alcoholic extraction of psilocybin from dried fungal biomass, very effective.

You are right, my friend. The solubility of Mitragynine/7-hydroxo in water is extremely low. In ethanol, it is only 5mg/ml and in methanol it is 10mg/ml. Therefore, tinctures are not effective due to poor solubility in ethanol. If one looks to make a tincture, you must search for alternative solvents (that are food safe of course) to dissolve the alkaloids.

Anyone know if DMSO could be the effective carrier?

with seven H-bond acceptors, I find that hard to believe that 7-hydroxymitragynine has difficult solubility in short-chained aliphatic alcohols. some people make extracts and tinctures from kratom like they do with s. divinorum..with a soxhlet and an alcohol.