The only psychedelics I've experienced are lsd and psilocybin. I know it sounds cliche, but LSD really did change my life. I went from pretty much not caring about life with little interest in anything to sort of questioning reality and wanting to know everything about everything.
Right now I'm about to finish organic chemistry I and will be taking II over the summer, so I don't have too much chemistry experience (but I'm getting there
). I'm still somewhat undecided, but as of now I actually intend to focus on physical chemistry in the future.
I've actually never even heard of ayahuasca, but... perhaps that is something I might consider looking into.