Pinoline, and other tryptoline derivatives (beta carbolines), etc, are all very structurally close to harmalas, and produced in the body.
DMT, 5-ho-dmt, have both been detected in urine from man. They are also very close structurally to setotonin, melatonin, and other tryptamine based neurotrasmitters in the body.
they're (tryptamines, beta carbolines) all over the natural world, plants, animals, fungus, etc. Almost all life have derivatives of those basic structures in some form. Many times overlapping between species.
In man non-typical tryptamines, and tryptolines are present, but the only evidence for that shows not in significant amounts (trace amines, lots of exotic structures floating around in our bodys).
That is to say, at the time of observation, they were not detected in amounts that would be considered to have a physiological affect. Not to say they could in other circumstances, perhaps it was just at the time of observation they were low, i'm just speculating there though. or perhaps in some way contribute to mental illness in those who have abnormally high levels of exotic trace amines. Those last parts are pure speculation though.
The only thing known about endogenous "harmalas & dmt", is that they are present, in low amounts. In the case of harmalas, not even the same structure, but closely related and possible that they have some kind of trace amounts of tryptolines in common with other species, but have not been detected as of yet.
anything beyond the fact that they're there, but in low concentrations and alongside other exotic amines that get dominated by serotonin and the other major neurotransmitters, is speculation. They could (and prob do imho) have some role in neurochemistry, but perhaps they're just evolutionary byproducts pushed aside by evolutionary forces that favored other structures. In that case they play no significant role, but its just a random guess, as theres no scientific data to back up those speculations.
"let those who have talked to the elves, find each other and band together" -TMK
In a society in which nearly everybody is dominated by somebody else's mind or by a disembodied mind, it becomes increasingly difficult to learn the truth about the activities of governments and corporations, about the quality or value of products, or about the health of one's own place and economy.
In such a society, also, our private economies will depend less upon the private ownership of real, usable property, and more upon property that is institutional and abstract, beyond individual control, such as money, insurance policies, certificates of deposit, stocks, etc. And as our private economies become more abstract, the mutual, free helps and pleasures of family and community life will be supplanted by a kind of displaced citizenship and by commerce with impersonal and self-interested suppliers...
The great enemy of freedom is the alignment of political power with wealth. This alignment destroys the commonwealth - that is, the natural wealth of localities and the local economies of household, neighborhood, and community - and so destroys democracy, of which the commonwealth is the foundation and practical means.” - Wendell Berry