Is it Greedy to want to see everyone's Smile ?
Posts: 389 Joined: 03-Apr-2012 Last visit: 15-Jan-2015
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i have not read the 'spirit molecule' book yet have had a look at it, it is very large i am looking to purchase it soon i have the dvd. i was wandering does any one know what type of DMT is released from the Pineal gland? also do they know, is the Pineal gland always active a little? and is it fact that the Pineal gland is active at 48-49 days conception? cheers, plrrrrrr. "Given enough Time even Hydrogen starts to wonder where it came from, and where it is going"
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analytical chemist
   
Posts: 7463 Joined: 21-May-2008 Last visit: 14-Jan-2025 Location: the lab
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ACS-grade DMT is released from the pineal, along with PCP. when you die, your brain pumps out heavy doses of MDMA. Babies have extraordinary levels of datura in their peanut-sized brains. "Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
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bird-brain
Posts: 959 Joined: 26-Apr-2010 Last visit: 30-Oct-2020
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I don't believe any DMT is released from the pineal gland. blooooooOOOOOooP fzzzzzzhm KAPOW!
This is shit-brained, this kind of thinking.
Grow a plant or something and meditate on that
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Posts: 6739 Joined: 13-Apr-2009 Last visit: 10-Apr-2022
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DMT-Nexus member
Posts: 473 Joined: 07-Aug-2011 Last visit: 10-Jan-2014
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Hello new dmt-nexus friend  . The FAQ has a lot of good information. https://wiki.dmt-nexus.me/FAQ
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DMT-Nexus member
Posts: 3207 Joined: 19-Jul-2011 Last visit: 02-Jan-2023
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benzyme wrote:ACS-grade DMT is released from the pineal  is this sarcasm or can i get a link? My wind instrument is the bong
CHANGA IN THE BONGA!
樹
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Posts: 6739 Joined: 13-Apr-2009 Last visit: 10-Apr-2022
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^You forgot to quote the PCP part.
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DMT-Nexus member
Posts: 42 Joined: 31-Mar-2012 Last visit: 21-Apr-2012 Location: Virginia
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According to Strassman in 'The Spirit Molecule' as well as in his chapters within the book 'Inner Pathways to Outer Space' there has been no definitive evidence that the pineal gland is the source of endogenous dmt. There has been no studies or experiments that have been able to prove it one way or another. At present, there is only speculation. "I have no special talents, I'm only passionately curious." -Albert Einstein
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DMT-Nexus member
Posts: 388 Joined: 25-Aug-2011 Last visit: 14-Sep-2020 Location: temporarily on the move
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The Spirit Molecule is a very fascinating piece. It's definitely worth getting it, I've finished it in 4 days I think, it's that interesting. Lots of new information (to me), and lots of extra knowledge I found so useful for my own personal journeys. 3toedsloth wrote:There has been no studies or experiments that have been able to prove it one way or another. At present, there is only speculation. ...however, research is always welcome in finding out more about the inner workings of DMT. Personally, I find this pineal theory pretty logical (from a layman's POV), although not even close to being complete. The development of the pineal in human beings, as well as the role of the pineal in the human body, fascinated me over the head. Precisely this: The Spirit Molecule wrote:The pineal gland is unique in its solitary status within the brain. All other brain sites are paired, meaning that they have left and right counterparts; for example, there are left and right frontal lobes and left and right temporal lobes. As the only unpaired organ deep within the brain, the pineal gland remained an anatomical curiosity for nearly two thousand years. No one in the West had any idea what its function was.
[...]
The human pineal gland becomes visible in the developing fetus at seven weeks, or forty-nine days, after conception. Of great interest to me was finding out that this is nearly exactly the moment in which one can clearly see the first indication of male or female gender. Before this time, the sex of the fetus is indeterminate, or unknown. Thus, the pineal gland and the most important differentiation of humanity, male and female gender, appear at the same time.
The human pineal gland is not actually part of the brain. Rather, it develops from specialized tissues in the roof of the fetal mouth. From there it migrates to the center of the brain, where it seems to have the best seat in the house. The truth...lies within.
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Kalt und Heiß, Schwarz und Rot, Kürper und Geist, Liebe und Chaos
Posts: 4661 Joined: 02-Jun-2008 Last visit: 30-Apr-2022
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rjb wrote: Personally, I find this pineal theory pretty logical (from a layman's POV), although not even close to being complete. The development of the pineal in human beings, as well as the role of the pineal in the human body, fascinated me over the head. Precisely this: The Spirit Molecule wrote:The pineal gland is unique in its solitary status within the brain. All other brain sites are paired, meaning that they have left and right counterparts; for example, there are left and right frontal lobes and left and right temporal lobes. As the only unpaired organ deep within the brain, the pineal gland remained an anatomical curiosity for nearly two thousand years. No one in the West had any idea what its function was.
[...]
The human pineal gland becomes visible in the developing fetus at seven weeks, or forty-nine days, after conception. Of great interest to me was finding out that this is nearly exactly the moment in which one can clearly see the first indication of male or female gender. Before this time, the sex of the fetus is indeterminate, or unknown. Thus, the pineal gland and the most important differentiation of humanity, male and female gender, appear at the same time.
The human pineal gland is not actually part of the brain. Rather, it develops from specialized tissues in the roof of the fetal mouth. From there it migrates to the center of the brain, where it seems to have the best seat in the house. Logical or not, unless demonstrated, these claims are only hypotheses and speculations and not much more. FWI, Strassman really stacked the cards to his advantage when "selling" this idea. Be wary of this, since he lets you know only what it supports the pineal notion. And besides, it's a layman's book not a scientific publication (where such attitude would be criticised and corrected). Need to calculate between salts and freebases? Click here! Need to calculate freebase or salt percentage at a given pH? Click here!
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DMT-Nexus member
Posts: 126 Joined: 09-Sep-2011 Last visit: 08-Dec-2019 Location: Romania
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Pineal Gland or not there IS DMT in the human body
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DMT-Nexus member
Posts: 14191 Joined: 19-Feb-2008 Last visit: 06-Feb-2025 Location: Jungle
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Yes, and 5-meo-dmt and bufotenine and a bunch of other molecules
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DMT-Nexus member
Posts: 201 Joined: 10-Apr-2011 Last visit: 07-May-2024
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There is no direct evidence that states the pineal gland stores or excretes DMT. Im not sure if its still there but you tube had the video documentary for the spirit molecule, it was broken into about 4-5, 20min sections, but summed up the book pretty well. I read the book too and of course that's the better way to go. "..I find myself stirred awake by the ambient noises of the world outside and a realization that my train of thought may not be running on time…but I've nowhere to be...except here."
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DMT-Nexus member
Posts: 42 Joined: 31-Mar-2012 Last visit: 21-Apr-2012 Location: Virginia
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Quote:...however, research is always welcome in finding out more about the inner workings of DMT. Personally, I find this pineal theory pretty logical (from a layman's POV), although not even close to being complete. Until the theory IS complete and is demonstrated and proven, I look at it like any other hypothesis. It does SEEM probable, but then again there's a WHOLE LOT we don't quite understand about the human brain, so what seems logical doesn't necessarily mean it's the truth. Quote:Pineal Gland or not there IS DMT in the human body They've had a great difficulty proving this too! What they know is that the chemical compounds that MAKE UP dmt exists in the body. But that's like saying u have a tank with hydrogen and oxygen in it, so you must have water. Not necessarily true. Whenever a scientific publication is written, reviewed, scrutinized, and accepted that shows this to be the case, I'll be as excited as everyone else about it! "I have no special talents, I'm only passionately curious." -Albert Einstein
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analytical chemist
Posts: 7463 Joined: 21-May-2008 Last visit: 14-Jan-2025 Location: the lab
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There was an abstract poster for a new study regarding the matter, but the authors were unable to show the DNA which codes for INMT in pineal gland cells. fail. attached is the widely-cited study on human INMT isolation and expression in vitro. "Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
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DMT-Nexus member
Posts: 42 Joined: 31-Mar-2012 Last visit: 21-Apr-2012 Location: Virginia
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Quote:attached is the widely-cited study on human INMT isolation and expression in vitro. sorry, can't open the attachment at work. can u summarize? "I have no special talents, I'm only passionately curious." -Albert Einstein
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analytical chemist
Posts: 7463 Joined: 21-May-2008 Last visit: 14-Jan-2025 Location: the lab
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western and northern blot analysis shows bands corresponding to INMT isolated from various peripheral tissues in humans, matched up with positive controls from rabbit cells. there were none seen in human brain cells. "Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
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DMT-Nexus member
Posts: 42 Joined: 31-Mar-2012 Last visit: 21-Apr-2012 Location: Virginia
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Quote:western and northern blot analysis shows bands corresponding to INMT isolated from various peripheral tissues in humans so this supports what i said earlier that the 'ingredients' are there, but they have yet to find actual DMT? forgive me for being a layman on the subject. "I have no special talents, I'm only passionately curious." -Albert Einstein
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analytical chemist
Posts: 7463 Joined: 21-May-2008 Last visit: 14-Jan-2025 Location: the lab
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correct. the KEGG pathway shows a direct path from tryptophan to NMT, in two steps: decarboxylation from AADC (aromatic amino-acid decarboxylase, EC# 4.1.1.28 ), and N-methylation from INMT (indoleethylamine-n-methyltransferase, EC# 2.1.1.49, using S-adenosyl methionine as a co-substrate). It's likely the latter step occurs twice, to give DMT, but this has not been shown in-vivo, because MAO in epithelial cells mark it (oxidation) for degradation. the KEGG pathway for tryptophan metabolism shows parallel pathways for serotonin--> melatonin, and acetyl-melatonin, thus production of these products inactivates production of NMT and DMT, and vice-versa. We've evolved a metabolic tendency to favor the former products. finally, the proteins which would produce DMT are concentrated in peripheral tissue cells, i.e. the lungs, adrenals, heart, and muscle tissues. "Nothing is true, everything is permitted." ~ hassan i sabbah
"Experiments are the only means of attaining knowledge at our disposal. The rest is poetry, imagination." -Max Planck
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DMT-Nexus member
Posts: 42 Joined: 31-Mar-2012 Last visit: 21-Apr-2012 Location: Virginia
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Quote:so in conclusion, the proteins which would produce DMT are concentrated in peripheral tissue cells, i.e. the lungs, adrenals, heart, and muscle tissues. forums really are an amazing thing! thank you for breaking it down for the rest of us. it's wonderful to know that there are people from all walks of life (including high intellects such as yourself) interested in these topics and posting here on these boards! It definitely allows for multiple perspectives which is for the better of all our understanding "I have no special talents, I'm only passionately curious." -Albert Einstein
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