Will ingesting DMT harm my brain in any way shape or form
on a count of I am taking 50 mg of 5-htp a day?

no.

no it will not. I take 2 500mg L-tryptophan everyday. Tryptophan synthesizes in your body into DMT, 5-HTP, serotonin (5-HT), melatonin, and also niacin. They are both neurotransmitters. Smoking DMT does not increase the amount of serotonin in your body, nor does it decrease it.

I don't know about that, but I take 5-htp and l-tryptophan every day, and use aya and or vaprorized spice with oral/smoked harmalas every week with no problems.

no, but it will compete with 5HT for active binding sites.

either is good to take for jet lag, or disrupted sleep patterns. I prefer l-tryptophan

5-HTP won't really potentiate anything, because it's a precursor for 5HT, and 5HT competes with other ligands for active binding sites on the serotonin receptors. if it were a noncompetitive allosteric affector, it might be a different story

yea, it's called aniracetam.

oh yeah.

I did take 5-htp for awhile but switched to tryptophan. My body will regulate what it needs from that. 5-htp only goes one direction. Tryptophan has many uses.

I find that it def regulates my mood a bit. I find it has a calming effect due to the serotonin. My sleep seems restful. Vit b6 is important to take as it is needed for 5-ht synthesis. I also take alpha brain. And a high dose of vit d3. The alpha brain has a ton of stuff in it. Makes things a little more sharp.

Interesting stuff don't know how I missed it. Anything you can tell me about aniracetam that I won't read anywhere? And what do you mean by it being a potentiator for dmt? (edit: nm I understand this last part)

I feel retarded posting around you benzyme. lol

I'm really interested how those works in association now.
Now I used L-dopa and 5HTP both from plant source (Mucuna pruriens, and griffonia extracts) in the morning, and melatonin in night.
It seems to work well together, boosting dreamwork and mood.

But Benzyme, you'd say they don't synergize but rather compete each others ?

I take 5-htp and tryptophan both to decrease "aggression" and increase general "calmness" over the course of the day.

There is a bit of research out there re: testosterone, serotonin and aggression. For me it's been an emotional lifesaver.

Will have to check out aniracetam though.

benzyme, you are saying using l-tryptophan next to maoi's (reversebles) from rue or caapi is safe ?

rOm, I had one experience with Mucuna pruriens extract. Right after taking it me and a friend felt it directly not only that.
It affected a aya work that night gave some pressure in the head. Also the next days session was influenced, potentiated and again with head pressure.
For me it feels like a no go,

How does it work for you ?

I never did yet next to harmalas. and I'm wary of it.

Benzyme can I ask you to elaborate on aniracetam as it relates to dmt. Would it be considered a potentiator ?

possibly

according to japanese research, it acts as a 5HT2a modulator (something like a volume knob on
your stereo), and DMT is a 5HT2a ligand (molecule which binds 5HT2a).

case 1: I vaped what should've been a threshold dose, 8 mg, and took 750 mg aniracetam...the result
was akin to a 10 min heavy acid trip, or a couple grams of panaeolus cyanescens. extremely visual

case 2: I ate 3.2 g cubensis, and got mostly a body buzz with some visuals..an hour into it, I took 800 mg aniracetam. Prior to this I was all smiles and joking with a friend, who took the same. 15 mins later, we were both stunned; on shulgin's scale, we had shot up from +.5 to +++

lol it's not even like that

and a college education won't guarantee you the vernacular either, you have to actively practice it.
there are plenty of grads who don't talk the talk.

I,m wondering if aneracetam would be contraindicated
With maoi or harmala source such as caapi specifically .
Hard to find much data on this.

I'm going to check and see if I can get aniracetam at my supplement store. Benzyme, do you have any experience with Piracetam? I read that Piracetam is a cyclic derivative of GABA, I don't fully understand what this means yet, but my alpha brain contains GABA. Would taking Piracetam or Aniracetam along side GABA have any adverse side effects? Or would I need to adjust dosage according to this?



i just realized that my alpha brain supplements contain Mucuna Pruriens. And you said this had effects with DMT? I took alpha brain the day I had my breakthrough dose. I wonder how it affected it. i should probably research a little more about these supplements if I am going to be taking them in conjuction with DMT.

This is what I take (if anyone is interested) and i feel amazing. I'm working on a few hours of sleep, which for some reason every fri sat and sun (days off) I end up waking up after only a few hours of sleep and cannot go back to sleep. Yet i feel amazing.

(per day)
(1) 1000 IU Vitamin D3
(2) 500 mg L-tryptophan
(2) Alpha Brain
Which contains per 2 pills:

Alpha GPC (L-alphaglycerylphosphorylcholine) – 120 mg
Huperzine A – 100 mcg + Huperzia Serrata - 20mg (.5% Huperzine A)
Vinpocetine — 5mg
AC-11 – 350mg
Bacopa (20% Bacosides) — 500 mg
Pterostilbene — 250 mcg
Mucuna Pruriens (50% l-Dopa) — 200mg
GABA — 300mg
Oat Straw (10:1) — 300 mg
Vitamin B6 – 15 mg