I am considering smoking plants containing harmalas as a mild antidepressant and tobacco substitute and I'm wondering if that would have any side effects I should be aware of. I know that if I want to have a pure Trip i would have to stop using the harmalas for a time before the trip but would there be any other concerns regarding psychedelics?

MAOi's aren't a suggested anti-depressant,because they can cause dependance and everyday use for a prolonged period of time can have side effects.I'd suggest visiting a doctor and getting a prescription for anti-depressants.As for tobacco,i hear cannabis can be a good substitute

The prescription ssri's are way worse than some harmalas. I vape harmalas daily and notice no side effects other than bliss. You don't want to combine harmalas with certain drugs, see the Known Drug Interaction page in the Wiki for more info on contraindications.

Check out these threads.

https://www.dmt-nexus.me...aspx?g=posts&t=23263

https://www.dmt-nexus.me...aspx?g=posts&t=25317

Harmalas can help cut down on the nicotine fits.

Extract some and infuse them to mullein.

I'd say a ratio of 250mg of harmalas per gram of mullein.

Good luck on your journeys and I hope you feel better.

<3

thank you those threads helped a lot. I'll look more into it. how long should I keep the MAOIs out of my system for before a trip? is a week good?

I read about MAO-B effect with tobacco - which may explain its addiction in part. Also Here in the mediterranean type part of California are plenty of tree tobaccos growing - N. Glauca. I have some dried right now, and seeds. It's very common, and there is a deadly stigma about the stuff, but it has not killed anyone I've shared it with, including myself. There have been side effects in one person but he's weird. I noticed somewhat of a limit with it myself where it gets too be a bit tense. The active constituent is Anabasine, and way less nicotine. Anabasine has an antagonist effect on the receptors whereas Nicotine has an Agonistic effect. In effect the Anabasine fills the receptor site and one who is addicted does not feel the need to smoke a cigarette. Unfortunately some people have been smoking since the womb making it a complex interdependancy, and others have a need to feel cool so they seem to keep doing it for some reason related to that. If you don't know what I mean read the erowid experience about it. I like the stuff a bit - the fauxbacco (fobacco) but then I don't really have the need to smoke anything to feel cool

edit: if you do smoke it - take it easy, 1 rollie, no chain smoking - that's where the death stigma comes from

I don't get what you mean by how low you should keep the MAOI's out of your system before a trip... I guess it would depend on how you intend to trip?

If you plan on ingesting some DMT, then you'd want to keep some MAOI's in your system.

You can benefit from a mushroom trip by having a little bit of harmalas in your system, just be careful. You can get a massive trip with very little product by mixing mushies and harmalas.

I've read good things about harmalas and acid.

If you are planning on tripping with some Iboga or something, I'd wait at least a couple of days to get the MAOI's out of my system but I'd rather hear from someone who is experienced with Iboga for that kind of advice I guess.

So in conclusion, it appears to me that you have a LOT of researching to do where these substances are concerned.

This quote is what makes me say that:



Harmalas are good for the soul when taken with respect and they synergize well with several different substances. Just do some more research and don't jump into anything without gaining as much knowledge as you can.

The more work you put into it now, the better your journeys will be later.

Good luck and happy reading.

Edit : This would be a good place to continue reading about interactions and whatnot..

https://wiki.dmt-nexus.m...ctions_and_their_effects