..perhaps this will increase the probability of good trips, and eliminate freakouts during intense trips ( :evil: ----> )

-Is Propranalol safe to combine with psychs?

-Has anyone experimented combining psychs with any types of Beta-blockers? If so, please elaborate upon the effects/side-effects, and the names of the psych and beta-blocker used.
there are some natural beta-blockers too, but im not sure of their effectiveness.

..any ideas..?

Have you taken Propanolol? I couldn't imagine that being very nice mixed with a psychedelic.
That said... its anyone's guess.

I'm not a pharmacologist so i cant comment on the safety.

you don't have to be a pharmacologist, pharmacist, or doctor to know about the safety of any pharmaceutical.


ravers have long used Inderal to combat body load and anxiety inherent to moderate doses of
various psychedelics, particularly the phenethylamines. just don't take with other vasodilators, or if you're susceptible to type-II diabetes.

Caution is also required with propranolol if you suffer with asthma.

no Xt, i haven't tried any beta-blockers yet. i agree that pharmaceuticals usually dont synergize well with psychs, but i thought perhaps this could be an exception; and since propranalol is synthetic it would be not practical for regular use.
thanks benzyme for letting me know about Inderal. didnt know ravers used this. i will probably experiment with this in due time when i decide to take out the time to get a prescription for it, or find someone who already has some

You'd be best to just develop your shamanistic fear threshold, do some rocking back and forth in a defence position chanting something which sounds like your the man in control.

Propanalol makes me very anxious and gives me headaches. Try valium. Don't believe the hype. I have been on a small dose of valium (2.5mg) and tripped plenty hard. I didn't notice and decreased effects. It didn't really lower anxiety though. For me at least.

*shrugs*
some people react differently to different drugs. pot makes me nauseous.

Beta Blockers can also cause severe vasoconstriction in some people. It's not something that I would experiment with mixing if you value your extremities. But I say this as somebody who has moderate Raynaud's.

Stick with Xanax.

eff xanax.
inderal works, thus i see no advantage to switching to a
benzo. the former isn't quite as habit-forming as the latter.

do you mean vasodilation? otherwise there'd be no reason to administer
them to angina patients

I think maybe the first question to ask is why you are feeling anxiety with psychedelics in the first place, and if maybe couldnt you learn something from it instead of trying to hide it pharmaceutically ... ?

There are many reports of beta-blockers used to reduce the body load with phenetylamines.

I have used them a few times as treatment for essential tremor. Actually, their primary effect is NOT on the blood vessels. They reduce the heart's workload. They improve the oxigen carrying capacity of blood, hence decreasing the heart rate, and as a consequence they decrease the blood pressure, which is influenced by the heart rate among other factors. But technically they are not vasoconstrictors, nor vasodilators.

The reason why they seem to work for certain anxiety processes is not clear, as far as I know. Before using them in the context of psychedelics ingestion, I would try them and observe the side effects involved. I'm not a fan of those, but you should find out by yourself.

In any case, agreed with endlessness here. Treat the source, not the symptom. This way you won't need beta-blockers, benzos or any other crutches.

^^ Alot of truth in this.The use of beta blockers in angina is to reduce the force of ventricular contraction and slowing down the heart rate which improves the filling of the coronary arteries during the ventricular relaxation phase (diastole).Its also thought that the effect on BP is due to central rather than peripheral effects.A very common side effect with beta blockers is cold peripheries which reflects an upset in vascular tone which requires both pre and post-synaptic alpha receptors and beta receptors.

The anxiety easing effects' mechanism is not fully clear but may represent some central action, plus, by reducing the somatic features of anxiety (eg sweaty palms, racing heart etc) it can break the process where panic can result from focussing on these physical features which can lead to a dreaded spiral of anxiety leading on occasion to a full-blown panic attack.

Once I took the beta blocker guanfacine with a certain nauseating shulgin phenylethylamine and had a great trip, sans body load.

Guanfacine is not actually a B blocker; its a centrally acting agonist at the alpha 2a receptor.