This subforum is dedicated to this very route of administration.
Yes, you can, but most people find digesting and purging solutions easier than actual plant material.
Look through some of the threads and see how others are doing it to get a general idea.
People for the most part generally use 3g of rue seeds, or 100-200mg of harmala extract depending on how pure it is. Some people report ingesting freebase can be a bit rough but others don't mind it, so you will have to experiment. You can also put your DMT dose in in some kind of juice that's high in Vit C and let that sit stirring occasionally in the fridge for a couple hours before hand to salt the freebase and possibly making it easier to digest. Maybe start with 50mg and work your way up to find your sweet spot. As you can see, you have some parameters to tweak.
oh and have a purge bucket, a glass of water, and a piece of fruit near by.
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