Planning my first kambo ceremony in a little more than a month, I started to prepair slowly the body and mind for this future challenge with caapi microdoses daily and weekly iboga microdose.

I hope that anyone having experience or planning to, interested in this special sapo frog venom application will chime in and share the knowledge, tips.
Any question are welcome. There is also two old thread about that I didn't resurrect from the internet memories, but you can find it easily by google kambo dmt-nexus or using the search engine.

Just as introduction for those who don't know about it yet. This is a copy from a articulate article of information.

"Kambo, Campu, Sapo, Vacino da Floresta, are all names for the waxy secretion of a frog living in the trees in the north-western part of the Amazon rainforest (on the border between Peru and Brazil, in Bolivia nd Colombia). The scientific name for this frog is Phyllomedusa bicolor or "Giant Monkey frog". Around 13 small tribes traditionally use this secretion to get rid of "Panema", or bad luck, to gain extra strength and stamina for their "hunting magic" sessions, and as a powerful medicine against malaria and other epidemic diseases. They claim the use of the secretion makes them strong, alert and invisible.
To harvest its secretion from the frog’s skin, the Indios stretch the animal by strings tied to its limbs. As painful as it may look, the frog is not harmed during this process, and is released in perfect health. According to the Indios, harming the frog could offend the animal spirit and result in severe misfortune. The medicine is crystallized on wooden sticks and can later be prepared for use by mixing the dried secretion with a few drops of water or saliva. The medicine is applied by burning tiny holes in the skin with the tip of a glowing stick. The effect is immediate and works in the body through the lymphatic system. Many shamans claim that they know how to use the frog’s secretion, but there have also been accounts of incorrect use which has led to death of the treated individual.

Scientific research on this frog started in the 1980’s. Italian scientist V. Erspamer of the University of Rome discovered that this frog is a "fantastic chemical cocktail with potential medical applications, unequalled by any other amphibian" (1). "Among the several dozen peptides found on Sapo, up to 7% are bioactive" (2), which means that they trigger chemical reactions in the human body. Researchers found 9 bioactive peptides with a potent effect on gastrointestinal muscles, gastric and pancreatic secretions, stimulation of the adrenalin cortex and the pituitary gland. "Phyllomedusin strongly affects intestines, bowels and contribute to violent purging. Phyllokinin causes dilatation of the blood vessels, which increases the permeability of the blood-brain barriers... Caerulein and sauvagine have an analgesic effect, enhance endurance, increase physical strength and more generally the capacity to face stress situations… Dermorphin and deltorphin are potent opioid peptides 4000 times stronger than morphine and 40 times stronger than b-endorphine" (3). Other interesting medicinal effects of Sapo, besides its anti-inflammatory properties, are "the capacity to destroy microbes" (4), heal infections, and regulate blood pressure. Sapo peptides properties cover a wide range of potential medical uses: treatment of brain diseases such as Alzheimer and Parkinson, depression, migraine, blood circulation problems, vascular insufficiency, organ diseases, cancer, fertility problems in women, AIDS, hepatitis and more. "The effects of the Sapo are heightened sensory perception, increased stamina, enhanced resistance to hunger and thirst" (5), a state of alertness, good mood etc. which can last for several days or weeks.

Studies on the Indio tribes using Sapo started in the 1930’s. After the 1950’s, western medicine started to develop interest in investigating this drug. In the eighties, during his visits to the Matses in Peru, P. Gorman documented his experience of the Sapo treatment he received. Samples of this frog were sent by him to western universities and before long pharmaceutical companies registered the first patents of Kambo peptides. Not surprisingly, the global pharmaceutical industry is now showing a keen interest in the medical properties of this frog’s slime. But although some of the peptides produced by this frog have been successfully reproduced in laboratories, this has not led to marketing a relevant medicine. Sapo started to be used outside of the Amazon rainforest and was no longer the exclusive realm of the Indios. Francisco Gomes, who has lived with the Katukina tribe for years, was a pioneer who made this medicine accessible to more people and in the cities of Acre. In 2003 the Katukina, guided by Chief Fernando, denounced the misuse of Kambo and accused the pharmaceutical companies who patented Kambo peptides of biopiracy. They claimed the rights of this medicine to the Katukinas and to other Amazonian tribes. In 2004 an alliance between the Katukina and the Brazilian government aimed to ensure that profits generated from the development of the kambo’s secretion will stay in the country and benefit the Katukinas. Since then, the Brazilian government has banned the use of Kambo in Brazil and any publicity of his properties. Recently a new association called M.A.T.S.E.S. has been created in Peru by dr. Dan Pantome in order to support the Indians who live in the Amazon. The aim of this association is to protect them from any kind of western speculations and give them a chance to survive. The whole area where the Matses live has recently been sold to an oil company. The cultural changes with which the indigenous Amazon tribes are faced at this moment develop at such a fast pace that western researchers do not have time to study the traditional way of living. The aim of this article is to remind us that an international law to protect these indigenous people and their traditions is needed urgently. The ancient knowledge of the Indians is precious heritage of mankind and we should do everything in our power to protect it from harm. "


References

1) P. Gorman, ‘Making magic’ from Omni, July 1993
2) P. Gorman, ‘Making magic’ from Omni, July 1993
3) P. Gorman, ‘Making magic’ from Omni, July 1993
4) P. Gorman, ‘Making magic’ from Omni, July 1993
5) ‘Ruolo dei peptidi antimicrobici nell’immmunita’ innata’, Universita’ La Sapienza di Roma, anno 2009-2010

Articles and essays

S. A. Romanoff, Matses adaptation in the peruvian Amazon, Ph.D. dissertation, Columbia University, New York, 1984.
V. Erspamer, G. F. & Cei, J. M. (1986) Comp. Biochem. Physiol. C 85, 125-137.
V. Erspamer, ‘Sostanze bioattive: dalla pelle di un anfibio al cervello zumano’, Accademia delle Scienze, Universita’ di Roma, La sapienza, 1987
'Frog secretion and hunting magic in upper Amazon: identification of a peptide that interact with adenosine receptor', J.W.Daly, J.Caceres, R.W.Moni, F/Gusovsky, M.Moos, K.B Simon, K.Milton and C.W.Myres, 1992

http://www.ayahuasca.com...he-spirit-of-the-shaman/
some links also.

Hi rOm. I have been with kambo maybe 25 to 30 times and had all kind of exepriences.
From absolutely to much and very mild.

Its always nice to have a sitter with you because if you go deep there is absolutely nothing else you can do than just surrender
and stay on the floor. Its good to have somebody giving you a clean bucket for your bile

Best adivse is to drink 1,5/ 2 liters of water just before applying the kambo.

It's very strong - you only need to make a small burn, enough to burn the outer layer of skin, then peel the outer layer off, mix a small amount of saliva with the poison (on the stick) and apply directly - this was how I was shown to apply it. I have an unnecessary scar/tattoo of patterned cigarette-sized burns from the kambo, but making a burn of this size turned out to be completely unnecessary. A small burn is plenty sufficient.

It's said to be good medicine for "opening up the heart", "burning away 'blockages' in one's life", or "mal aire" ('bad air' in the local terminology.

Dagger, I have a friend who did it around ten times and the scars are disapearing slowly but surely. So don't be afraid about that and the burn just need to be very superficial.

I don't know about altogether...cf rOm...the burns just need to be very superficial, and a point-sized burn (as if burned with the tip of an incense stick) should suffice.

As far as I know and from what I've read, although I've never participated in a Kambo ceremony, every paper i've read indicates that the burn can be almost entirely superficial, it doesn't need to be deep or pressed in, simply enough to remove the outer layer of skin.

Yes - and after the superficial burn you can rub the outer layer of skin, then apply the kambo.