A friend of mine came by from out of town for a couple of days and we enjoyed our company as men do.

We then proceeded to load up the Machine with DMT, my friend, being the cautious man he is, decided to linger at the 30-39mg dosages and after some (in his own words); rather dull experiences without any 'significant' changes in effect from 30 to 39 he took my advice and advanced.

In my experience the 30-39mg range is intense but comfortable so, it's without any challenge and being an adventerous man I quickly left the 30's to hang with the 40's and much to my pleasure came to realize how different the experiences were each time, it was almost like a new substance everytime.

My friend however continued to slowly go up in dose with +3-4 mg's tops and much to his dissapointment he ended up at 49mg without ANY significant change in effects, more than the "intensity" he said.

About this time I had decided to push the envelope even further and took my so-far highest dose at 52mg's and the experience was so real, that by the time it kicked in, I didn't know why "this" was happening, I had no recollection of taking any substance because everything was just TOO real.

Without going into further detail about my experience my friend was of course intrugied by my newly discovered grounds and wanted to have the full-range DMT experience already.

Now I don't push nor persuade anyone to do things they wouldn't do on their own but we had a discussion about the enormous subjectivity around DMT and came to common ground on the fact that he couldn't compare his dosage-range to mine. In doing so he had only been let down by dissapointment of his overly cautious approach because of reports commonly reporting very strong experiences at 40-50mg and the next time we meet he said he wanted to start off at 60mg's.

On 50mg my friend could talk normally and function quite good too, no more than CEV's.
On 50mg I'm mostly completely out of body with profound OEV's/CEV's that's usually not seperable.

We are always approaching the substance with great care and respect, we administer the substance in the exactly same fashion and help eachother in doing so. We use the same lighter, same batch/quality of spice, same method of administration etc.

The reason and sole purpose of this post is to show how humongously different DMT affects the people using it and how enormously the dosages may vary from person to person.

When in doubt, double the dose -Tim Leary

I don't doubt some variability in dosage requirements exists between individuals, but I reckon that doses in the 40s mg area if taken in one breath with correct vaporisation would be a heavy jaw-dropping type experience.The Machine does , from my chats with people who've used it extensively, suggests to me that there is definitely a degree of variability in how well the vaporisation goes and hence affects the experience.

It seems that people tend to become more sensitive to DMT over long-term exposure. It's most likely a matter of neuroplasticity.

A word of caution: the vast majority of disaster traumatizing stories from DMT that you'll find here on the Nexus have one gigantic greatest common factor, and that's large doses. Because of its extreme unpredictability, what 50mg does today, might do significantly less the next day and then take an unexpected turnaround for an experience double that of the original the day after. The first time (or one isolated time at all) with DMT should in no means be a gauge for what an appropriate dose should be. Vaping 60mg effectively on one's second time (or second set of experiences once at least a several day break has elapsed) can have some serious consequences. There's nothing to say that 50mg wouldn't floor him the next time he does it. The whole idea of starting low and slowly working your way up (starting at 30mg isn't really that low anyway, and going from 30-50mg in a few days isn't slow either) is so that you can familiarize yourself with what that dose range is; not to simply blow past it when it's ineffective. This isn't to say that your strategy couldn't work, and it seems to be serving you just fine, but realize that any expectation you set up for DMT is waiting to be knocked down. What either of you think a certain dose will do, can certainly do more or certainly do less. Some children will try to run before they can walk, and may do just fine. Perhaps these are the kids who will get to the olympics for track and field one day, but many will simply fall on their faces and might break some bones while they're at it.

Now, we have both used the substance for quite some time and in far lower dosages than 30mg but regardless of the experience's "fashion" these dosages were simply insufficient to achieve the desired effect. The desired effects was and still is real hallucinations, whereas "lower" dosages (for me less than 40mg~) doesn't possess the capability of producing such experiences.

Also, regarding

I believe this is largely because they recognize these experiences as too challenging and therefore "bad trips", instead of realizing that these are in my opinion some of the most important experiences one can have.



I believe this is true, although we do mimic each administration as good as possible to minimize the variables, this leaves us (in our theory) with the dosage and, perhaps, miniscule differences in methodology such as vaporization, lung capacity and whatnot.

There are a host of additional, immeasureable and unknown variables that may or may not include plasticity (which takes spiritual growth into account), effects of the individual's electromagnetic fields as produced by the body on the brain, metabolism, the individual's separate set and perhaps different reaction to setting, etc...Even when precisely measured doses were intravenously administered in Strassman's studies where vaporization issues and lung capacity and absorption don't even come into play, there are still worlds of difference from experience to experience while keeping the dose constant as demonstrated in his tolerance studies. Perhaps the rate by which DMT can polarize the action of the serotonin receptors and to what degree it achieves this polarization also plays a very large role.

Assuming that vaping technique has been tied down–

I think that an individual’s response to DMT can be highly variable and this isn’t always down to dose. The main factor I have come up against has been psychological, in some headstates it has been completely ineffective even when doubling my normal dose. For instance recently I tried at a very high stress time when my head was very, very busy and, perhaps stupidly, decided to see quite what I needed to get off the ground, I ended up giving up at 52mg (for me a very heavy dose is 35mg up). As Global points out there may well be physiological issues at play as well.

DMT dosage for vaporizing is very strange.. I read varying accounts online of people smoking anywhere upwards of 20-50mg of dmt for one hit.

With the spice I make the usual dose is only 20mg and you are shot into space. I cant even imagine more than that becuase that is the point where I usually lose touch with the world, forget who I am, and enter a chaotic dreamlike state of thoughts and visuals. I follow an A/B +defat procedure followed by freeze precip and purification of the evap to give clear white spice with a very fine appearance.

I have a 10^-3g scale to measure. I use glass oil burner to toke, first melting slowly then torching and very slowly inhaling.

Anyone else have similar experience?

EDIT: Tested my scale and it was grossly inaccurate, have update weight to a guestimated value until new scale arrives.

Kash,I can agree that different extracts have a big difference on strengths of the effect. At least for myself. Using STB, I have had less pure- slightly yellow extracts that get me no where, and then some white stuff that seemed to send me very far with much less.
I have not been able to get to the point where I only create the later.

I will also attest to the difference being a lot according to the person as the O.P. states. I can smoke, what feels like way too much, have to take 3 super large lung hurting tokes from my GVG and it rarely sends me very far. I actually have to use some kind of inhibitor to get anywhere it feels like. My girl friend needs not very much for her to go great places. For me, its very hard to get into hyperspace at all. And yes, I'm holding my hits in right.

I think people have very different tolerances for spice?

People should keep in mind that:
1) Scales truly accurate to 1 mg are rare and expensive--and usually even require special techniques to use, such as having an air guard: a gentle breath from a distance in the direction of a true milligram scale will itself register as a couple of milligrams.
2) True dosage is in mgs./kg., so absolute amounts don't translate as the same dose for different people--unless the people happen to be the same size.
3) Most variation in effects that people experience (with equally purified and equally measured material) are due to vaporization inconsistency. Lots of people have lots of trouble truly vaporizing AND fully inhaling AND sufficiently retaining an entire dose.

Ya makes me think there are a large number of alkaloid impurities that have white appearance and crystallize along with the dmt when following STB procedures, although it appears pure.

I definitly also agree that smoking technique is atleast half of the effectiveness of the spice.

EDIT: And your right swimfriend my scale was fuked up thankyou for getting me to check!

indeed. I think next time, swim will try A/B or STB with a good vinegar boil first at least. perhaps that will help purity and consistency.

Swim has found that he can get pure white stuff that varies a lot, sometimes seems very powerful, other times seems very week using STB and a few cleans.
It does seem odd to him.

and indeed - smoking technique, even with a gvg and a chore-boy seems to be a very touchy technique to get down. Swim has been at it over a year off and on and still considers himself a NoOb when it comes to getting a good hit. Swim still has much to learn on this whole affair to get it right.