I've always pondered if it may be beneficial for a person to consume Beta & Alpha blockers the day of tripping DMT/LSD or any overwhelming substance to help level the experience, keep it from getting out of hand. Of course this will take away immensely from the experience, but maybe something to explore. Personally SWIM has been in many overwhelming head spaces.

For those who don't know what Alpha & Beta blockers are, they block adreneline and other related chemicals from working with in the body.

Much love my fellow Terrestrials.

Seems kind of counterproductive to me.

If one wants to make the experience less overwhelming, one should stay away from the substances, simple.

It's to get a different look at the experience. Do we not mix chemicals to get a new perspective on the experience. This is the reason. Looking for information on the subject please. Thank you for your input, both of you. Much love fellow Terrestrials.

I have to agree with the other posters and say it's not worth it.
You're not going to get "a different look" at the experience because the experience won't be there in its entirety.

Sure, but there are things that you can count on with confidence, such as harmalas. Some man made drug just to block your adrenaline sounds something not worth doing.

I've tried it once with a low dose of mescaline (80mg) and low dose propanolol (10mg). Nothing really to report about at that dose, but i going to up those amounts possibly during future experimentation.

It definitely would alter the experience in a palpable way, but that's the whole point. Of course its not the same experience as what it is without. The reason i am interested in it, is i seem to get uncomfortable hypertension some times on certain psychedelics. For the sake of novelty, i wanted to try a beta blocker to see if it would help alleviate some of the negative body load, without affecting the experience as a whole too much. Everyone's body chemistry is different, and it could be beneficial for some, but not all.

I remain skeptical that it could be a panacea for body load/hypertension while tripping, or that it is a safe combo. But theres evidence to suggest that its been done before to no ill affects.

Just be very cautious, you are taking a pharmaceutical drug in combination with a psychedelic, and theres always the possibility that damage/harm is masked by whatever you introduce to counteract the negative elements. Use it at low doses and not often if at all at first, just in case something is up.

Check out a google search for beta blockers and mdma lsd on drugs forum. Some interesting info there about difference between alpha/beta and affects they have combined with mdma and lsd.

I'm going to come in from a different angle and say that propranolol does not add or take away from the psychedelic experience. It merely cancels out the peripheral effects of anxiety (tremor, sweating, flushing, racing heart, etc.). There is no psychoactive effect.

Inderal has improved my quality of life tremendously as I suffer from essential tremor and acute anxiety. There are no side-effects to report. It is the one pharm that does what it claims to do.

No need to take more than 20mg though.

I would agree on this, many high class musicians ( concert pianists amongst others) use them to control " stage fright" , without compromising their performance.

There are indeed side effects, you are just lucky you don't get them, and there are also lots of other pharms that do what they claim to do!

Peace

then it seems like you don't know what actually contributes to the psychedelic experience
hint: it's not the adrenergic receptors (think glutaminergic)

Although this is a different situation I was prescribed propranolol (twice daily dose I think, I forget the quantity but I believe it was quite high) for migraine a decade or so ago. I found they made me feel like I had my head in the clouds. When I realised this I took myself off them and threw them away.

this


propranolol is just an antagonist to adrenergic receptors, which are involved with visceral secondary responses from psychedelic ligands.

if im understanding this corrrectly the alpha/beta blockers wouldnt take away from the trip, just the edgy side effects, correct? would they help at all in the situation of a bad trip or would that be a whole different pharm?

I believe that's where gaba mediated drugs come in to play. Bad trips are more psychological and are treated with benzo's and antipsychotics. How i see it is, if theres bad vasoconstriction or other body issues (hypertension, tachardia) alpha and beta blockers would be the best bet. If you are having a freakout benzo's or antipsychotics.

But be extremely wary of combining drugs, taking a benzo to take the edge off of a trip is similar to tweekers drinking to calm their tweek. Don't get into a habit of it, and know its a speedball and most likely bad for your body/health. Alpha/beta blockers, when used correctly seem to be safe and beneficial to those who are in the circumstance of needing it. But never assume there could not be a negative/bad interaction between what you are taking and only do so in low doses when necessary.

Trips are usually a projection of your inner self. If you are finding it overwhelming, you may be suppressing inner emotions which are coming to surface when you trip.
their a 3 things you can do to work around this problem.
A) not take the substance
B) Use the trip to explore your thoughts, acknowledge them and let them go. If you have truly released all inner problems, you will never feel overwhelmed.
C) Take an Shamanistic approach. Ease your mind, do some meditation and when your mind is still then drop. I personally do this before all trips, makes the experience allot more meaningful. Hope this helps

I do feel lucky that there are no side effects for me, just relief!

Thank you all for the great information. SWIM has taken 20mg oxycodone before LSD and reports the ability to control the experience better, not having as much anxiety. Epiphanies are just as frequent, but the thought process is more stream line with less confusion. SWIM loves the confusion, but also enjoined the new look at an already epic experience. This is why SWIM was interested in the Beta/Alpha combinations. Much love fellow Terrestrials.