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Dmt tolerance Options
 
Elf Machine
#1 Posted : 11/9/2010 6:10:38 AM

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I know you should wait at least 30-60 mins between hits but can someone develope a tolerance with daily use?
 

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justine
#2 Posted : 11/9/2010 6:34:32 AM

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I think the consensus is that there is no tolerance build up with dmt, as long as you are able to vape efficiently you do
not have to wait at all. It's however not clear to me if there can be cross tolerance with other tryptamines.
To see the world in a grain of sand, and to see heaven in a wild flower, hold infinity in the palm of your hands, and eternity in an hour.
- William Blake
 
KwisatzHaderach
#3 Posted : 11/9/2010 6:38:49 AM

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Hey there,

The simple answer is no.

From Erowid's DMT Vault (http://www.erowid.org/chemicals/dmt/dmt_journal2.shtml):

Quote:

Tolerance to LSD, mescaline and psilocybin develops rapidly in man and animals, for some if not all behavioral effects.

In our initial efforts, we found that tolerance did not develop to unconditioned behavioral and EEG effects of DMT in cats administered DMT twice daily for 15 days or every 2 hours for 24 hours (34). Also, lack of behavioral tolerance has been reported in squirrel monkeys given DMT once daily for 38 days (35).

More recently, we studied the issue of tolerance in normal male volunteers who received 0.7 mg/kg of DMT intramuscularly twice daily for 5 days. Repeated administration did not consistently alter the peak blood concentration of DMT; autonomic changes in pupil size, pulse, or heart rate; the number of psychological items changed in a psychological scale; or the frequency of errors in a test requiring the subject to cross out a specific number in a list of random numbers. Three of the 4 subjects reported diminished subjective "highs" on a scale of 0 to 10 after two to four injections of DMT, but their subjective responses were variable from trial to trial and did not indicate a general loss of responsiveness to DMT. Rather, these subjects exhibited a variable or aperiodic partial tolerance to DMT. This pattern is reminiscent of Koella and associates' report of a cyclic change in ambulation produced by LSD in goats (36). Further studies, including longer or more frequent trials with DMT, are neccesary to fully evaluate this phenomenon.


If you are being denied from hyperspace, it is typically something within ourselves holding us back. Usually I take this as a sign to take a bit of a break.

Good luck!
Nothing lasts...nothing lasts...everything is changing into something else...nothing is wrong...nothing is wrong...everything is on the right track

In an interstellar burst
I'm back to save the Universe

 
Swarupa
#4 Posted : 11/9/2010 11:19:21 AM
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KwisatzHaderach wrote:


Quote:

In our initial efforts, we found that tolerance did not develop to unconditioned behavioral and EEG effects of DMT in cats administered DMT twice daily for 15 days or every 2 hours for 24 hours (34)




Cats? CATS?

What kinda sadistic f**k ran this study?

 
gammagore
#5 Posted : 11/9/2010 11:32:19 AM

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From personal experience I havent found any tolerance build up over a few days. Even the 30-60min thing falls out the window when some harmalas are added in.

Hyperspace will show you when you have had enoughSmile
 
embracethevoid
#6 Posted : 11/9/2010 12:39:20 PM

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Tolerance takes a very long period of time to build up. Prolonged high dose high duration oral use will result in semi-permanent tolerance. Once you explore a certain region of the cave, your brain thinks it no longer needs to go there again. However the cave is endless and 30 minute ventures into the depths of the cave are every bit as darkly lit as the first time.

However the tolerance spoken of here isn't exactly tolerance but acclimatisation.

gammagore wrote:
Hyperspace will show you when you have had enoughSmile


This.
 
MelCat
#7 Posted : 11/9/2010 12:49:43 PM

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Chronic wrote:
KwisatzHaderach wrote:


Quote:

In our initial efforts, we found that tolerance did not develop to unconditioned behavioral and EEG effects of DMT in cats administered DMT twice daily for 15 days or every 2 hours for 24 hours (34)




Cats? CATS?

What kinda sadistic f**k ran this study?




Convert a melodic element into a rhythmic element...
 
moyshekapoyre
#8 Posted : 10/12/2011 7:05:12 PM
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Namaste Nexians,

Has anyone else found that they have developed a tolerance to DMT and changa? I was smoking both daily for months, and never noticed tolerance... but then at some point it did seem to build up, maybe a month ago or more. Now, I can smoke a whole bowl full of powerful changa and just feel a bit meditative, and maybe some crappy CEVs.

I've also tried low-dose iboga, which used to be quite the euphoriant, but now it's not giving any joy.

I do recall OD'ing some DMT leaf that I smoked a while back (it was less than 80mg). Not sure if that might have been the cause... but I know that it took about 40 minutes to stop hallucinating with OEVs even after I got back to my body. I seem to recall having developed this kind of severe tolerance to mushrooms before developing it to changa, so it couldn't all be related to that DMT OD.

I guess the only way to turn my brain back to normal is to abstain from all substances for a good long while?
 
moyshekapoyre
#9 Posted : 10/12/2011 7:08:19 PM
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I may as well mention that I very rarely, if ever, broke thru on my DMT and changa smoking sessions... but not sure if that is relavent.

Also, I was thinking perhaps this has something to do with trying 5meomipt and DiPT at one point a few months ago.

I'm pretty sure that I have no special tolerance to ORAL dmt +harmalas, though, which is kind of odd, no? But yet oral iboga tolerance does exist.
 
tele
#10 Posted : 10/12/2011 10:28:43 PM
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There's actually no tolerance on DMT.
What could be happening is that you are/was overusing it and it won't allow you "in".
Has happened to me and some other members on the forum.

Waiting 2-5 weeks before next session should be enough. And very important as far as I can advice.
Smoking it daily for a month or more seems like overuse.
Smoking more than 3 times a week seems excessive and also not good for ones lungs, especially if you're combusting it, like with changa.
 
Simon Jester
#11 Posted : 10/12/2011 10:31:52 PM

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Forgive me if I may come off as a bit of an ass, I'm only trying to share my experience. I do not mean to chastise.

It seems that the problem has to do with the fact that you are taking small, sub-breakthrough doses on a very frequent basis. I've noticed that those who use DMT in this way will often develop a "tolerance" to the substance for a bit or, in unfortunate instances, get a big fat Hyperslap to teach them a lesson.

I don't believe that there are "right" and "wrong" ways of using any substance, but it seems to me that our brains will often prefer certain methods. It appears, by your descriptions of your DMT/Changa and Iboga use, that you are using these substances not as entheogens or to explore yourself and your world... But rather as euphoriants; to "get high". It is not uncommon, in instances such as the one I described, for the substance to "lose the magic" or even stop working altogether. This is even true when a person smokes marijuana constantly and gets stupid stoned 24/7. After a point they simply won't enjoy it as much, and it won't give the desired effects. When we exploit our passions, so to speak, we cheapen the qualities that made the activity so special.

Psychedelics are not just for inducing euphoria and feeling/seeing cool stuff though, they are seriously powerful drugs that drastically alter the functions of our brain. You're not just tickling a receptor like with opium or cannabis, you're turning on large neural networks and altering chemistry in such a way that the experience can have permanent, even very harmful effects on how our brain functions and how we think. Most psychedelic drug users desire this effect for spiritual/personal exploration, to strengthen their connection to their surroundings, etc etc... not simply to enjoy the effects. There are drugs better suited to simple euphoria, like cannabis or a little alcohol.

The solution to your problem, whatever the case, is fairly obvious: Take a good break from your drug use. Maintain a sober, comfortable state of mind for as long as it takes for you to evaluate your use and its effects on you, think about your physical health and happiness and allow your brain time to get back to "normal". This can be as short as a week or two, or as long as a lifetime... when and if you do decide to use drugs again, remember:

If you don't consider it special every single time you do it, it's not special at all.
 
moyshekapoyre
#12 Posted : 10/12/2011 10:51:49 PM
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@Simon:

I always tried to break through on DMT but the dose was never quite right, or something... one time I seemed to break through but it was just visual, not much else.

I tried to break through on changa but it was not heavy enough with harmalas. Then when I finally got it heavy enough, I realized I was too scared to leave my body.

But I have always used these things to help heal myself. Not as a 'get high party drug.' I don't smoke weed, don't drink alcohol, and I don't like that you recommended those things.

I tried to flood the iboga, but nearly died due to lack of a sitter. Since then I decided to microdose it. That worked very well for a while, but then my iboga ran out. If the iboga had not run out, i think i would be fine now. But since it did, I tried using tryptamines more regularly (I need a lot of healing), which was a bad idea, apparently.

Please take your assumptions elsewhere.
 
endlessness
#13 Posted : 10/13/2011 5:46:56 AM

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Ginkgo
#14 Posted : 10/13/2011 2:40:31 PM

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You could try microdosing Caapi for a few weeks, I've found that to help with dimishing tolerance and also helps with a lot of other things. The most important thing is to take a break. I'm not too sure I would smoke DMT every day for months. Then it becomes a routine, something normal, instead of an powerful otherwordly experience.
 
obliguhl
#15 Posted : 10/13/2011 6:05:03 PM

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Why does one need to smoke DMT and changa daily for months?
 
Caravel
#16 Posted : 10/17/2011 9:56:08 AM

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i have noticed a tolerance with dmt in the past

smoking 1-2 heavy doses daily (35-45mg)

after about 2 days the CEV had lost their sharp edges and visuals were more blured it seemed

after about about a week it was becomming dificult to get colors the crap visuals seemed black and white

after a couple weeks i remember a struggle for any visuals

ran out of spice

about a month later a friend braqng me over a hit of his recient x-tals did not weigh it but i remember assuming it was around 25mg hit it and i was blown away from here to saturn and back in 3 minutes full dragons on the wall and alien beings singing - i no longer smoke large quantities havent for over a year maby 5-6 doses in the past year but i get good sharp bright visuals each time

sorry if i dug up a dead post but i felt that i sould post my 2 cents worth

"Oh Dinah. It’s just a rabbit with a waistcoat... and a watch?!"
 
ivnep1
#17 Posted : 10/18/2011 5:59:14 PM

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Does Dmt have a tolerance?
All post are fictional.
 
ivnep1
#18 Posted : 10/18/2011 6:12:53 PM

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Sad
All post are fictional.
 
endlessness
#19 Posted : 10/18/2011 6:13:01 PM

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Hello and welcome to the Nexus!

On the top right part of the screen you have the search function. If you put "dmt tolerance" on the 'headers' box, you get a bunch of threads talking about this, such as:

https://www.dmt-nexus.me...spx?g=posts&t=26136
https://www.dmt-nexus.me...spx?g=posts&t=16900

also be sure to check the FAQ, it has plenty of answers and links to relevant questions. In this case:

https://wiki.dmt-nexus.m..._experiences_anymore_.3F
 
ivnep1
#20 Posted : 10/18/2011 10:25:52 PM

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well thank you!
All post are fictional.
 
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