SWIM absolutely thought she was a genius when she came up with brewing (separately) Rue and MHRB in water with some vinegar for several hours, reducing, and finally evaporating in a baking dish in the oven. It worked really, really well. Too well, her first time, as she didn't think to weigh the extracts out before putting them into the gelcaps.
*Ahem*
She really enjoys drinking her aya, and has enough fumarates that she would never need to do it with MHRB (at least, forseeably) but the taste of Rue makes her retch now and so if she were ever going to work with rue instead of doing a Manske, this is how she would do it.
Edit: The Rue was always fairly easy to collect, but the MHRB extract was slightly sticky and very difficult to scrape off the glass, crystalized like a sheet of very strong... something... crystalized steel!
PK Dick is to LSD as HP Lovecraft is to Mushrooms