What are the advantages and disadvantages of separating the harmine and the harmaline?

Links on reading are fine if you so desire.

Thanks yall

Harmaline is a more potent chemical than harmine by weight.

As the content of the plants these substances are extracted from varies quite significantly, seperation makes for more accuarate dosing. 100mg harmaline will have similar effects to 200mg harmine.

Also I find find harmaline has a sedating and almost cloudy effect, whereas harmine seems to let my head wonder more constructively. It's been said by some that it's placebo caused by the fact harmaline is stronger and these clouding effects will happen with larger doses of harmine, however I've used up to 500mg harmine and this clouding I experience with harmaline still was not apparent.