Would it by possible to 'basify' it as in a DMT A/B extraction, using NaOH or something similar? I should add that most commercially available 4-AcO-DMT comes as the fumarate salt.

i wouldn't do that..

Discussion of synthesis is not allowed on this forum.

changing a free base to a salt is one thing, but substituting functional groups is completely different, it treads into synthesis territory.
what this dude is asking is if a simple base hydrolysis of the acetyl group will convert it to a hydroxy group.

this exceeds his and your scope of practical chemistry, and I'll have to call you guys n00bs.

because more than likely, the product will have an oxyanion rather than a hydroxyl, and will be inactive

ahhh...ok...

then addition of the fumarate to dilute ammonia (edit* sodium bicarb is weak, ammonia will work better), followed by extraction with an organic
should work

I wouldn't use naphtha;

Tell your friend to use DCM or chloroform, there's really no other safe way around it.

check this out

https://wiki.dmt-nexus.m...fumarate_to_freebase.pdf

is there a post about why we dont talk about synth here? i know not to do it and have an idea why not to here but id like to see the official word.

it always seems to tread into amphetamine synthesis on other forums after a while.

• No discussion is allowed about synthesis of illegal substances, since it requires highly dangerous and watched chemicals. Discussion of simple safe non-comercial synthesis not requiring watched chemicals are tolerated (example: the reduction of dmt n-oxide to dmt with zinc, or the supposed lsa-to-lsh conversion)

https://www.dmt-nexus.me.../default.aspx?g=attitude

dude, you have been a member here for more than a year and you still havent read the Attitude page? check the link that ۩ kindly provided!

What would be the advantage of doing that? Why would you convert a fairly stable substance to one that is pretty much unstable, especially if they have extremely similar effects? People often ask for the opposite.

I guess he wants to vap it.

Yes, I am a noob in chemistry, hence I asked this question. Sorry if its implications lead into forbidden territory. My knowledge of chemistry didn't allow me to foresee that. The rules state "Discussion of simple safe non-comercial synthesis not requiring watched chemicals are tolerated (example: the reduction of dmt n-oxide to dmt with zinc, or the supposed lsa-to-lsh conversion)", and I didn't know what chemicals this would require. Feel free to change the title and subject to whatever is within the rules, and I'll try inquiring on a synthesis forum. Although, as benzyme suggested, converting 4-AcO-DMT to 4-HO-DMT is beyond the scope of what a guy can do in his bath tub with chemicals from the hardware store, right?

To clarify, I used the word 'basify' wrong; I was referring to the procedure described in the tek, and I asked whether that would be useful for converting 4-AcO-DMT to 4-HO-DMT. Sorry for the confusion.

sorry about the noob-calling, i was just kidding

but to answer your question, there's no easy way to chemically substitute the 4-AcO with 4-HO without rendering it inactive. the latter is very susceptible to oxidation

but your liver does it for you

So why not make freebase 4-Aco and vape it? It is more likely to work than psilocin, which may be subjected to thermal decomposition, like it happens when trying to vape freebase nicotine. Even for vaping (even though SWIM has never tried with either 4-AcO nor psilocin) 4-AcO would be the first best choice. It even crosses the blood brain barrier better.

you can most likely do it without DCM; make a 1:1 sodium carbonate paste with the 4-Aco fumarate and little water, thenlet it dry completely. this freebases the 4-Aco. The, you can pull with acetone or IPA or ethanol or methanol to get the freebases out.

I'd take the pH to 11.5 to 12.