So I've had a bit of experience with pharmahuasca. I use a syrian rue extract, by the way, with freebase DMT. My first dose was 100 mg. I kind of messed up the dosing a bit and took the DMT too late, but it was fun and it made moving around and playing with physics amazing. I bumped it with 50 mg and some more rue and it prolonged the trip and made it more of the same. Very little in the way of visuals. Good trip overall, nothing profound or anything but fun and I made a couple of neat drawings. My friend was there trip sitting me, as I prefer to do with all new substances at least the first time.

2nd dose: 150 mg+.5g of 10X syrian rue extract. Tactile sensations become overwhelming. I spend most of the trip rolling around on my bed and floor. Not very visual. Playing my electric violin was awesome. Cat is sooooo soft. Became completely enamored with life and it's beautiful complexity. The very fact that I'm alive is a miracle of chance. And the world we humans have built together is remarkably complex too. That a bunch of monkeys worked together enough to make the infrastructure we live on is amazing. Complexity in complexity inside of complexity. Great trip, loved it.

3rd dose: HOLY CRAP. Decide to dose 160 mg with .5 syrian rue. I give my friend 150 mg with .6 rue. I want him to experience the same "HOLY CRAP !!!LIFE!!!" feeling I had my second trip. He ended up just barely feeling it. I blasted off into the cosmos. It started with tactile sensitivity. Everything felt awesome. Moving was great. I just laid on the bed twisting myself around and feeling. I kept doing this for about an hour, just sitting there feeling everything and it was amazing. I was just a melting pot of senses. Eventually I kind of grew tired of this, but I couldn't stop. It seemed like my arms and legs writhed and squirmed on their own. They were twisting and throwing stuff around, and anything that went near my mouth was gently chewed on. So I got my friend to hand me my mp3 player and listened to music while writhing. I did internal inventory, analyzing my thought process and self criticizing. I came to terms with myself. Then there was more rolling. And singing. Singing was amazing, I sang along to "deep in the ocean" by lemon demon. Felt awesome. I wanted to talk, but I was tripping to hard to conceive things to talk about, so I started speaking in glossolalia. This was extremely fun, and I began singing a pure glossolalic song off the top of my head. Then I went back to my music for a bit. Sometime during it I had to pee (walking was difficult) and made my way to the bathroom. I stared at the mirror for what seemed like ages, my reflection was awesome. Eventually I parted with my beautiful face and laid on the floor and contact juggled for a while (surprisingly well, given my state). I was feeling the most profound sense of self love. I loved myself, and there nothing I could do about it. When my narcissist bout was over I got off the floor and back on my bed with the intention of drawing. I ended up putting my headphones back on and exploring the inner depths for a while. Then I got an amazing idea: What if I smoked some spice? I consulted my friend on whether or not this was a good idea. He said he didn't know, but I should be careful. I decided to do it. I think I had MGMT's latest 2 albums on random around this point. So I take a very week hit. Visuals increase 3 fold and it feels intense, but I'm not satisfied. I take another, thicker hit. The wall turns into a blur and the line between the wall and the ceiling becomes the edge of the universe, bright and infinite. I muster up my courage, fill my makeshift machine with a thick vapor and inhale. I'm in hyperspace, everything is as usual, filled with impossible architecture of color and strange morphing impossible corkscrews. A little more brown than usual, but nothing notably out of the ordinary. I begin moving again, writhing my arms around. My body had become sticks. I think I opened my eyes and attempted to communicate with my friend, but I could barely move and my speech came out as a low wail with words dispersed through it. "WAAAAARRRARRAGH-I-ARRGHAAA-CA-AAAARHFA-N'T-AAAARRRG-SEEM-AAARGAAARAA-TO-AAAARGHA-FIND-AAAAAA-MY-AARRAAGAA-WORDS-AAARGHA-IN-AAA-HERE-AAAAARAA" I manage to convey that it was intense and I was pretty gone. I find my head phones and close my eyes again. This is easily the best and most intense part of the trip, so I'm putting it in it's own paragraph.

I BECAME THE UNIVERSE. I was my house, my world, the ocean, the fish in the sea, the whales, even a crab being eaten, and the thing eating the crab. I was a gazelle, I was a giraffe, I was a lion. I was grass and atoms and everything. I was a sun, a planet, a solar system. EVERYTHING. At once. And I was, at the same time, nothing. I know I'm not the first to experience this kind of thing, but it was my first time, and it was magnificent.

I came out of it and was exhausted and sad. I was, for a moment, everything, and now I was just one again. I came to terms with it soon enough, watched the wall morph and stuff for a while, then eventually got it in me to sit up (that was ridiculously hard) and sketched a picture. It was an amazing trip. I feel bad my friend didn't get to experience a strong pharmahuasca trip though. The trip, from feeling it to it being mostly subsided lasted about 5 hours. It was probably the best trip of my life overall, and I highly recommend good sized doses of pharmahuasca.

By the way, does anyone else get intense headaches after a pharmahuasca trip? I've gotten them all 3 times a few hours after the trip ended, and when I went to bed soon after the trip when I woke up. It's horrendous, but worth it. I'm curious if it's just me or what.

Sounds intense- thanks for sharing! Any idea how long the hyperspace excursion lasted after vaping?

I've only worked with Jurema/Ayahuasca teas, but I almost always get a mean headache toward the end too. I get the impression it's blood pressure-related because I also always get super light-headed after standing up too quick or smoking even small amounts of cannabis after drinking the tea. Like my blood pressure's lower than normal. I've been trying to drink more water during the experience to prevent headaches from dehydration too. If I don't make the effort I usually forget to drink or eat anything at all, which would likely give me a headache even without the tea.

Have you tried a more selective diet before the trip? Maybe you're having a mild reaction to the MAOI. OK, no flames please- I'm aware that some think that tyramine/food reactions are BS for RIMAs, but I know druiddream over at the Ayahuasca forums swears that some people DO have reactions. This is based on multiple users' posts over there. He's been around for a while, so I tend to have a good bit of confidence in the veracity of his anecdotes. Anyway, I've heard that one of the primary symptoms of an adverse MAOI reaction is a headache. Diet seems to have no impact on my headaches, but I've always been a pretty 'clean' eater: no meat in the diet and very few aged cheeses and such. I do partake in some yummy aged/unfiltered ales once in a while, but never for at least a few days before drinking the brew.

-JM

I'm not sure how long I was in hyperspace, but it felt like an unusually short time. I wasn't smoking a full dose though, just smoking whatever was left over from the 20 mg I gave my friend in hopes of getting his trip started and the residue left in the pipe from all my previous sessions. As for the diet, I know RIMAs are considered safe with other food but I go out of my way to avoid meats and dairy on the day I take it anyways. I do eat chocolate while tripping, but nothing too excessive (a couple of reeses cups) but chocolate is generally considered safe with even prescription MAOIs unless you go way overboard. Over the course of the trip I drank a bottle of water and ate a banana too, so I don't think it's dehydration or diet related. I did feel light headed and had to stand slowly though, now that you mention it. Luckily I had the sense to keep some aspirin nearby this time, made the headache afterword more bearable.

Soulfood reports getting headaches from certain foods as well; seems like a very individualized thing.

Thanks for sharing the report!