no.

the difficulties aren't finding INMT, the difficulties are isolating the product in active concentrations.

Allow me to restate for my own clarification: you mean they can find it, but they can't be sure if the tiny amount they find is the remnant of a psychologically relevant quantity? Is this a technological issue, or do people just think it isn't there?

Can't we just grind up peoples head and do a STB?

it's there, and the technology exists for detecting the small amounts that do exist in the body, it's just that evolution has put a safety feature to prevent you from overloading yourself with DMT.
Rogan must have been joking when he said that "every night, your brain pumps heavy doses of dimethyltryptamine when you sleep." that is incorrect on several levels.

modern analytical equipment can detect levels as low as pico gram and whatever the next 3 orders of magnitude below that is. Detecting dmt is not the problem. the problem is more that its metabolized so easily as benzyme pointed out.

But not too many recent studies have looked at dmt in humans with modern equipment and techniques (as far as I know please post if someone has refs).

I mean in strassman's studies they naturally had to measure blood levels but I am talking about endogenous studies. In the past there was lot of interest in psychosis and endogenous tryptamines and thus analytical studies were done but they were done at a time when the techniques weren't as good. I would like to see such studies repeated and looked into deeper with more modern techniques.

^^I dunno where your going with this but I would like to point out that people (especially wacky people) have this obsession with convincing themselves that the pineal gland is some kind of master key to the spirit world. These theories are usually baseless and naive. Take such theories with a grain of salt unless real evidence is thrown down.

indeed

biochemistry isn't some conspiracy theory. it typically observes consistent behavior in metabolism and signal transduction. comparing it to questionable political agendas is not only far-fetched, it's not even relevant on any analogy, like comparing apples to b-flat major

the pineal gland is interesting
it's not even shrouded by the BBB, which is particularly odd
but it's probably not a dmt factory

*edit* i've actually had someone tell me that it's a grand medical conspiracy to deny that the pineal gland can actually produce DMT, and that's why there is no published literature showing this alleged evidence.

If DMT is not synthesized in the pineal gland, where is it from? Synthesized side-by-side with serotonin in the gut? The only thing pointing out that DMT may be synthesized in the pineal gland is the fact that it have all the enzymes needed, correct? What other places have these enzymes?

read the previous page, the answers are there with a link to a paper

Ok..so beyond all this DMT in the pineal/no DMT in the pineal..what is there that can cause these types of experiences?? Does it even need to happen in the pineal?? Can pinoline do these type of things?

I KNOW for a fact that endogenous tryptamine like visionary experiences are real because I have had them many times in the middle of the night..I wake up into it happening..its nothing like dreaming..its more like ayahuasca..but not as pressing mentally..if I get up and switch on the lights it ends and wont just come back when i turn them off..but its def there, I am not imagining this.

And also..YA..question, why do you put those spaces inbetween EVERY single line of your post? its a waste of space and makes me skip over the whole thing.

I've had a dozen or more of these 'waking up into it' experiences. As I get up and walk around, it slowly subsides over 10-15 minutes.

pinoline is definitely suspect.
it's well known that in the absence of light, the third-eye dilates.
hypothetically speaking, pinoline may prevent endogenous tryptamines from rapidly oxidizing. *shrugs*
but levels which lead to full-blown open-eyed fractal visions are not typically there, subtle imagery is more common.

the expression of INMT in the lungs, muscle, heart, and adrenals all points to the stress-response theory. dr. strassman
mentioned this theory in his book, and this certainly seems plausible. with the right focus and breathwork, similar states may also be attained

that makes no sense.
the point of science is to present evidence, or else theories are negated by the null hypothesis.
making analogies which have no relevance whatsoever doesn't support your argument.

Ever heard of flashbacks? Some people get them after they have particularly strong experiences with hallucinogens. Their minds slip back to the state during the trip, kind of like smelling something familiar and having a memory pop up (I often smell things that aren't there because of memories, but that's another story )

Anyway, not that I'm saying this is a flashback or not, but it's clear the mind can do crazy things without exogenous substances. I've hallucinated while meditating, and I've woken up in the middle of the night only to have a dream continue, superimposed on my visual field. I've had this stuff happen both before and after I began my research with hallucinogens.

The point is, this stuff can totally happen, and science doesn't know too much about why, what endogenous substances cause it, where they are produced in the body, etc. And it doesn't matter too much anyway. What does matter is that it's cool, can be useful, and you should do your best to enjoy it!

Fractal I think it is possible that levels of endogenous tryptamines can increase drastically in individuals and cause flashbacks, hallucinations and other effects. So many people report weird experiences like this something must be responsible for it. Sometimes its probably a combination of things that we probably are not even thinking about.

I just think its more complicated then Strassman and others have made it out to be. Most things involving alterations in consciousness are.

Its a difficult thing to get funding to study though unless you can relate it to neurological conditions or consciousness studies and try to pretend like the psychedelic part isn't the focus.

For those interested in these kinds of spontaneous mystical experiences I suggest looking up temporal lobe epilepsy. I believe drugs like lsd also have effects on the temporal lobe. This area of the brain when it goes crazy like in a temporal lobe seizure can cause hallucinations, feelings of being one with everything, etc. This could explain a lot of peoples so called "religious" visions.

Did you really have to spit that out?Now we're screwed

What benzyme says is no joke. Learning to suppress scientific evidence of dmt being produced in the pineal is one of the basic lessons during the scientific indoctrination. Suppression of this information is the cornerstone AND aim of science.

You forget to mention the flying saucers, the secret global government of man in black suits relying on alien technology and the coming invasion of satanic man-hating lesbians from the south, trained in deadly martial arts and with butterfly's tatoo'd on their buts and foreheads, the government and all the science community knows about but try to hide to the public because it would lead to mass panic, luting and people no longer paying for the subway but just hopping over the tourniquets.

Science lesson 5.67, page 336 of the secret 'great science almanak volume 7' written by the freemasons based on ancient knowledge they stole from the priory of sion.

I think flashbacks are related to PTSD, it makes the most sense in my mind. Even a positive trip that was very strong can be a traumatic enough experience to precipitate PTSD.

bollox