this is direct copy/paste from another post, though it should answer you question.
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SWIM's gonna make a pictorial when he decides to brew again, but here is SWIM's brewing method.
It should have equal or greater potency than resin.~~~~~~~~~~~~~~~~~~~~~~~~~
SWIM's experience in brewing has taught him 1 bit of truth.
Mescaline is MUCH more soluble in WATER than cactus goo.
The secret is to NOT use a sock and squeeze the goo out, all that is needed is a gentle decanting through a metal sifter.
There will be a little bit of sediment that will settle, that can be filtered or just decanted off later.
SWIM is still working out the solublity, though it was all done with dried flesh, could be different with fresh (but the fresh could be dried anyway)
Boiling water or Near-boiling is the best, it will not destroy the alkaloids, but there is NO NEED to simmer. Just use a container and add boiling water from a pot/kettle
(Hot tap water can be used for a very slightly less gooey product, but the amount to drink will be much higher)
Anyway the dried cactus will gooify loke 15-20ml/g of dried cactus.
Once there is a clearly a layer water above the cactus goo then the brewing can be started.
2-3 pulls of 10-15ml per g of cactus should be plenty for 99% (SWIM guesses) of the alkaloids.
Simply add the "pull" of boiling water atop the cactus goo then stir well several times over 1-2 hours.
LET THE MIX SETTLE, so the layers are very clear then gentle pour off the top layer.
Repeat the above step 2-3 times total (3 is best)
With each pull there is a CLEAR difference in color,
1:Red/brown
2:Yellowy/red
3:greeny/yellow with a hint of red
4:greeny yellow (no red alkloids left)
This is a non-reduction method so it is best to do so that way.
The brew is really still almost as nasty as simmered brews but it will be clear and just a tiny bit gelatinous instead of opaque and snotty.
SWIM's experience with it gave a cleaner and MORE intense experience compared to simmered brews AND dried cactus plain.Also note that as dose increases, nausea increase much faster, split the brew in 2 or 3 consume 20-40 minutes apart, you'll be happy you did.
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As for dose: (For SWIM)
10g is just above threshold
20g is very active but non-visual (except when trying to go to sleep, CEVs come out then)
30g is strong and mildly visual and extremely stimulating, almost too much
40g with passionflower tea 2 times throughout the trip was moderately visual and since the passionflower neutralized the mass stimulation it was less intense than the 30g
SWIM's threshold for visuals and psychedelics is medium/high so he recommends no more than 25g for the first try, some get full visuals off of 15g. Q21Q21's Tek: A comprehensive guide to extracting DMTThe 2 teks use non-toxic lime and vinegar and Tek 1: d-Limonene or Xylene or Tek 2: Naptha to produce very quick high yields with the greatest of ease.I am almost never on this site anymore so I will likely not answer PMs