Absolutely, avoid consuming prozac anytime near a Syrian rue dose - serotonin syndrome is not worth the risk.
As AwesomeUsername suggests, you will do best to get hold of actual Syrian rue seeds, but if you are in a position to experiment with the roots of this plant there's more than one of us here who would be interested to hear about it. You would be "doing your bit" in eliminating a "noxious weed", after all
(but make sure you're not uprooting someone's prize specimens; also - being patient and waiting until you can get hold of fresh seeds could also prove to be rewarding.)
The thing about Prozac and psychoactives was that it was (anecdotally?) found to protect against MDMA comedowns when taken at the right time afterwards. Seeing as this role can be fulfilled equally well using 5-HTP there seems to be little reason to court danger (or disappointment) with fluorinated psychopharmaceuticals. [It's also worth mentioning, it's better to avoid combining harmala (Syrian rue) with MDMA as well - but I can't say I know of any data regarding the use of Syrian rue
after the MDMA effects have worn off, not that that was even the question.]
βThere is a way of manipulating matter and energy so as to produce what modern scientists call 'a field of force'. The field acts on the observer and puts him in a privileged position vis-à-vis the universe. From this position he has access to the realities which are ordinarily hidden from us by time and space, matter and energy. This is what we call the Great Work."
β Jacques Bergier, quoting Fulcanelli