Chat GPT can answer all your extraction question.

I found it more helpful than waiting for answers on this forum.

Chat GPT is a helpful resource. Here is a link the Open AI https://chat.openai.com/

The following is an example of conversation had with the AI.


What is the general boiling point of DMT Salt?

The boiling point of DMT (dimethyltryptamine) salt, such as DMT hydrochloride or DMT fumarate, would depend on the specific salt form and the conditions under which it is heated. The salt form of DMT is more stable and less volatile than the freebase form.

In general, the boiling points of most DMT salts are higher than the temperatures typically used for vaporization or smoking, which are well below their boiling points. DMT is often vaporized or smoked at lower temperatures than its boiling point to avoid thermal degradation.

It's important to note that discussing the vaporization or smoking of DMT or any psychoactive substances raises legal and health considerations. Always prioritize safety and legality when handling such substances.


Give me it in terms of temperature in degrees celsius.

The boiling point of DMT salts, such as DMT hydrochloride or DMT fumarate, can vary depending on the specific salt form and purity. In general, they typically have boiling points within the range of 160 to 175 degrees Celsius (320 to 347 degrees Fahrenheit). It's important to understand that these salts are not commonly boiled but are instead typically vaporized or smoked at lower temperatures, as mentioned earlier.


So less than the boiling point of water?

Yes, the boiling points of DMT salts, which range from approximately 160 to 175 degrees Celsius, are lower than the boiling point of water, which is 100 degrees Celsius (212 degrees Fahrenheit) at standard atmospheric pressure. This is why DMT salts are typically vaporized or smoked at temperatures lower than their boiling points to avoid thermal degradation and to produce the desired psychoactive effects.


So in theory one could steep dmt containing plant matter in water to extract the alkaloid salts, then boil of the water and be left with the salts?

In theory, it is possible to use water to extract DMT-containing plant matter and then evaporate the water to obtain the DMT salts. However, there are several considerations and potential challenges in this process:

Water Solubility: DMT, in its freebase form, is not very water-soluble. To make it more water-soluble, it needs to be converted into a salt form using an acid (e.g., DMT hydrochloride). The extraction process typically involves an acid-base reaction to form the salt.

Plant Material: The success of the extraction depends on the nature of the plant material you are using and the DMT content in it. Not all plants contain significant amounts of DMT, so the yield may be low.

Legal and Safety Concerns: Handling and extracting DMT or DMT-containing plant material may raise legal and safety concerns, as DMT is a controlled substance in many places.

Technical Skill: Proper extraction techniques and safety measures are required to handle these substances effectively.

Ethical and Ecological Considerations: Many DMT-containing plants are sourced from the wild, and ethical and ecological considerations should be taken into account.

The extraction of DMT and related substances should be approached with caution, in full compliance with the law, and with a strong focus on safety and responsible practices. It's essential to prioritize ethical and legal considerations when working with such substances.


On the first point, the DMT is naturally already in salt form within the plant material. So after the alkaoids are collected and the water evaporated off I should ve left with salts which could then be converted to freebase using alkaline substance such as sodium carbonate?

If the DMT is naturally present in a salt form within the plant material, then your approach makes more sense. You can potentially extract the DMT salts using water and then evaporate the water to obtain the salts. Afterward, you can convert the salts to the freebase form using an alkaline substance such as sodium carbonate.

However, this process still requires care, skill, and adherence to legal and safety guidelines. Additionally, the quality and yield of the extraction can vary depending on the specific plant material and the extraction process.

It's crucial to conduct such activities responsibly, legally, and safely. Consult relevant literature or experts in the field for specific guidance and consider ethical and ecological factors when sourcing plant materials.


And by first extracting it in water it would filter out all the undesirable non water soluble planet material?

Yes, the use of water as a solvent can be effective in separating water-soluble compounds, including DMT salts, from non-water-soluble plant material. This process can serve as a form of crude purification and separation of the desired alkaloids from other plant components.

It's essential to perform the extraction carefully to minimize the inclusion of undesirable compounds and to maximize the yield of the target alkaloids. This may involve filtration, multiple extraction steps, and other purification techniques to improve the purity of the extracted material.

Again, when working with plant extractions and alkaloids like DMT, it's important to prioritize safety, legality, and responsible practices. Consult the relevant literature or experts for specific guidance on your extraction process.


Which field of science would specialise in the knowledge needed to successfully extract alkaloids from plant material?

The knowledge and techniques needed to successfully extract alkaloids from plant material are typically associated with several fields of science and can include:

Pharmacognosy: This field focuses on the study of natural products from plants and other sources, including the extraction and analysis of bioactive compounds like alkaloids.

Organic Chemistry: Knowledge of organic chemistry is crucial for understanding the chemical properties of alkaloids and the various chemical processes involved in their extraction and purification.

Analytical Chemistry: Analytical chemists specialize in techniques for separating, identifying, and quantifying chemical compounds, which is essential for analyzing plant extracts.

Botany: Understanding the types of plants that contain alkaloids, their growth conditions, and the parts of the plant where alkaloids are concentrated is important.

Ethnobotany: This field explores the traditional uses of plants, including those containing alkaloids, and can provide insights into extraction techniques.

Toxicology and Pharmacology: These fields are relevant for understanding the effects of alkaloids and their potential toxicity.

Environmental Science: Ethical and ecological considerations related to plant sourcing and sustainability are important when working with plant material.

In practice, a multidisciplinary approach may be necessary to successfully extract and work with alkaloids from plant material. Research institutions and universities with expertise in these fields often have departments or programs that focus on natural product extraction and analysis.

Yes it can be helpful, but it also makes mistakes, and not so seldom. I've tried asking fairly simple questions and it gave me obviously wrong answers. I asked for example how to convert MDMA.HCl to MDMA.Tartrate, and it said I should simply dissolve the HCl salt in IPA and add tartaric acid while stirring, the tartaric salt will precipitate out and settle over a few hours. Even without much chemistry knowledge, I know that this is wrong. So... Be careful with chatgpt, you have to know your stuff to a certain extent and then it can actually be helpful.

Yes I agree. It seems to not have access to chemistry publications behind paid walls. Perhaps a specialised individual AI bot would be created for specific fields of expertise for example chemistry, physics, medicine or law ect. It has general knowledge only and is reluctant to divuldge information related to illegal activity, or sometimes you have to probe it abit for the right information.

I wonder what the Chat GPT 4 Plus is like. $20 a month.

Be very careful. Just as an experiment I once asked ChatGPT advice for dosing MHRB in ayahuasca. It told me 50g is a normal dose

Well, I guess that counts as attempting to start doing your homework, but I'm not convinced it counts as actually exercising your brain. Case in point, I don't think you'd have posted the following if you'd thought about it for even half a second:This really underlines the caveat about the accuracy of information that ChatGPT spews out. It really is a probability-based prediction of the most likely successive word and has NO UNDERSTANDING of what it's talking about.

"Quick, cheap, good - choose two..."

So why are you still here? I mean, ChatGPT doesn't have a day job or a life so it seems like it can accommodate you better (errors it states aside).

One love

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Chat GPT3.5

Q) Does dmt alkaloid precipitate and form sediment on the bottom after basifying an aqueous solution containing dmt salts?

A) Yes, DMT (dimethyltryptamine) is known to precipitate and form a sediment when its salt form is basified in an aqueous solution. This process is often used in the extraction of DMT from plant material or other sources. When the pH of the solution is increased (basified) by adding a base such as sodium hydroxide, the DMT salt becomes less soluble in water and tends to form a solid precipitate that can be separated from the solution. This precipitate can be collected and further processed to obtain pure DMT.

Q) Does the dmt precipitate stay suspended in the solution or forms a sediment in the bottom?

A) In the process of basifying an aqueous solution containing DMT salts, the DMT will typically form a solid precipitate, which settles at the bottom of the container. It doesn't stay suspended in the solution. This precipitate can then be collected by decanting the liquid or through filtration, depending on the specific extraction or purification procedure being used. The separated DMT precipitate can be further processed to obtain the desired product.


So my thought are, I never see in an extraction of DMT technique with the step of siphoning off the most of basified liquid and discarding it, before pulling with a nonpolar solvent. Or simply could siphon off the basified liquid and keep the DMT sediment and dry out in a glass dish.

EDIT: User _Trip_ says

So the question remains then, what does precipitate so easily during initial basification step in standard acid/base extraction?

You don't see it in any extraction teks because that's not how it works... And as has been mentioned before, chatgpt does not "understand" things. If you extract DMT, salt it, dissolve that isolated salt in water and basify the solution, then DMT freebase will crash out and settle at the bottom (but that too will take a week or so). But in a bark soup with countless other stuff it doesn't work. The DMT doesn't crash out, you have to extract it with NPS. One explanation for that, as I have understood it, is that behavior of a substance in a solution depends on other solutes as well, the same substance can behave very differently depending on the make up of the solution.

People have repeatedly demonstrated that chat-GPT doesn't even understand simple physics. Someone asked it some simple questions on different ways to stack cubes, and it gave answers no human ever would....because they where completely impossible. Things like:"if i would place one cube on top of another, could i then place another cube next to the one on top of the other one?". And it answered:"yes".

And it isn't just that it doesn't understand the simplest things.

It's also that if you ask it questions on chemistry, it will look in all texts on chemistry available to it, to only predict wich words in answers to such questions are most likely to follow other words. That includes all texts that are completely wrong. And people have posted teks that simply don't work, or teks that are dangerous for various reasons.

There was a character here, who has been banned from our site but who is still posting on other sites under the name tregar, and he repeatedly posted teks here that fall in both the categories "ineffective" and "dangerous".

Chat-GPT is also going through all his posts or posts of other bullshitters, simply because they are on the internet.

I sometimes get quite a lot of precipitate immediately upon basifying soup. It turns white first then dark. If that's what you're referring to, i suspect that the darkish stuff that sinks is mostly tannins.

Chat GPT3.5.

Q) In a tea made with tannin containing plant material, will the dissolved tannins precipitate upon basification of the solution?

A) When you basify a tea made with tannin-containing plant material (such as tea leaves), the tannins are more likely to form insoluble complexes or precipitates. This reaction occurs because tannins can interact with alkaline substances (bases) and lose their solubility. The specific result can vary depending on the type and concentration of tannins, the pH level to which you basify the solution, and other factors.

The precipitation of tannins upon basification is commonly used in some traditional methods of clarifying tea and wine. It helps remove tannins and other undesirable compounds, leading to a smoother and less astringent taste.


Yeah it makes sense. From what I read tannins have significantly higher molecular weight, 500 - 20 000 daltons, compared to alkaloids which have, 100 - 900 daltons. Tannins would therefore presumably precipitate first, while the alkaloids remain suspended in the solution at low concentration.

When I do a mini A/B starting with concentrated and relatively pure DMT, basifying causes white clouds that if left alone drift to the top of the water as an oil.

I would not trust chat GPT.

Also, maybe you should examine your impatience and desire for an immediate answer OP. I could be wrong, but it does not seem healthy.

Ah sweet thanks for the observation about concentrated mini A/B's and precipitation.

I agree with you and it cannot be said enough. Chat GPT has no comprehension at all, not in the human sense. Chat GPT is similar to Google but it can understand your questions and string together a bunch of words and point you on the right direction for further learning. The difference between Chat GPT and Google is the latter will fetch you wesites and articles which you have to read to find what your looking for, whereas the former reads the websites and articles and gives the most probable answer.


Chat GPT3.5.

Q) Explain yourself?

A) I'm ChatGPT, an AI language model created by OpenAI. I'm here to provide information, answer questions, and engage in conversations on a wide range of topics. I'm based on the GPT-3.5 architecture and have been trained on a diverse dataset up until January 2022. How can I assist you today?

Q) How should you be used?

A) I can be used in various ways, including:

Answering questions: You can ask me questions on a wide range of topics, and I'll do my best to provide informative responses.
Generating content: I can help you create written content, such as essays, articles, or even creative writing.
Learning and research: You can use me to explore new topics, learn about different subjects, and gather information for your studies or research. Coding and technical assistance: I can assist with coding questions, debugging, and programming-related inquiries.
Language translation: I can translate text from one language to another.
Conversational partner: You can engage in conversations with me on various topics, providing a virtual chat companion.

It's important to keep in mind that while I can provide information and generate text, my responses are generated based on the text data I've been trained on, and I may not always have the most up-to-date information. Always verify critical information from reliable sources. Additionally, please use me responsibly and ethically.

Is this incorrect? GPT4 is excellent, in my opinion, but I don't know shit about extractions or chemistry. The way you prompt the questions has a huge impact on the answers you get, though.

ChatGPT3.5

Q) Is there more molecules of calcium hydroxide per gram than bufotenine?

A) The number of molecules in a gram of a substance is determined by Avogadro's number, which is approximately 6.022 x 10^23 molecules per mole. To compare the number of molecules in a gram of calcium hydroxide (Ca(OH)2) and a gram of bufotenine (C12H16N2O), we need to consider their molar masses.

Calcium Hydroxide (Ca(OH)2):

Molar Mass = 40.08 g/mol (Ca) + 2(16.00 g/mol (O) + 1.01 g/mol (H)) = 74.10 g/molNumber of moles in 1 gram = 1 g / 74.10 g/mol ≈ 0.0135 molesNumber of molecules in 1 gram ≈ 0.0135 moles x 6.022 x 10^23 molecules/mole

Bufotenine (C12H16N2O):

Molar Mass = 12.01 g/mol (C) + 1.01 g/mol (H) + 14.01 g/mol (N) + 16.00 g/mol (O) = 43.03 g/mol
Number of moles in 1 gram = 1 g / 43.03 g/mol ≈ 0.0232 moles
Number of molecules in 1 gram ≈ 0.0232 moles x 6.022 x 10^23 molecules/mole
Now, you can compare the two calculated numbers to determine which substance has more molecules per gram. Keep in mind that these calculations are approximations and consider the molar masses and Avogadro's number. The actual number of molecules in a gram of each substance may vary slightly due to isotopic composition.

Q) So which one has more molecules per gram of weight?

A) Based on the calculations I provided earlier, bufotenine (C12H16N2O) has more molecules per gram of weight compared to calcium hydroxide (Ca(OH)2).

In 1 gram of bufotenine, there are approximately 0.0232 moles, which corresponds to a larger number of molecules (approximately 0.0232 moles x 6.022 x 10^23 molecules/mole). In contrast, 1 gram of calcium hydroxide contains approximately 0.0135 moles, resulting in a smaller number of molecules.

So, bufotenine has a greater number of molecules per gram than calcium hydroxide.

Q) In terms of a ratio of one to another?

A) To compare the ratio of molecules per gram of bufotenine (C12H16N2O) to calcium hydroxide (Ca(OH)2), you can simply divide the number of molecules per gram of bufotenine by the number of molecules per gram of calcium hydroxide.

Number of molecules per gram of bufotenine / Number of molecules per gram of calcium hydroxide

Using the values from the previous calculations:

(0.0232 moles x 6.022 x 10^23 molecules/mole) / (0.0135 moles x 6.022 x 10^23 molecules/mole)

This simplifies to:

(0.0232 / 0.0135)

The ratio is approximately 1.72.

So, bufotenine has approximately 1.72 times more molecules per gram compared to calcium hydroxide.

Q) Thank you. Dick head.

A) You're welcome. If you have any more questions in the future, feel free to ask. I'm here to help.

ChatGPT 3.5 really messed up the bufotenine MW calculation there
That's the calculation for cyanic acid, HOCN.

Thanks for underlining the warning against relying on this system for critical technical matters.

Wikipedia, molar mass.
Calcium hydroxide CA(HO)2: 74.093 g/mol. 1g/74.093g/mol = 0.0134965516 moles
Bufotenine C12H16N2O: 204.273 g/mol. 1g/204.273g/mol = 0.0048954096 moles


ChatGPT 3.5

Q) Calcium hydroxide CA(HO)2: 74.093 g/mol. 1g/74.093g/mol = 0.0134965516 moles Bufotenine C12H16N2O: 204.273 g/mol. 1g/204.273g/mol = 0.0048954096 moles. So which one has more molecules?

A) I apologize for the earlier incorrect calculations. Thank you for providing the correct molar masses and calculations.

With the corrected values:

1 gram of calcium hydroxide (Ca(OH)2) contains approximately 0.0135 moles, which corresponds to approximately 0.0135 moles x 6.022 x 10^23 molecules/mole = 8.13 x 10^21 molecules.

1 gram of bufotenine (C12H16N2O) contains approximately 0.0049 moles, which corresponds to approximately 0.0049 moles x 6.022 x 10^23 molecules/mole = 2.96 x 10^21 molecules.

Therefore, calcium hydroxide has more molecules per gram compared to bufotenine, as it contains approximately 8.13 x 10^21 molecules per gram, while bufotenine contains approximately 2.96 x 10^21 molecules per gram.

Q) As a ratio of one to the other?

A) To compare the ratio of molecules per gram of calcium hydroxide (Ca(OH)2) to bufotenine (C12H16N2O):

Number of molecules per gram of calcium hydroxide / Number of molecules per gram of bufotenine

Using the corrected calculations:

(8.13 x 10^21 molecules per gram of calcium hydroxide) / (2.96 x 10^21 molecules per gram of bufotenine)

This simplifies to:

(8.13 / 2.96)

The ratio is approximately 2.75.

So, calcium hydroxide has approximately 2.75 times more molecules per gram compared to bufotenine.

So sometimes have to feed it the right information, and check it's results.

That's the thing. You ALWAYS have to double check every single word it says, or you'll end up believing wrong information more often than not.

Even with really simple tasks, like multiplying two numbers, it likes to get it wrong. Example:





Or how about another example:



This one was pretty surprising. It actually got all the intermediate results right - that's a first in my experimentation. However, when adding them up, it got it wrong again.



In the case of calculation, aside from the fact that python always gets it right and gpt rarely does, python also does it quicker, for free, with no network requests, and using almost no power.

Obviously that's not a fair comparison, since the idea behind gpt really isn't to do calculations like that.

Even with your example of bufo calculations though, you woulda had the correct result much quicker if you simply looked up the correct values and formula yourself. My guess is that if you hadn't posted it here, and dfz didn't point out that it's wrong, you woulda just relied on gpt's answer.

And that's how we'll go down as a species, if we keep believing that there's an I in AI.

Btw, that's what i mean when i say i'm not willing to train their thing for free, or even pay for it. OpenAI can pay me if they want me to educate their brainless child.